Development Level

Tbio 397 | 10,625
Tdark 161 | 7,003
Tchem 54 | 1,890
Tclin 10 | 602

Collection

Eligible Kinase Proteins 9 | 134
Eligible Ion Channel Proteins 7 | 117
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 32 | 633
preweaning lethality, incomple... 15 | 260
embryonic lethality prior to t... 14 | 187
decreased bone mineral content 11 | 157
embryonic lethality prior to o... 11 | 148
abnormal behavior 9 | 226
abnormal bone structure 8 | 131
decreased total body fat amoun... 8 | 186
decreased lean body mass 7 | 195
increased bone mineral content 7 | 92
increased lean body mass 7 | 107
decreased body weight 6 | 174
decreased bone mineral density 6 | 126
increased fasted circulating g... 6 | 68
small testis 6 | 37
abnormal embryo size 5 | 112
decreased grip strength 5 | 123
hyperactivity 5 | 108
increased circulating alkaline... 5 | 119
short tibia 5 | 82
abnormal gait 4 | 51
abnormal testis morphology 4 | 30
decreased circulating serum al... 4 | 79
decreased circulating triglyce... 4 | 83
decreased eosinophil cell numb... 4 | 41
decreased prepulse inhibition 4 | 52
increased circulating calcium ... 4 | 32
increased grip strength 4 | 83
abnormal coat/ hair morphology 3 | 18
abnormal retina morphology 3 | 100
abnormal sleep behavior 3 | 63
cardiovascular system phenotyp... 3 | 35
decreased circulating insulin ... 3 | 75
decreased threshold for audito... 3 | 32
increased blood urea nitrogen ... 3 | 44
increased circulating HDL chol... 3 | 63
increased circulating chloride... 3 | 43
increased circulating triglyce... 3 | 24
increased exploration in new e... 3 | 56
increased mean corpuscular hem... 3 | 93
increased or absent threshold ... 3 | 128
increased startle reflex 3 | 38
prenatal lethality prior to he... 3 | 64
abnormal behavioral response t... 2 | 52
abnormal bone mineralization 2 | 55
abnormal heart left ventricle ... 2 | 20
abnormal lens morphology 2 | 73
abnormal placenta size 2 | 10
abnormal retinal vasculature m... 2 | 15
abnormal tail movements 2 | 12
decreased body length 2 | 108
decreased circulating LDL chol... 2 | 37
decreased circulating bilirubi... 2 | 14
decreased circulating creatini... 2 | 31
decreased circulating magnesiu... 2 | 11
decreased hemoglobin content 2 | 53
decreased lactate dehydrogenas... 2 | 14
decreased leukocyte cell numbe... 2 | 54
decreased lumbar vertebrae num... 2 | 62
decreased mean corpuscular hem... 2 | 34
decreased vertical activity 2 | 22
enlarged heart 2 | 111
hypoactivity 2 | 89
increased circulating LDL chol... 2 | 15
increased circulating glycerol... 2 | 11
increased circulating phosphat... 2 | 24
increased circulating potassiu... 2 | 31
increased erythrocyte cell num... 2 | 26
increased heart weight 2 | 37
increased hemoglobin content 2 | 45
increased mean corpuscular vol... 2 | 91
increased prepulse inhibition 2 | 21
increased rib number 2 | 41
increased sacral vertebrae num... 2 | 62
increased total body fat amoun... 2 | 57
male infertility 2 | 62
pale yolk sac 2 | 12
pallor 2 | 13
vertebral transformation 2 | 12
abnormal body wall morphology 1 | 7
abnormal coat appearance 1 | 25
abnormal cranium morphology 1 | 32
abnormal heart morphology 1 | 51
abnormal locomotor activation 1 | 26
abnormal neural tube closure 1 | 37
abnormal retinal inner nuclear... 1 | 5
convulsive seizures 1 | 11
decreased NK cell number 1 | 16
decreased caudal vertebrae num... 1 | 49
decreased heart weight 1 | 44
decreased mean corpuscular vol... 1 | 50
enlarged spleen 1 | 26
female infertility 1 | 34
increased body length 1 | 20
increased circulating choleste... 1 | 53
persistence of hyaloid vascula... 1 | 22
small thymus 1 | 11
thin ventricular wall 1 | 5
thrombocytopenia 1 | 46
tremors 1 | 34

Disease

ovarian cancer 341 | 8,484
medulloblastoma, large-cell 325 | 6,234
osteosarcoma 318 | 7,933
glioblastoma 292 | 5,572
atypical teratoid / rhabdoid tumor 240 | 4,369
psoriasis 207 | 6,685
oligodendroglioma 196 | 2,849
pilocytic astrocytoma 184 | 3,086
primitive neuroectodermal tumor 184 | 3,031
lung cancer 172 | 4,466
ependymoma 161 | 2,514
intraductal papillary-mucinous neoplasm (IPMN) 157 | 3,289
pediatric high grade glioma 155 | 2,712
astrocytic glioma 141 | 2,241
Breast cancer 140 | 3,094
intraductal papillary-mucinous adenoma (IPMA) 140 | 2,956
Pick disease 139 | 1,893
intraductal papillary-mucinous carcinoma (IPMC) 128 | 2,988
lung carcinoma 118 | 2,844
subependymal giant cell astrocytoma 118 | 2,287
malignant mesothelioma 117 | 3,162
Carcinoma 113 | 2,147
invasive ductal carcinoma 109 | 2,950
non-small cell lung cancer 104 | 2,798
adult high grade glioma 101 | 2,148
medulloblastoma 99 | 1,524
interstitial cystitis 94 | 2,299
lung adenocarcinoma 94 | 2,713
group 3 medulloblastoma 93 | 2,254
pituitary cancer 89 | 1,972
group 4 medulloblastoma 84 | 1,875
astrocytoma 81 | 1,493
pancreatic cancer 79 | 2,300
ulcerative colitis 73 | 2,087
sonic hedgehog group medulloblastoma 71 | 1,482
ductal carcinoma in situ 66 | 1,745
juvenile dermatomyositis 66 | 1,189
posterior fossa group A ependymoma 64 | 1,511
Cancer 62 | 2,346
breast carcinoma 61 | 1,614
pancreatic ductal adenocarcinoma liver metastasis 61 | 1,795
adrenocortical carcinoma 60 | 1,427
cystic fibrosis 60 | 1,665
atypical teratoid/rhabdoid tumor 57 | 1,095
Multiple myeloma 56 | 1,327
posterior fossa group B ependymoma 56 | 1,530
tuberculosis 51 | 1,557
acute quadriplegic myopathy 50 | 1,157
progressive supranuclear palsy 49 | 674
primary pancreatic ductal adenocarcinoma 48 | 1,271
colon cancer 43 | 1,475
spina bifida 43 | 1,064
Rheumatoid Arthritis 41 | 1,160
active Crohn's disease 39 | 918
diabetes mellitus 39 | 1,663
cutaneous lupus erythematosus 38 | 1,056
dermatomyositis 34 | 933
nasopharyngeal carcinoma 33 | 1,056
Alzheimer's disease 32 | 644
Atopic dermatitis 31 | 944
aldosterone-producing adenoma 31 | 664
Intellectual disability 27 | 573
acute myeloid leukemia 26 | 780
gastric cancer 26 | 430
hepatocellular carcinoma 26 | 532
chronic rhinosinusitis 25 | 512
primary Sjogren syndrome 25 | 789
Down syndrome 24 | 548
non primary Sjogren syndrome sicca 24 | 840
gastric carcinoma 23 | 832
pancreatic carcinoma 23 | 567
Obesity 22 | 616
Duchenne muscular dystrophy 21 | 602
Neurodegenerative disease 21 | 383
Parkinson's disease 21 | 364
Schizophrenia 21 | 501
Waldenstrons macroglobulinemia 21 | 765
autosomal dominant Emery-Dreifuss muscular dystrophy 21 | 499
esophageal adenocarcinoma 21 | 737
Acquired metabolic disease 19 | 267
hereditary spastic paraplegia 19 | 313
tuberculosis and treatment for 6 months 19 | 686
Epilepsy 18 | 346
fibroadenoma 18 | 557
Amyotrophic Lateral Sclerosis 17 | 431
Autistic Disorder 17 | 320
Multiple Sclerosis 17 | 498
interstitial lung disease 16 | 291
nephrosclerosis 15 | 329
Bipolar Disorder 14 | 266
glioblastoma multiforme 14 | 347
urothelial carcinoma 14 | 318
Endometriosis 13 | 535
mucosa-associated lymphoid tissue lymphoma 13 | 480
non-inflammatory breast cancer 13 | 208
non-small cell lung carcinoma 13 | 413
Prostatic Neoplasms 12 | 471
active ulcerative colitis 12 | 477
Crohn's disease 11 | 304
Vascular disease 11 | 281

Tissue

Nervous System 615 | 18,561
Digestive Tract 614 | 18,473
Endocrine System 614 | 18,512
Female tissues 614 | 18,647
Liver and Pancreas 614 | 18,136
Urinary Tract 614 | 18,444
Cardiovascular System 613 | 17,958
Male tissues 612 | 17,969
Skin and soft tissues 611 | 18,115
Respiratory system 610 | 17,484
Blood and immune system 609 | 17,995

Target Family

Non-IDG 345 | 11,971
Enzyme 149 | 4,146
Transcription Factor 36 | 1,400
Kinase 27 | 634
Transporter 20 | 473
Epigenetic 16 | 242
Ion Channel 16 | 341
GPCR 9 | 406
TF/Epigenetic 3 | 38
Nuclear Receptor 1 | 48

Jensen-KB Tissue

Amygdala 622 | 622
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Small nuclear ribonucleoprotein F SNRPF Tdark Non-IDG -0.25254 1.81 65
V-type proton ATPase catalytic subunit A ATP6V1A Tbio Enzyme -1.80191 64.7 120
Trifunctional enzyme subunit alpha, mitochondrial HADHA Tbio Non-IDG -2.96515 948.2 132
Replication factor C subunit 5 RFC5 Tbio Non-IDG -1.02728 11.1 64
Myelin basic protein MBP Tbio Non-IDG -3.69577 5257.0 715
Beta-1,3-galactosyltransferase 2 B3GALT2 Tdark Enzyme 0.13 0.55 88
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A ANKRD28 Tbio Enzyme -0.56847 4.64 67
Ras-related protein Rab-14 RAB14 Tbio Enzyme -1.40555 28.2 91
Serine/threonine kinase-like domain-containing protein STKLD1 STKLD1 Tdark Kinase 0.00000 156
Polyhomeotic-like protein 3 PHC3 Tbio Non-IDG -2.68637 475.4 59