Development Level

Tbio 104 | 10,625
Tdark 42 | 7,003
Tchem 19 | 1,890
Tclin 11 | 602

Collection

Eligible Kinase Proteins 3 | 134

IMPC Term

preweaning lethality, complete... 10 | 633
abnormal behavior 4 | 226
decreased bone mineral density 4 | 126
decreased total body fat amoun... 4 | 186
enlarged heart 4 | 111
abnormal bone structure 3 | 131
decreased circulating creatini... 3 | 31
decreased threshold for audito... 3 | 32
hypoactivity 3 | 89
abnormal digit morphology 2 | 13
abnormal retina morphology 2 | 100
decreased blood urea nitrogen ... 2 | 31
decreased circulating lipase l... 2 | 2
decreased erythrocyte cell num... 2 | 43
decreased lean body mass 2 | 195
decreased startle reflex 2 | 48
embryonic lethality prior to o... 2 | 148
enlarged spleen 2 | 26
increased bone mineral density 2 | 52
increased circulating choleste... 2 | 53
increased grip strength 2 | 83
preweaning lethality, incomple... 2 | 260
abnormal cervical vertebrae mo... 1 | 4
abnormal coat/ hair morphology 1 | 18
abnormal embryo size 1 | 112
abnormal heart morphology 1 | 51
abnormal response to new envir... 1 | 8
abnormal rib morphology 1 | 28
abnormal seminal vesicle morph... 1 | 47
abnormal stomach morphology 1 | 4
abnormal thoracic vertebrae mo... 1 | 16
abnormal tooth morphology 1 | 24
absent ovary 1 | 2
decreased KLRG1+ CD4 alpha bet... 1 | 2
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased cardiac muscle contr... 1 | 5
decreased caudal vertebrae num... 1 | 49
decreased circulating amylase ... 1 | 24
decreased circulating choleste... 1 | 85
decreased circulating glucose ... 1 | 121
decreased circulating insulin ... 1 | 75
decreased circulating iron lev... 1 | 25
decreased circulating serum al... 1 | 79
decreased effector memory CD8-... 1 | 24
decreased hemoglobin content 1 | 53
decreased rib number 1 | 59
decreased vertical activity 1 | 22
embryonic lethality prior to t... 1 | 187
hyperactivity 1 | 108
impaired pupillary reflex 1 | 14
improved glucose tolerance 1 | 56
increased bone mineral content 1 | 92
increased circulating alkaline... 1 | 119
increased circulating iron lev... 1 | 25
increased fasted circulating g... 1 | 68
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased respiratory quotient 1 | 12
increased total body fat amoun... 1 | 57
limb grasping 1 | 35
prenatal lethality prior to he... 1 | 64
prolonged PR interval 1 | 4
rib fusion 1 | 2
short tibia 1 | 82
small superior vagus ganglion 1 | 20
thrombocytopenia 1 | 46
vertebral fusion 1 | 23

Disease

ovarian cancer 122 | 8,484
osteosarcoma 80 | 7,933
medulloblastoma, large-cell 66 | 6,234
psoriasis 61 | 6,685
glioblastoma 60 | 5,572
lung cancer 54 | 4,466
atypical teratoid / rhabdoid tumor 51 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 41 | 3,289
invasive ductal carcinoma 38 | 2,950
intraductal papillary-mucinous carcinoma (IPMC) 33 | 2,988
malignant mesothelioma 33 | 3,162
oligodendroglioma 33 | 2,849
intraductal papillary-mucinous adenoma (IPMA) 32 | 2,956
Multiple myeloma 31 | 1,327
ependymoma 31 | 2,514
pilocytic astrocytoma 31 | 3,086
astrocytic glioma 30 | 2,241
pediatric high grade glioma 30 | 2,712
Breast cancer 29 | 3,094
adult high grade glioma 29 | 2,148
lung adenocarcinoma 28 | 2,713
non-small cell lung cancer 27 | 2,798
pancreatic cancer 27 | 2,300
lung carcinoma 25 | 2,844
ulcerative colitis 24 | 2,087
Pick disease 23 | 1,893
acute quadriplegic myopathy 23 | 1,157
pancreatic ductal adenocarcinoma liver metastasis 23 | 1,795
Cancer 22 | 2,346
pituitary cancer 22 | 1,972
juvenile dermatomyositis 21 | 1,189
subependymal giant cell astrocytoma 21 | 2,287
adrenocortical carcinoma 20 | 1,427
dermatomyositis 19 | 933
primitive neuroectodermal tumor 19 | 3,031
Rheumatoid Arthritis 18 | 1,160
interstitial cystitis 18 | 2,299
tuberculosis 18 | 1,557
astrocytoma 17 | 1,493
colon cancer 17 | 1,475
ductal carcinoma in situ 17 | 1,745
group 4 medulloblastoma 17 | 1,875
breast carcinoma 16 | 1,614
group 3 medulloblastoma 16 | 2,254
primary pancreatic ductal adenocarcinoma 16 | 1,271
Waldenstrons macroglobulinemia 15 | 765
diabetes mellitus 15 | 1,663
posterior fossa group B ependymoma 15 | 1,530
medulloblastoma 14 | 1,524
sonic hedgehog group medulloblastoma 13 | 1,482
atypical teratoid/rhabdoid tumor 12 | 1,095
tuberculosis and treatment for 6 months 12 | 686
Carcinoma 11 | 2,147
aldosterone-producing adenoma 11 | 664
spina bifida 11 | 1,064
Prostatic Neoplasms 10 | 471
cystic fibrosis 10 | 1,665
gastric carcinoma 10 | 832
non primary Sjogren syndrome sicca 10 | 840
posterior fossa group A ependymoma 10 | 1,511
Duchenne muscular dystrophy 9 | 602
Neurodegenerative disease 9 | 383
esophageal adenocarcinoma 9 | 737
Amyotrophic Lateral Sclerosis 8 | 431
Atopic dermatitis 8 | 944
Mammary Neoplasms 8 | 410
Parkinson's disease 8 | 364
hereditary spastic paraplegia 8 | 313
nasopharyngeal carcinoma 8 | 1,056
progressive supranuclear palsy 8 | 674
Alzheimer's disease 7 | 644
Congenital adrenal hyperplasia 7 | 74
Polycystic Ovary Syndrome 7 | 332
acute myeloid leukemia 7 | 780
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 499
Endometriosis 6 | 535
IGA Glomerulonephritis 6 | 454
Obesity 6 | 616
Stomach Neoplasms 6 | 282
cutaneous lupus erythematosus 6 | 1,056
glioblastoma multiforme 6 | 347
pancreatic carcinoma 6 | 567
Adenoma 5 | 165
Renal Cell Carcinoma 5 | 199
active Crohn's disease 5 | 918
chronic rhinosinusitis 5 | 512
mucosa-associated lymphoid tissue lymphoma 5 | 480
non-small cell lung carcinoma 5 | 413
primary Sjogren syndrome 5 | 789
Arthritis 4 | 248
Asthma 4 | 349
Atrial Fibrillation 4 | 110
Hyperandrogenism 4 | 32
Hypertension 4 | 287
Hypertensive disease 4 | 193
Intellectual disability 4 | 573
Paraplegia 4 | 71
Vascular disease 4 | 281
hepatocellular carcinoma 4 | 532
nephrosclerosis 4 | 329

Tissue

Cardiovascular System 175 | 17,958
Digestive Tract 175 | 18,473
Endocrine System 175 | 18,512
Female tissues 175 | 18,647
Nervous System 175 | 18,561
Blood and immune system 174 | 17,995
Liver and Pancreas 174 | 18,136
Male tissues 174 | 17,969
Urinary Tract 174 | 18,444
Skin and soft tissues 173 | 18,115
Respiratory system 172 | 17,484

Target Family

Non-IDG 96 | 11,971
Enzyme 53 | 4,146
Transcription Factor 9 | 1,400
Kinase 7 | 634
Transporter 6 | 473
Epigenetic 2 | 242
GPCR 2 | 406
Ion Channel 1 | 341

Jensen-KB Tissue

Adrenal gland 176 | 176
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
V-type proton ATPase catalytic subunit A ATP6V1A Tbio Enzyme -1.80191 64.7 120
Ras-related protein Rab-14 RAB14 Tbio Enzyme -1.40555 28.2 91
Heat shock 70 kDa protein 14 HSPA14 Tbio Non-IDG -1.54921 38.4 79
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.21113 124.2 150
PAX-interacting protein 1 PAXIP1 Tbio Non-IDG -1.59834 42.1 69
C-X-C chemokine receptor type 4 CXCR4 Tclin GPCR -3.38245 2485.7 991
Tropomodulin-3 TMOD3 Tbio Non-IDG -1.05720 12.8 81
N-terminal Xaa-Pro-Lys N-methyltransferase 1 NTMT1 Tbio Enzyme -0.98900 9.15 77
Stathmin-3 STMN3 Tbio Non-IDG -1.11235 13.0 133
Stress-associated endoplasmic reticulum protein 1 SERP1 Tbio Non-IDG -1.35469 29.5 75