Development Level

Tbio 117 | 11,651
Tdark 37 | 6,593
Tchem 12 | 1,388
Tclin 11 | 612

Collection

Kinase: IDG Consortium (Target... 4 | 125
RFA-RM-18-021 4 | 328

IMPC Phenotype

preweaning lethality, complete... 14 | 979
preweaning lethality, incomple... 5 | 499
abnormal behavior 4 | 298
decreased total body fat amoun... 4 | 207
decreased vertical activity 4 | 208
embryonic lethality prior to o... 4 | 239
enlarged heart 4 | 210
increased bone mineral density 4 | 72
abnormal embryo size 3 | 220
decreased body length 3 | 101
decreased circulating creatini... 3 | 39
embryonic lethality prior to t... 3 | 278
abnormal bone structure 2 | 187
abnormal eye morphology 2 | 68
decreased caudal vertebrae num... 2 | 53
decreased erythrocyte cell num... 2 | 62
decreased startle reflex 2 | 75
enlarged spleen 2 | 41
hypoactivity 2 | 132
increased bone mineral content 2 | 108
increased total body fat amoun... 2 | 134
abnormal bone mineralization 1 | 38
abnormal coat- hair morphology 1 | 19
abnormal hair growth 1 | 10
abnormal heart morphology 1 | 162
abnormal response to new envir... 1 | 10
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal stomach morphology 1 | 10
abnormal tooth morphology 1 | 24
absent ovary 1 | 3
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
embryonic growth retardation 1 | 106
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
limb grasping 1 | 41
male infertility 1 | 123
microphthalmia 1 | 26
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
short tibia 1 | 97
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56
unresponsive to tactile stimul... 1 | 8

Disease

ovarian cancer 122 | 8,520
Carcinoma 95 | 11,493
osteosarcoma 80 | 7,950
medulloblastoma, large-cell 66 | 6,241
glioblastoma 65 | 5,792
psoriasis 61 | 6,694
atypical teratoid / rhabdoid tumor 60 | 5,112
lung cancer 56 | 4,740
ependymoma 51 | 4,679
adult high grade glioma 46 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 41 | 3,291
invasive ductal carcinoma 38 | 2,951
Breast cancer 35 | 3,578
astrocytic glioma 35 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 33 | 2,989
malignant mesothelioma 33 | 3,232
oligodendroglioma 33 | 2,850
intraductal papillary-mucinous adenoma (IPMA) 32 | 2,955
Astrocytoma, Pilocytic 31 | 3,081
Multiple myeloma 31 | 1,332
lung adenocarcinoma 28 | 2,716
pancreatic cancer 28 | 2,398
Cancer 27 | 2,499
non-small cell lung cancer 27 | 2,890
lung carcinoma 25 | 2,843
group 3 medulloblastoma 24 | 4,104
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,962
Pick disease 23 | 1,894
acute quadriplegic myopathy 23 | 1,158
tuberculosis 23 | 2,010
group 4 medulloblastoma 22 | 1,855
pituitary cancer 22 | 1,972
ulcerative colitis 22 | 1,819
juvenile dermatomyositis 21 | 1,187
subependymal giant cell astrocytoma 21 | 2,287
Rheumatoid arthritis 20 | 1,191
adrenocortical carcinoma 19 | 1,428
dermatomyositis 19 | 966
primitive neuroectodermal tumor 19 | 3,035
Autosomal recessive predisposition 18 | 1,442
interstitial cystitis 18 | 2,312
breast carcinoma 17 | 1,638
colon cancer 17 | 1,478
ductal carcinoma in situ 17 | 1,745
diabetes mellitus 16 | 1,728
Waldenstrons macroglobulinemia 15 | 765
primary pancreatic ductal adenocarcinoma 15 | 1,109
Epilepsy 14 | 792
Kidney cancer 14 | 2,613
Seizures 14 | 596
Cognitive delay 13 | 608
Global developmental delay 13 | 608
Mental and motor retardation 13 | 608
pediatric high grade glioma 13 | 1,064
Prostatic Neoplasms 12 | 495
astrocytoma 12 | 1,146
Intellectual disability 11 | 1,016
Muscle hypotonia 11 | 571
aldosterone-producing adenoma 11 | 665
cystic fibrosis 11 | 1,696
spina bifida 11 | 1,074
non primary Sjogren syndrome sicca 10 | 891
Amyotrophic lateral sclerosis 9 | 451
Breast Neoplasms 9 | 445
Cerebellar Ataxia 9 | 304
Duchenne muscular dystrophy 9 | 601
Dull intelligence 9 | 645
Low intelligence 9 | 645
Mammary Neoplasms 9 | 425
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Neurodegenerative disease 9 | 414
Poor school performance 9 | 645
esophageal adenocarcinoma 9 | 737
gastric carcinoma 9 | 807
Alzheimer's disease 8 | 658
Atopic dermatitis 8 | 952
Liver Cirrhosis, Experimental 8 | 769
Parkinson's disease 8 | 392
hereditary spastic paraplegia 8 | 318
nasopharyngeal carcinoma 8 | 1,058
progressive supranuclear palsy 8 | 676
sonic hedgehog group medulloblastoma 8 | 467
tuberculosis and treatment for 6 months 8 | 409
Anemia 7 | 365
Congenital adrenal hyperplasia 7 | 73
Failure to gain weight 7 | 365
Nystagmus 7 | 317
Pediatric failure to thrive 7 | 365
Polycystic ovary syndrome 7 | 360
Renal Cell Carcinoma 7 | 214
Small head 7 | 374
Stomach Neoplasms 7 | 300
acute myeloid leukemia 7 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
Obesity 6 | 678
Optic Atrophy 6 | 242
Schizophrenia 6 | 1,160
Short stature 6 | 531
cutaneous lupus erythematosus 6 | 1,057

Tissue

Endocrine System 174 | 18,159
Digestive Tract 173 | 17,369
Female tissues 173 | 17,400
Male tissues 173 | 17,142
Nervous System 172 | 16,725
Skin and soft tissues 172 | 17,230
Liver and Pancreas 171 | 16,750
Respiratory system 171 | 16,393
Urinary Tract 171 | 16,678
Blood and immune system 170 | 16,909
Cardiovascular System 165 | 15,192

Target Family

Non-IDG 97 | 12,091
Enzyme 53 | 4,145
Transcription Factor 9 | 1,400
Kinase 7 | 634
Transporter 6 | 473
Epigenetic 2 | 242
GPCR 2 | 408
Ion Channel 1 | 344

Jensen-KB Tissue

Adrenal gland 177 | 177
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Probable ergosterol biosynthetic protein 28 ERG28 Tdark Non-IDG -1.25331 16.7 40
Poly(A)-specific ribonuclease PARN PARN Tbio Enzyme -1.87605 76.4 263
Activator of 90 kDa heat shock protein ATPase homolog 1 AHSA1 Tbio Enzyme -1.65208 50.3 564
F-box/LRR-repeat protein 5 FBXL5 Tbio Non-IDG -1.25684 20.6 145
Ubiquitin carboxyl-terminal hydrolase isozyme L5 UCHL5 Tbio Enzyme -1.71687 51.9 225
N-acetyltransferase 9 NAT9 Tdark Enzyme -3.02820 1070.9 44
Kinesin-like protein KIF22 KIF22 Tbio Non-IDG -1.69996 54.3 147
MIF4G domain-containing protein MIF4GD Tbio Non-IDG -1.20548 16.5 75
G-protein-signaling modulator 3 GPSM3 Tbio Non-IDG -1.97857 92.6 35
Equilibrative nucleoside transporter 1 SLC29A1 Tclin Transporter -2.61544 427.2 413