Development Level

Tbio 51 | 11,445
Tdark 13 | 6,588
Tchem 7 | 1,598
Tclin 3 | 613

Collection

RFA-RM-18-021 3 | 328
Ion Channel: IDG Consortium (T... 2 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

small superior vagus ganglion 74 | 74
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 37 | 11,493
ovarian cancer 35 | 8,520
osteosarcoma 34 | 7,950
psoriasis 27 | 6,694
atypical teratoid / rhabdoid tumor 21 | 5,112
glioblastoma 21 | 5,792
medulloblastoma, large-cell 21 | 6,241
malignant mesothelioma 18 | 3,232
ependymoma 17 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
group 3 medulloblastoma 16 | 4,104
interstitial cystitis 16 | 2,312
Autosomal recessive predisposition 15 | 1,442
Cancer 15 | 2,499
lung cancer 15 | 4,740
non-small cell lung cancer 15 | 2,890
adult high grade glioma 14 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
invasive ductal carcinoma 14 | 2,951
lung carcinoma 14 | 2,843
astrocytic glioma 12 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
lung adenocarcinoma 12 | 2,716
Breast cancer 11 | 3,578
group 4 medulloblastoma 11 | 1,855
Astrocytoma, Pilocytic 10 | 3,081
Rheumatoid arthritis 10 | 1,191
oligodendroglioma 10 | 2,850
Kidney cancer 9 | 2,613
Schizophrenia 9 | 1,160
cutaneous lupus erythematosus 9 | 1,057
pancreatic cancer 9 | 2,398
primitive neuroectodermal tumor 9 | 3,035
subependymal giant cell astrocytoma 9 | 2,287
ulcerative colitis 9 | 1,819
Melanoma 8 | 711
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Obesity 7 | 678
Pick disease 7 | 1,894
cystic fibrosis 7 | 1,696
diabetes mellitus 7 | 1,728
spina bifida 7 | 1,074
Short stature 6 | 531
acute quadriplegic myopathy 6 | 1,158
pituitary cancer 6 | 1,972
tuberculosis 6 | 2,010
Anemia 5 | 365
Atopic dermatitis 5 | 952
Dull intelligence 5 | 645
Intellectual disability 5 | 1,016
Kidney disease 5 | 430
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Muscle hypotonia 5 | 571
Pancreatitis 5 | 123
Poor school performance 5 | 645
adrenocortical carcinoma 5 | 1,428
breast carcinoma 5 | 1,638
colon cancer 5 | 1,478
juvenile dermatomyositis 5 | 1,187
medulloblastoma 5 | 720
non primary Sjogren syndrome sicca 5 | 891
primary Sjogren syndrome 5 | 735
Arthritis 4 | 290
Asthma 4 | 385
Atherosclerosis 4 | 291
Cognitive delay 4 | 608
Craniofacial Abnormalities 4 | 151
Global developmental delay 4 | 608
Hypersensitivity reaction type II disease 4 | 253
Hypertension 4 | 396
Hypertensive disease 4 | 292
Hypotrophic malar bone 4 | 129
Kidney Diseases 4 | 114
Malar flattening 4 | 129
Mental and motor retardation 4 | 608
Osteoporosis 4 | 363
Prostatic Neoplasms 4 | 495
active Crohn's disease 4 | 922
acute myeloid leukemia 4 | 783
ductal carcinoma in situ 4 | 1,745
fibroadenoma 4 | 559
pancreatic carcinoma 4 | 562
periodontitis 4 | 293
posterior fossa group A ependymoma 4 | 468
Alzheimer's disease 3 | 658
Bipolar Disorder 3 | 666
Carcinoma, Hepatocellular 3 | 228
Cerebrovascular disease 3 | 238
Coronary artery disease 3 | 268
Epilepsy 3 | 792
Liver carcinoma 3 | 240
Multiple Sclerosis 3 | 540
Seizures 3 | 596
Stomach Neoplasms 3 | 300
astrocytoma 3 | 1,146
gastric cancer 3 | 459
nasopharyngeal carcinoma 3 | 1,058
pediatric high grade glioma 3 | 1,064

Tissue

Digestive Tract 72 | 17,369
Male tissues 72 | 17,142
Blood and immune system 71 | 16,909
Female tissues 71 | 17,400
Skin and soft tissues 71 | 17,230
Endocrine System 70 | 18,159
Nervous System 69 | 16,725
Respiratory system 69 | 16,393
Urinary Tract 68 | 16,678
Liver and Pancreas 67 | 16,750
Cardiovascular System 60 | 15,192

Target Family

Non-IDG 41 | 12,091
Enzyme 17 | 4,145
Transcription Factor 5 | 1,400
GPCR 3 | 408
Ion Channel 3 | 344
Kinase 3 | 634
Epigenetic 1 | 242
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytochrome c oxidase assembly factor 5 COA5 Tdark Enzyme -0.77512 6.90 3
Transmembrane protein 160 TMEM160 Tdark Non-IDG 0.38 0.37 10
Poly(A) RNA polymerase, mitochondrial MTPAP Tbio Enzyme -1.36829 24.0 68
Steroid receptor RNA activator 1 SRA1 Tbio Non-IDG -2.78991 595.4 160
Poly(ADP-ribose) glycohydrolase PARG Tchem Enzyme -2.32776 229.4 126
Cell surface A33 antigen GPA33 Tbio Non-IDG -1.79665 56.9 248
Cystatin-C CST3 Tbio Non-IDG -3.52815 3278.8 866
SKI/DACH domain-containing protein 1 SKIDA1 Tdark Non-IDG -0.23045 1.67 0
Testis development-related protein TDRP Tbio Non-IDG -0.59437 4.93 39
Brain mitochondrial carrier protein 1 SLC25A14 Tbio Transporter -1.45184 29.0 51