Development Level

Tbio 18 | 11,445
Tdark 5 | 6,588
Tchem 4 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

thrombocytosis 27 | 27
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 19 | 11,493
osteosarcoma 16 | 7,950
ovarian cancer 13 | 8,520
psoriasis 9 | 6,694
ependymoma 8 | 4,679
medulloblastoma, large-cell 8 | 6,241
astrocytic glioma 7 | 2,597
atypical teratoid / rhabdoid tumor 7 | 5,112
glioblastoma 7 | 5,792
Astrocytoma, Pilocytic 6 | 3,081
Breast cancer 6 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
oligodendroglioma 6 | 2,850
primitive neuroectodermal tumor 6 | 3,035
Autosomal recessive predisposition 5 | 1,442
group 3 medulloblastoma 5 | 4,104
group 4 medulloblastoma 5 | 1,855
lung adenocarcinoma 5 | 2,716
Cancer 4 | 2,499
Pick disease 4 | 1,894
adult high grade glioma 4 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
juvenile dermatomyositis 4 | 1,187
pancreatic cancer 4 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Epilepsy 3 | 792
Hepatomegaly 3 | 285
Kidney cancer 3 | 2,613
Neurodegenerative disease 3 | 414
acute quadriplegic myopathy 3 | 1,158
diabetes mellitus 3 | 1,728
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
progressive supranuclear palsy 3 | 676
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
Bipolar Disorder 2 | 666
Down syndrome 2 | 499
Dull intelligence 2 | 645
Dysarthria 2 | 192
Gaucher disease type 1 2 | 180
Intellectual disability 2 | 1,016
Liver Cirrhosis, Experimental 2 | 769
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Mucopolysaccharidosis 2 | 26
Parkinson's disease 2 | 392
Polycystic ovary syndrome 2 | 360
Poor school performance 2 | 645
Rheumatoid arthritis 2 | 1,191
Seizures 2 | 596
Splenomegaly 2 | 190
colon cancer 2 | 1,478
dermatomyositis 2 | 966
hereditary spastic paraplegia 2 | 318
invasive ductal carcinoma 2 | 2,951
lung cancer 2 | 4,740
non diabetic and post-ischemic heart failure 2 | 200
pancreatic carcinoma 2 | 562
pituitary cancer 2 | 1,972
tuberculosis and treatment for 6 months 2 | 409
Acanthosis Nigricans 1 | 27
Acute Lung Injury 1 | 22
Autosomal dominant late onset Parkinson disease 1 | 7
Choanal Atresia 1 | 42
Corneal edema 1 | 14
Deep philtrum 1 | 21
Delayed Puberty 1 | 97
Depressed philtrum 1 | 21
Follicular adenoma 1 | 7
Gastritis 1 | 47
Gynecomastia 1 | 64
Hyperkyphosis 1 | 111
Hypertriglyceridemia result 1 | 37
Hypochromic anemia 1 | 9
Kyphosis deformity of spine 1 | 114
Liddle syndrome 1 | 14
Lipodystrophy 1 | 40
Movement disease 1 | 11
Muscle Rigidity 1 | 49
Nephrotic Syndrome 1 | 78
Obesity, Abdominal 1 | 24
Ovarian hyperstimulation syndrome 1 | 19
Overfolded helix 1 | 24
Polydactyly preaxial type 1 1 | 9
Postnatal microcephaly 1 | 24
Postural instability 1 | 19
Progressive microcephaly 1 | 32
Pulmonary emphysema 1 | 48
Rapidly progressive 1 | 27
Rapidly progressive disorder 1 | 27
Retinal disease 1 | 25
Slowed saccades 1 | 12
Static Tremor 1 | 21
Steatohepatitis 1 | 44
severe asthma 1 | 9

Tissue

Digestive Tract 27 | 17,369
Endocrine System 27 | 18,159
Male tissues 27 | 17,142
Nervous System 27 | 16,725
Respiratory system 26 | 16,393
Skin and soft tissues 26 | 17,230
Urinary Tract 26 | 16,678
Female tissues 25 | 17,400
Liver and Pancreas 25 | 16,750
Blood and immune system 24 | 16,909
Cardiovascular System 24 | 15,192

Target Family

Non-IDG 15 | 12,091
Enzyme 5 | 4,145
Transporter 3 | 473
Kinase 2 | 634
Transcription Factor 2 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
High affinity choline transporter 1 SLC5A7 Tchem Transporter -2.99278 986.5 62
RAC-beta serine/threonine-protein kinase AKT2 Tchem Kinase -2.60567 332.5 1173
Trefoil factor 1 TFF1 Tbio Non-IDG -2.40517 263.2 481
Lysosome membrane protein 2 SCARB2 Tbio Non-IDG -2.40121 240.5 282
N-sulphoglucosamine sulphohydrolase SGSH Tbio Enzyme -2.17271 151.8 156
F-box only protein 7 FBXO7 Tbio Non-IDG -2.07231 118.6 100
Histone H2A deubiquitinase MYSM1 MYSM1 Tbio Transcription Factor -1.76987 62.1 184
Coatomer subunit gamma-1 COPG1 Tbio Non-IDG -1.70829 49.0 89
116 kDa U5 small nuclear ribonucleoprotein component EFTUD2 Tbio Non-IDG -1.57287 38.6 177
GRB10-interacting GYF protein 2 GIGYF2 Tchem Non-IDG -1.52965 37.1 43