Development Level

Tbio 42 | 11,445
Tchem 8 | 1,598
Tdark 7 | 6,588
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

small testis 58 | 58
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

ovarian cancer 37 | 8,520
Carcinoma 35 | 11,493
osteosarcoma 33 | 7,950
glioblastoma 24 | 5,792
psoriasis 23 | 6,694
medulloblastoma, large-cell 22 | 6,241
atypical teratoid / rhabdoid tumor 18 | 5,112
ependymoma 18 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
malignant mesothelioma 16 | 3,232
adult high grade glioma 15 | 3,801
oligodendroglioma 15 | 2,850
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
lung cancer 14 | 4,740
Breast cancer 13 | 3,578
group 3 medulloblastoma 12 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
Astrocytoma, Pilocytic 11 | 3,081
Cancer 11 | 2,499
Kidney cancer 11 | 2,613
astrocytic glioma 11 | 2,597
lung carcinoma 11 | 2,843
lung adenocarcinoma 10 | 2,716
non-small cell lung cancer 10 | 2,890
pituitary cancer 10 | 1,972
primitive neuroectodermal tumor 10 | 3,035
spina bifida 10 | 1,074
subependymal giant cell astrocytoma 10 | 2,287
Autosomal recessive predisposition 9 | 1,442
group 4 medulloblastoma 9 | 1,855
interstitial cystitis 9 | 2,312
ulcerative colitis 9 | 1,819
Atopic dermatitis 8 | 952
invasive ductal carcinoma 8 | 2,951
Pick disease 7 | 1,894
Rheumatoid arthritis 7 | 1,191
breast carcinoma 7 | 1,638
tuberculosis 7 | 2,010
Acquired metabolic disease 6 | 336
Obesity 6 | 678
diabetes mellitus 6 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
primary pancreatic ductal adenocarcinoma 6 | 1,109
Muscle hypotonia 5 | 571
Prostatic Neoplasms 5 | 495
Schizophrenia 5 | 1,160
adrenocortical carcinoma 5 | 1,428
astrocytoma 5 | 1,146
atypical teratoid/rhabdoid tumor 5 | 357
cutaneous lupus erythematosus 5 | 1,057
ductal carcinoma in situ 5 | 1,745
pancreatic cancer 5 | 2,398
Bipolar Disorder 4 | 666
Epilepsy 4 | 792
Liver Cirrhosis, Experimental 4 | 769
Multiple myeloma 4 | 1,332
Neurodegenerative disease 4 | 414
cystic fibrosis 4 | 1,696
juvenile dermatomyositis 4 | 1,187
pediatric high grade glioma 4 | 1,064
primary Sjogren syndrome 4 | 735
Adenoma 3 | 167
Arthritis, Rheumatoid 3 | 174
Attention deficit hyperactivity disorder 3 | 278
Cerebellar Ataxia 3 | 304
Cognitive delay 3 | 608
Colonic Neoplasms 3 | 142
Congenital Heart Defects 3 | 58
Craniofacial Abnormalities 3 | 151
Dull intelligence 3 | 645
Global developmental delay 3 | 608
Heart Defects, Congenital 3 | 37
Hypertensive disease 3 | 292
Intellectual disability 3 | 1,016
Kidney disease 3 | 430
Liver cancer 3 | 604
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Poor school performance 3 | 645
Reperfusion Injury 3 | 86
Retinitis Pigmentosa 3 | 226
Seizures 3 | 596
Short stature 3 | 531
Stomach Neoplasms 3 | 300
active Crohn's disease 3 | 922
colon cancer 3 | 1,478
dermatomyositis 3 | 966
posterior fossa group A ependymoma 3 | 468
progressive supranuclear palsy 3 | 676
sonic hedgehog group medulloblastoma 3 | 467
Depressive disorder 2 | 409
Down syndrome 2 | 499
Endometriosis 2 | 540
Juvenile arthritis 2 | 126
Mental Depression 2 | 333
acute quadriplegic myopathy 2 | 1,158
chronic rhinosinusitis 2 | 512
esophageal adenocarcinoma 2 | 737

Tissue

Endocrine System 57 | 18,159
Female tissues 56 | 17,400
Skin and soft tissues 56 | 17,230
Blood and immune system 55 | 16,909
Digestive Tract 55 | 17,369
Liver and Pancreas 55 | 16,750
Male tissues 55 | 17,142
Nervous System 54 | 16,725
Respiratory system 53 | 16,393
Urinary Tract 53 | 16,678
Cardiovascular System 50 | 15,192

Target Family

Non-IDG 31 | 12,091
Enzyme 13 | 4,145
Kinase 5 | 634
Epigenetic 3 | 242
Transcription Factor 3 | 1,400
GPCR 1 | 408
Ion Channel 1 | 344
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Relaxin receptor 2 RXFP2 Tbio GPCR -1.97913 85.3 207
Mitotic spindle assembly checkpoint protein MAD1 MAD1L1 Tbio Non-IDG -1.17500 13.6 283
SLIT and NTRK-like protein 1 SLITRK1 Tbio Non-IDG -2.74906 555.5 206
Folate receptor alpha FOLR1 Tchem Non-IDG -2.33242 206.1 303
Phosphate carrier protein, mitochondrial SLC25A3 Tbio Transporter -2.85426 703.4 33
Dysbindin domain-containing protein 2 DBNDD2 Tdark Non-IDG 0.23 0.66 28
Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 Tbio Ion Channel -1.74365 53.9 92
Tyrosine-protein kinase Blk BLK Tchem Kinase -1.88753 81.6 418
Cytoglobin CYGB Tbio Non-IDG -3.10582 1269.7 202
Platelet glycoprotein Ib beta chain GP1BB Tbio Non-IDG -1.79873 57.4 87