Development Level

Tbio 23 | 10,625
Tchem 5 | 1,890
Tclin 3 | 602
Tdark 3 | 7,003

IMPC Phenotype

tremors 34 | 34
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat-hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

osteosarcoma 20 | 7,933
ovarian cancer 20 | 8,491
medulloblastoma, large-cell 19 | 6,234
psoriasis 18 | 6,685
primitive neuroectodermal tumor 17 | 3,031
glioblastoma 16 | 5,572
atypical teratoid / rhabdoid tumor 14 | 4,369
lung cancer 12 | 4,473
pilocytic astrocytoma 12 | 3,086
Cancer 11 | 2,346
oligodendroglioma 11 | 2,849
Pick disease 10 | 1,893
astrocytic glioma 9 | 2,241
ependymoma 9 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,988
Breast cancer 8 | 3,098
adult high grade glioma 8 | 2,148
pediatric high grade glioma 8 | 2,712
lung carcinoma 7 | 2,844
pancreatic cancer 7 | 2,300
ulcerative colitis 7 | 2,087
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,289
medulloblastoma 6 | 1,524
non-small cell lung cancer 6 | 2,798
sonic hedgehog group medulloblastoma 6 | 1,482
Rheumatoid Arthritis 5 | 1,170
colon cancer 5 | 1,475
ductal carcinoma in situ 5 | 1,745
group 3 medulloblastoma 5 | 2,254
invasive ductal carcinoma 5 | 2,950
malignant mesothelioma 5 | 3,163
pituitary cancer 5 | 1,972
posterior fossa group A ependymoma 5 | 1,511
posterior fossa group B ependymoma 5 | 1,530
subependymal giant cell astrocytoma 5 | 2,287
tuberculosis 5 | 1,563
Alzheimer's disease 4 | 644
Intellectual disability 4 | 573
Neurodegenerative disease 4 | 383
adrenocortical carcinoma 4 | 1,427
astrocytoma 4 | 1,493
breast carcinoma 4 | 1,614
esophageal adenocarcinoma 4 | 737
progressive supranuclear palsy 4 | 674
spina bifida 4 | 1,064
tuberculosis and treatment for 6 months 4 | 686
Atopic dermatitis 3 | 944
Autistic Disorder 3 | 320
Bipolar Disorder 3 | 266
Carcinoma 3 | 2,147
Cerebrovascular disease 3 | 231
Down syndrome 3 | 548
Epilepsy 3 | 346
IGA Glomerulonephritis 3 | 454
Nerve Degeneration 3 | 73
Neuropathy 3 | 210
Schizophrenia 3 | 503
Vascular disease 3 | 281
active Crohn's disease 3 | 918
acute myeloid leukemia 3 | 785
atypical teratoid/rhabdoid tumor 3 | 1,095
cystic fibrosis 3 | 1,670
gastric carcinoma 3 | 832
group 4 medulloblastoma 3 | 1,875
hereditary spastic paraplegia 3 | 313
juvenile dermatomyositis 3 | 1,189
primary pancreatic ductal adenocarcinoma 3 | 1,271
Amyotrophic Lateral Sclerosis 2 | 432
Brain Ischemia 2 | 87
Child Development Disorders, Pervasive 2 | 55
Coronary artery disease 2 | 240
Craniofacial Abnormalities 2 | 147
Endometriosis 2 | 535
Hyperalgesia 2 | 71
Hyperlipidemia 2 | 25
Hypertension 2 | 293
Hypertensive disease 2 | 193
Motor neuron disease 2 | 39
Multiple myeloma 2 | 1,327
Obesity 2 | 616
Peripheral vascular disease 2 | 90
Purpura 2 | 17
Thrombocytopenia 2 | 105
Toxic encephalopathy 2 | 131
acute quadriplegic myopathy 2 | 1,157
aldosterone-producing adenoma 2 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
cutaneous lupus erythematosus 2 | 1,056
cystic fibrosis and chronic rhinosinusitis 2 | 213
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,663
interstitial cystitis 2 | 2,299
lung adenocarcinoma 2 | 2,714
mucosa-associated lymphoid tissue lymphoma 2 | 480
nasopharyngeal carcinoma 2 | 1,056
pancreatic carcinoma 2 | 567
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
periodontitis 2 | 269
primary Sjogren syndrome 2 | 788

Tissue

Cardiovascular System 33 | 17,957
Digestive Tract 33 | 18,472
Liver and Pancreas 33 | 18,135
Male tissues 33 | 17,968
Nervous System 33 | 18,560
Blood and immune system 32 | 17,994
Endocrine System 32 | 18,511
Female tissues 32 | 18,646
Respiratory system 32 | 17,483
Skin and soft tissues 32 | 18,114
Urinary Tract 32 | 18,443

Target Family

Non-IDG 21 | 11,969
Enzyme 6 | 4,146
Epigenetic 3 | 242
Ion Channel 1 | 341
Kinase 1 | 634
Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Synaptojanin-1 SYNJ1 Tbio Non-IDG -1.74048 58.0 91
Integrin alpha-2 ITGA2 Tbio Non-IDG -4.08943 11813.0 639
Myelin-associated glycoprotein MAG Tchem Non-IDG -2.93808 745.2 214
Bromodomain-containing protein 7 BRD7 Tchem Epigenetic -1.60717 49.8 133
Inward rectifier potassium channel 16 KCNJ16 Tbio Ion Channel -1.57364 30.4 111
Tumor necrosis factor receptor superfamily member 16 NGFR Tchem Non-IDG -3.04691 1125.0 687
Prothrombin F2 Tclin Enzyme -4.50962 31685.2 484
Neurexin-1-beta NRXN1 Tbio Non-IDG -1.85998 117.2 148
Ectonucleoside triphosphate diphosphohydrolase 1 ENTPD1 Tbio Enzyme -2.64773 482.4 411
Dual specificity protein kinase CLK1 CLK1 Tchem Kinase -1.92058 79.6 134