Development Level

Tbio 18 | 11,445
Tdark 3 | 6,588
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

syndactyly 23 | 23
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 17 | 11,493
ovarian cancer 14 | 8,520
osteosarcoma 11 | 7,950
glioblastoma 8 | 5,792
medulloblastoma, large-cell 8 | 6,241
atypical teratoid / rhabdoid tumor 7 | 5,112
group 3 medulloblastoma 7 | 4,104
psoriasis 7 | 6,694
Breast cancer 6 | 3,578
lung cancer 6 | 4,740
adult high grade glioma 5 | 3,801
astrocytic glioma 5 | 2,597
ependymoma 5 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
invasive ductal carcinoma 5 | 2,951
lung adenocarcinoma 5 | 2,716
malignant mesothelioma 5 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
primitive neuroectodermal tumor 5 | 3,035
tuberculosis 5 | 2,010
Multiple myeloma 4 | 1,332
Pick disease 4 | 1,894
ductal carcinoma in situ 4 | 1,745
group 4 medulloblastoma 4 | 1,855
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
Astrocytoma, Pilocytic 3 | 3,081
Cancer 3 | 2,499
Kidney cancer 3 | 2,613
Melanoma 3 | 711
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
breast carcinoma 3 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
juvenile dermatomyositis 3 | 1,187
Alzheimer's disease 2 | 658
Amyotrophic lateral sclerosis 2 | 451
Fetal Growth Retardation 2 | 189
Hypoplastic mandible condyle 2 | 275
Infant, Small for Gestational Age 2 | 176
Intrauterine retardation 2 | 176
Large auricle 2 | 87
Large dysplastic ears 2 | 87
Large pinnae 2 | 87
Large prominent ears 2 | 87
Large protruding ears 2 | 87
Large, floppy ears 2 | 87
Liver Cirrhosis, Experimental 2 | 769
Macrotia 2 | 87
Mandibular hypoplasia 2 | 275
Micrognathism 2 | 275
Microphthalmia 2 | 76
Orbital separation excessive 2 | 244
Skin cancer 2 | 469
Syndactyly 2 | 88
Waldenstrons macroglobulinemia 2 | 765
acute myeloid leukemia 2 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
inflammatory breast cancer 2 | 286
lung carcinoma 2 | 2,843
nasopharyngeal carcinoma 2 | 1,058
pancreatic cancer 2 | 2,398
pituitary cancer 2 | 1,972
sarcoidosis 2 | 370
sonic hedgehog group medulloblastoma 2 | 467
ulcerative colitis 2 | 1,819
Aphasia 1 | 26
Asphyxiating thoracic dystrophy 1 | 44
Basal cell carcinoma 1 | 54
Carcinoma, Basal Cell 1 | 28
Choanal Atresia 1 | 42
Choanal stenosis 1 | 11
Cocaine Dependence 1 | 51
Deglutition Disorders 1 | 132
Dental abnormalities 1 | 60
Edema 1 | 81
Fibrosis 1 | 44
Fused vertebrae 1 | 25
Intracranial hypotension 1 | 10
Leiomyoma 1 | 32
Matthew-Wood syndrome 1 | 11
Myasthenias 1 | 8
Nicotine dependence 1 | 54
Non-immune hydrops fetalis 1 | 11
Ophthalmoparesis 1 | 11
Pitt-Hopkins syndrome 1 | 20
Pulmonary emphysema 1 | 48
Relative macrocephaly 1 | 12
Short to absent middle phalanges 1 | 5
Spinal fusion 1 | 25
Subdural empyema 1 | 7
Tooth Abnormalities 1 | 69
Usher syndrome type 1C 1 | 3
Uterine fibroid 1 | 28
Varicocele 1 | 26
Vertebral body fusion 1 | 25

Tissue

Endocrine System 23 | 18,159
Skin and soft tissues 23 | 17,230
Blood and immune system 22 | 16,909
Digestive Tract 22 | 17,369
Female tissues 22 | 17,400
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Respiratory system 22 | 16,393
Urinary Tract 22 | 16,678
Cardiovascular System 21 | 15,192
Nervous System 21 | 16,725

Target Family

Non-IDG 12 | 12,091
Enzyme 7 | 4,145
Transcription Factor 2 | 1,400
Ion Channel 1 | 344
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras-related protein Rab-19 RAB19 Tdark Enzyme -0.54731 3.31 75
Acetylcholine receptor subunit alpha CHRNA1 Tclin Ion Channel -1.66400 41.7 307
Pleckstrin homology domain-containing family G member 3 PLEKHG3 Tdark Non-IDG -0.40654 2.48 66
BTB/POZ domain-containing protein KCTD15 KCTD15 Tbio Non-IDG -1.04860 11.7 176
Phosphatidylserine synthase 1 PTDSS1 Tbio Enzyme -1.93971 87.1 109
Synaptopodin-2 SYNPO2 Tbio Non-IDG -1.31714 27.9 42
Serine/threonine-protein phosphatase 6 catalytic subunit PPP6C Tbio Enzyme -2.41091 208.5 230
Serine dehydratase-like SDSL Tbio Enzyme -2.81127 638.6 190
Transmembrane protein 132A TMEM132A Tdark Non-IDG -0.23045 2.47 54
Protein YIPF5 YIPF5 Tbio Non-IDG -1.27388 17.9 90