Development Level

Tbio 12 | 10,625
Tdark 4 | 7,003
Tchem 3 | 1,890
Tclin 1 | 602

Collection

Ion Channel: IDG Consortium (Targets) 1 | 102

IMPC Phenotype

small superior vagus ganglion 20 | 20
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat-hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

ovarian cancer 9 | 8,491
osteosarcoma 8 | 7,933
psoriasis 8 | 6,685
glioblastoma 7 | 5,572
interstitial cystitis 7 | 2,299
Cancer 5 | 2,346
astrocytic glioma 5 | 2,241
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
malignant mesothelioma 5 | 3,163
medulloblastoma, large-cell 5 | 6,234
atypical teratoid / rhabdoid tumor 4 | 4,369
lung cancer 4 | 4,473
non-small cell lung cancer 4 | 2,798
oligodendroglioma 4 | 2,849
ulcerative colitis 4 | 2,087
Rheumatoid Arthritis 3 | 1,170
active Crohn's disease 3 | 918
atypical teratoid/rhabdoid tumor 3 | 1,095
group 3 medulloblastoma 3 | 2,254
group 4 medulloblastoma 3 | 1,875
lung carcinoma 3 | 2,844
posterior fossa group A ependymoma 3 | 1,511
Breast cancer 2 | 3,098
Craniofacial Abnormalities 2 | 147
Polydactyly 2 | 93
Schizophrenia 2 | 503
acute myeloid leukemia 2 | 785
adult high grade glioma 2 | 2,148
astrocytoma 2 | 1,493
cutaneous lupus erythematosus 2 | 1,056
ependymoma 2 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
non primary Sjogren syndrome sicca 2 | 840
pancreatic carcinoma 2 | 567
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
pediatric high grade glioma 2 | 2,712
posterior fossa group B ependymoma 2 | 1,530
primitive neuroectodermal tumor 2 | 3,031
spina bifida 2 | 1,064
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 1,563
ADULT syndrome 1 | 9
Ameloblastoma 1 | 25
Amenorrhea 1 | 60
Anemia 1 | 252
Apraxia 1 | 25
Asphyxiating thoracic dystrophy 1 | 34
Bipolar Disorder 1 | 266
Carcinoma of pancreas 1 | 5
Cardioencephalomyopathy, fatal infantile, due to cytochrome c oxidase deficiency 3 1 | 1
Choanal atresia 1 | 19
Cholera 1 | 33
Chromosome 2q32-q33 deletion syndrome 1 | 5
Cleft Lip 1 | 91
Cleft palate 1 | 125
Clubfoot 1 | 35
Coloboma 1 | 52
Congenital heart disease 1 | 63
Cystic kidney disease 1 | 26
Ectropion 1 | 18
Fundus dystrophy 1 | 77
Gastrointestinal system disease 1 | 50
Goldenhar syndrome 1 | 19
Hermansky-Pudlak syndrome 1 | 43
Hypogonadism 1 | 70
Hypogonadotropic hypogonadism 1 | 20
Hypogonadotropic hypogonadism 7 with or without anosmia 1 | 6
Hypogonadotropism 1 | 9
Hypohidrosis 1 | 13
Hypospadias 1 | 65
Idiopathic hypogonadotropic hypogonadism 1 | 9
Imperforate anus 1 | 14
Joubert syndrome 4 1 | 3
Kidney Diseases 1 | 86
Klinefelter's syndrome 1 | 59
Leukopenia 1 | 42
Lung Neoplasms 1 | 171
Lymphatic system disease 1 | 14
Macroglobulinemia 1 | 17
Melanoma 1 | 261
Nasopharynx carcinoma 1 | 19
Neoplasm Metastasis 1 | 138
Neutropenia 1 | 78
Opitz-GBBB syndrome 1 | 19
Popliteal pterygium syndrome 1 | 6
Primary immunodeficiency disease 1 | 52
Prostate leiomyosarcoma 1 | 2
Refractive error 1 | 43
Renal agenesis 1 | 25
Severe congenital neutropenia 1 | 10
Skin disease 1 | 65
Small cell carcinoma of lung 1 | 45
Syndactyly 1 | 56
Thrombocytopenia 1 | 105
Tooth agenesis 1 | 38
Type 1 diabetes mellitus 1 | 104
Wolf-Hirschhorn syndrome 1 | 32
cytochrome-c oxidase deficiency disease 1 | 19
end stage renal failure 1 | 7
interstitial lung disease 1 | 292

Tissue

Cardiovascular System 20 | 17,957
Liver and Pancreas 20 | 18,135
Nervous System 20 | 18,560
Blood and immune system 19 | 17,994
Digestive Tract 19 | 18,472
Endocrine System 19 | 18,511
Female tissues 19 | 18,646
Male tissues 19 | 17,968
Skin and soft tissues 19 | 18,114
Urinary Tract 19 | 18,443
Respiratory system 18 | 17,483

Target Family

Non-IDG 12 | 11,969
Enzyme 3 | 4,146
Kinase 2 | 634
GPCR 1 | 408
Ion Channel 1 | 341
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Testis development-related protein TDRP Tbio Non-IDG -0.62632 5.48 36
FAS-associated death domain protein FADD Tbio Non-IDG -2.68548 451.9 595
Activin receptor type-1B ACVR1B Tchem Kinase -1.98732 76.4 385
KiSS-1 receptor KISS1R Tchem GPCR -2.42416 253.1 220
Nephrocystin-1 NPHP1 Tbio Non-IDG -1.74646 50.8 88
Dysbindin DTNBP1 Tbio Non-IDG -2.42167 273.0 277
DNA-binding protein SATB2 SATB2 Tbio Transcription Factor -2.84908 654.1 179
Granulocyte colony-stimulating factor receptor CSF3R Tclin Non-IDG -2.20449 172.7 358
SKI/DACH domain-containing protein 1 SKIDA1 Tdark Non-IDG -0.07918 1.17 0
Steroid receptor RNA activator 1 SRA1 Tbio Non-IDG -2.78708 588.5 144