Development Level

Tbio 28 | 11,651
Tchem 4 | 1,388
Tclin 4 | 612
Tdark 3 | 6,593

IMPC Phenotype

tremors 39 | 39
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 31 | 11,493
ovarian cancer 25 | 8,520
osteosarcoma 23 | 7,950
medulloblastoma, large-cell 20 | 6,241
psoriasis 20 | 6,694
atypical teratoid / rhabdoid tumor 19 | 5,112
primitive neuroectodermal tumor 19 | 3,035
glioblastoma 18 | 5,792
adult high grade glioma 16 | 3,801
group 3 medulloblastoma 15 | 4,104
lung cancer 15 | 4,740
ependymoma 14 | 4,679
Cancer 13 | 2,499
Pick disease 13 | 1,894
Breast cancer 12 | 3,578
Astrocytoma, Pilocytic 11 | 3,081
astrocytic glioma 11 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
oligodendroglioma 10 | 2,850
Autosomal recessive predisposition 9 | 1,442
tuberculosis 9 | 2,010
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
Schizophrenia 7 | 1,160
lung carcinoma 7 | 2,843
malignant mesothelioma 7 | 3,232
non-small cell lung cancer 7 | 2,890
pancreatic cancer 7 | 2,398
ulcerative colitis 7 | 1,819
Intellectual disability 6 | 1,016
Kidney cancer 6 | 2,613
Rheumatoid arthritis 6 | 1,191
colon cancer 6 | 1,478
ductal carcinoma in situ 6 | 1,745
invasive ductal carcinoma 6 | 2,951
pituitary cancer 6 | 1,972
spina bifida 6 | 1,074
breast carcinoma 5 | 1,638
juvenile dermatomyositis 5 | 1,187
progressive supranuclear palsy 5 | 676
subependymal giant cell astrocytoma 5 | 2,287
Alzheimer's disease 4 | 658
Bipolar Disorder 4 | 666
Decreased tendon reflex 4 | 122
Epilepsy 4 | 792
Neurodegenerative disease 4 | 414
Obesity 4 | 678
Prenatal onset 4 | 139
Vascular disease 4 | 319
diabetes mellitus 4 | 1,728
gastric carcinoma 4 | 807
group 4 medulloblastoma 4 | 1,855
primary pancreatic ductal adenocarcinoma 4 | 1,109
Acquired scoliosis 3 | 281
Atopic dermatitis 3 | 952
Autism spectrum disorder 3 | 101
Autistic Disorder 3 | 364
Cerebrovascular disease 3 | 238
Congenital pes cavus 3 | 88
Curvature of spine 3 | 282
Depressive disorder 3 | 409
Distal sensory impairment 3 | 52
Down syndrome 3 | 499
Dull intelligence 3 | 645
Gait abnormality 3 | 135
Hypertension 3 | 396
Liver Cirrhosis, Experimental 3 | 769
Liver cancer 3 | 604
Low intelligence 3 | 645
Mental Depression 3 | 333
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Multiple myeloma 3 | 1,332
Muscle hypotonia 3 | 571
Nerve Degeneration 3 | 121
Neuropathy 3 | 261
Poor school performance 3 | 645
Sensorineural Hearing Loss (disorder) 3 | 284
active Crohn's disease 3 | 922
acute myeloid leukemia 3 | 783
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
astrocytoma 3 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
cystic fibrosis 3 | 1,696
esophageal adenocarcinoma 3 | 737
interstitial cystitis 3 | 2,312
lung adenocarcinoma 3 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
posterior fossa group B ependymoma 3 | 416
tuberculosis and treatment for 6 months 3 | 409
Brain Ischemia 2 | 110
Coronary artery disease 2 | 268
Endometrial cancer 2 | 311
Peripheral vascular disease 2 | 87
Seizures 2 | 596
active ulcerative colitis 2 | 764
fibroadenoma 2 | 559
nasopharyngeal carcinoma 2 | 1,058
pancreatic carcinoma 2 | 562

Tissue

Digestive Tract 37 | 17,369
Endocrine System 37 | 18,159
Liver and Pancreas 37 | 16,750
Male tissues 37 | 17,142
Skin and soft tissues 37 | 17,230
Urinary Tract 37 | 16,678
Blood and immune system 36 | 16,909
Cardiovascular System 36 | 15,192
Female tissues 36 | 17,400
Nervous System 36 | 16,725
Respiratory system 36 | 16,393

Target Family

Non-IDG 23 | 12,091
Enzyme 8 | 4,145
Epigenetic 4 | 242
Ion Channel 1 | 344
Kinase 1 | 634
Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Integrin alpha-2 ITGA2 Tbio Non-IDG -2.58423 335.9 895
Unconventional myosin-VI MYO6 Tbio Non-IDG -1.72509 54.2 108
Transmembrane protein 255B TMEM255B Tdark Non-IDG 0.00000 1.00 19
Kelch domain-containing protein 2 KLHDC2 Tbio Non-IDG -2.82513 669.5 73
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
Histone-lysine N-methyltransferase SETMAR SETMAR Tbio Epigenetic -1.33346 26.5 119
Tumor necrosis factor receptor superfamily member 16 NGFR Tclin Non-IDG -3.06239 1162.1 881
Thyroid hormone receptor beta THRB Tclin Nuclear Receptor -2.82486 627.3 399
SAGA-associated factor 29 SGF29 Tbio Epigenetic -2.78235 590.1 84
Probable E3 ubiquitin-protein ligase HERC3 HERC3 Tdark Enzyme -0.64548 4.44 175