Development Level

Tbio 18 | 11,445
Tdark 3 | 6,588
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

vertebral fusion 23 | 23
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 15 | 11,493
medulloblastoma, large-cell 14 | 6,241
osteosarcoma 14 | 7,950
ovarian cancer 13 | 8,520
psoriasis 11 | 6,694
atypical teratoid / rhabdoid tumor 9 | 5,112
ependymoma 8 | 4,679
glioblastoma 8 | 5,792
malignant mesothelioma 8 | 3,232
primitive neuroectodermal tumor 7 | 3,035
adult high grade glioma 6 | 3,801
group 3 medulloblastoma 6 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Breast cancer 5 | 3,578
Kidney cancer 5 | 2,613
Pick disease 5 | 1,894
astrocytic glioma 5 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
oligodendroglioma 5 | 2,850
Astrocytoma, Pilocytic 4 | 3,081
Obesity 4 | 678
adrenocortical carcinoma 4 | 1,428
subependymal giant cell astrocytoma 4 | 2,287
Alzheimer's disease 3 | 658
Cancer 3 | 2,499
Intellectual disability 3 | 1,016
Rheumatoid arthritis 3 | 1,191
astrocytoma 3 | 1,146
colon cancer 3 | 1,478
invasive ductal carcinoma 3 | 2,951
juvenile dermatomyositis 3 | 1,187
lung adenocarcinoma 3 | 2,716
lung cancer 3 | 4,740
pancreatic cancer 3 | 2,398
pediatric high grade glioma 3 | 1,064
progressive supranuclear palsy 3 | 676
Abdominal Pain 2 | 98
Abnormal vision 2 | 52
Colorectal Neoplasms 2 | 243
Dull intelligence 2 | 645
Fatty liver disease 2 | 103
Glioma 2 | 74
Immune system cancer 2 | 140
Kidney disease 2 | 430
Low intelligence 2 | 645
Melanoma 2 | 711
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Neurodegenerative disease 2 | 414
Ophthalmoplegia 2 | 106
Photodysphoria 2 | 121
Photophobia 2 | 121
Poor school performance 2 | 645
Skin cancer 2 | 469
acute myeloid leukemia 2 | 783
breast carcinoma 2 | 1,638
diabetes mellitus 2 | 1,728
gastric cancer 2 | 459
gastric carcinoma 2 | 807
group 4 medulloblastoma 2 | 1,855
interstitial cystitis 2 | 2,312
lung carcinoma 2 | 2,843
medulloblastoma 2 | 720
non-small cell lung cancer 2 | 2,890
spina bifida 2 | 1,074
tuberculosis 2 | 2,010
tuberculosis and treatment for 6 months 2 | 409
Abnormal color vision 1 | 31
Abnormal respiratory patterns 1 | 20
Acne 1 | 52
Amyloidosis 1 | 67
Biliary cirrhosis 1 | 45
Cerebral cortex myoclonus 1 | 3
Color vision defect 1 | 33
Color vision defect, severe 1 | 31
Cone/cone-rod dystrophy 1 | 20
HYPOCALCEMIA, AUTOSOMAL DOMINANT 1 1 | 2
HYPOCALCEMIA, AUTOSOMAL DOMINANT 2 1 | 1
HYPOCALCIURIC HYPERCALCEMIA, FAMILIAL, TYPE II (disorder) 1 | 1
Hanot's cirrhosis 1 | 8
Hemiparesis 1 | 34
Hyperkyphosis 1 | 111
Hypermagnesiuria 1 | 3
Hypocalciuric hypercalcemia, familial, type II 1 | 1
Increased calcium level in kidney 1 | 21
Kyphosis deformity of spine 1 | 114
Malignant melanoma of choroid 1 | 3
Malignant melanoma of ciliary body 1 | 3
Malignant melanoma of iris 1 | 4
Myasthenias 1 | 8
Neoplasms, Experimental 1 | 40
Obsessive compulsive behavior 1 | 25
Phakomatosis cesioflammea 1 | 2
Phakomatosis cesiomarmorata 1 | 1
Reduced visual acuity 1 | 63
SERUM PHOSPHATE ELEVATED 1 | 14
Wiskott-Aldrich syndrome 1 | 30
cone-rod dystrophy 1 | 59

Tissue

Endocrine System 23 | 18,159
Skin and soft tissues 23 | 17,230
Female tissues 22 | 17,400
Male tissues 22 | 17,142
Nervous System 22 | 16,725
Respiratory system 22 | 16,393
Urinary Tract 22 | 16,678
Blood and immune system 21 | 16,909
Digestive Tract 21 | 17,369
Liver and Pancreas 21 | 16,750
Cardiovascular System 20 | 15,192

Target Family

Non-IDG 11 | 12,091
Enzyme 5 | 4,145
Epigenetic 3 | 242
Transcription Factor 3 | 1,400
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
X-box-binding protein 1 XBP1 Tchem Transcription Factor -2.90444 780.2 514
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184
Centromere protein J CENPJ Tbio Non-IDG -1.79588 59.0 102
Decaprenyl-diphosphate synthase subunit 2 PDSS2 Tbio Enzyme -1.35453 23.3 163
Selenoprotein N SELENON Tbio Non-IDG -1.95384 87.6 96
Protein phosphatase 1 regulatory subunit 42 PPP1R42 Tdark Enzyme -0.42597 2.49 79
Chromobox protein homolog 5 CBX5 Tbio Epigenetic -1.90801 83.4 624
Tetratricopeptide repeat protein 28 TTC28 Tdark Non-IDG -0.50526 3.76 3
Lysophospholipase-like protein 1 LYPLAL1 Tbio Enzyme -1.18623 14.4 127
Homeobox protein GBX-1 GBX1 Tbio Transcription Factor -1.18074 14.9 100