Development Level

Tbio 27 | 11,445
Tchem 5 | 1,598
Tdark 2 | 6,588
Tclin 1 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

increased startle reflex 5 | 112
abnormal bone structure 4 | 187
increased heart weight 4 | 62
increased circulating sodium l... 2 | 71
preweaning lethality, complete... 2 | 979
abnormal bone mineralization 1 | 38
abnormal digit morphology 1 | 10
abnormal eye size 1 | 7
abnormal lens morphology 1 | 81
abnormal response to tactile s... 1 | 17
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal vibrissa morphology 1 | 25
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating total pr... 1 | 49
decreased lean body mass 1 | 135
embryonic lethality prior to o... 1 | 239

Disease

Carcinoma 26 | 11,493
ovarian cancer 24 | 8,520
lung cancer 15 | 4,740
osteosarcoma 15 | 7,950
invasive ductal carcinoma 14 | 2,951
psoriasis 14 | 6,694
ductal carcinoma in situ 12 | 1,745
breast carcinoma 11 | 1,638
fibroadenoma 11 | 559
Cancer 10 | 2,499
glioblastoma 10 | 5,792
pancreatic cancer 10 | 2,398
Obesity 9 | 678
atypical teratoid / rhabdoid tumor 9 | 5,112
diabetes mellitus 9 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
medulloblastoma, large-cell 9 | 6,241
Autosomal recessive predisposition 8 | 1,442
colon cancer 8 | 1,478
lung adenocarcinoma 8 | 2,716
Breast cancer 7 | 3,578
Polycystic ovary syndrome 7 | 360
adult high grade glioma 7 | 3,801
lung carcinoma 7 | 2,843
pituitary cancer 7 | 1,972
tuberculosis 7 | 2,010
Kidney cancer 6 | 2,613
Kidney disease 6 | 430
Multiple myeloma 6 | 1,332
group 3 medulloblastoma 6 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
non-small cell lung cancer 6 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Acromegaly 5 | 51
Astrocytoma, Pilocytic 5 | 3,081
Hypertensive disease 5 | 292
Hypoparathyroidism 5 | 41
Liver Cirrhosis, Experimental 5 | 769
Liver cancer 5 | 604
Muscle hypotonia 5 | 571
Pick disease 5 | 1,894
Substance Withdrawal Syndrome 5 | 55
adrenocortical carcinoma 5 | 1,428
astrocytoma 5 | 1,146
ependymoma 5 | 4,679
interstitial cystitis 5 | 2,312
primary pancreatic ductal adenocarcinoma 5 | 1,109
substance-related disorder 5 | 162
Acrodysostosis 4 | 12
Adenoma 4 | 167
Adrenal gland cancer 4 | 12
Arthritis 4 | 290
Biliary tract cancer 4 | 19
Bone cancer 4 | 16
Brachydactyly 4 | 156
Carney complex 4 | 25
Cervix carcinoma 4 | 10
Cushing syndrome due to macronodular adrenal hyperplasia 4 | 5
Cushing's syndrome 4 | 48
DOID:3297 4 | 4
Dull intelligence 4 | 645
Fatty liver disease 4 | 103
Fibrodysplasia ossificans progressiva 4 | 17
Fibrous dysplasia 4 | 15
Hyperphosphatemia 4 | 32
Hypertension 4 | 396
Hyperthyroidism 4 | 53
Hypothyroidism 4 | 122
Intellectual disability 4 | 1,016
Low intelligence 4 | 645
McCune Albright syndrome 4 | 19
Mccune-Albright Syndrome 4 | 4
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Monostotic fibrous dysplasia 4 | 4
Multiple Endocrine Neoplasia Type 1 4 | 29
Nystagmus 4 | 317
Ossifying fibroma 4 | 15
Pituitary adenoma 4 | 38
Plummer's disease 4 | 11
Poor school performance 4 | 645
Primary pigmented nodular adrenocortical disease 4 | 13
Progressive disorder 4 | 142
Progressive osseous heteroplasia 4 | 4
Pseudohypoparathyroidism 4 | 18
Pseudohypoparathyroidism type 1C 4 | 4
Pseudohypoparathyroidism, Type 1B 4 | 5
Pseudopseudohypoparathyroidism 4 | 6
Schizophrenia 4 | 1,160
Seizures 4 | 596
Small intestine cancer 4 | 12
Stomach Neoplasms 4 | 300
Stomach cancer 4 | 30
Thyroid cancer 4 | 36
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
malignant mesothelioma 4 | 3,232
oligodendroglioma 4 | 2,850
pediatric high grade glioma 4 | 1,064
subependymal giant cell astrocytoma 4 | 2,287

Tissue

Blood and immune system 32 | 16,909
Cardiovascular System 32 | 15,192
Digestive Tract 32 | 17,369
Endocrine System 32 | 18,159
Female tissues 32 | 17,400
Liver and Pancreas 32 | 16,750
Respiratory system 32 | 16,393
Skin and soft tissues 32 | 17,230
Urinary Tract 32 | 16,678
Male tissues 31 | 17,142
Nervous System 31 | 16,725

Target Family

Non-IDG 19 | 12,091
Enzyme 14 | 4,145
GPCR 1 | 408
Transcription Factor 1 | 1,400

Jensen-KB Tissue

Adipocyte 35 | 35
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytochrome b-c1 complex subunit 1, mitochondrial UQCRC1 Tbio Enzyme -1.46124 30.0 217
Diacylglycerol O-acyltransferase 2 DGAT2 Tchem Enzyme -2.07482 112.0 230
Paired amphipathic helix protein Sin3b SIN3B Tbio Non-IDG -1.34131 21.4 148
Protein ALEX GNAS Tbio Non-IDG -2.63356 1389.7 509
Calcium-independent phospholipase A2-gamma PNPLA8 Tbio Enzyme -1.96549 89.5 114
Melanocortin-2 receptor accessory protein MRAP Tbio Non-IDG -3.60469 4145.9 102
Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas GNAS Tbio Non-IDG -2.63356 1389.7 509
Annexin A6 ANXA6 Tbio Non-IDG -2.44893 298.8 381
Citrate synthase, mitochondrial CS Tbio Enzyme -2.61735 325.4 239
Ras-related protein R-Ras RRAS Tbio Enzyme -2.15870 149.8 150