Development Level

Tbio 9 | 11,445
Tdark 5 | 6,588
Tchem 4 | 1,598
Tclin 1 | 613

IMPC Phenotype

small spleen 19 | 19
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 13 | 11,493
osteosarcoma 11 | 7,950
glioblastoma 9 | 5,792
ovarian cancer 9 | 8,520
psoriasis 9 | 6,694
atypical teratoid / rhabdoid tumor 8 | 5,112
group 3 medulloblastoma 8 | 4,104
medulloblastoma, large-cell 8 | 6,241
adult high grade glioma 7 | 3,801
ependymoma 6 | 4,679
malignant mesothelioma 6 | 3,232
Astrocytoma, Pilocytic 5 | 3,081
Cancer 5 | 2,499
lung cancer 5 | 4,740
primitive neuroectodermal tumor 5 | 3,035
Autosomal recessive predisposition 4 | 1,442
astrocytoma 4 | 1,146
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
non-small cell lung cancer 4 | 2,890
Breast cancer 3 | 3,578
Multiple myeloma 3 | 1,332
acute quadriplegic myopathy 3 | 1,158
colon cancer 3 | 1,478
diabetes mellitus 3 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
juvenile dermatomyositis 3 | 1,187
lung adenocarcinoma 3 | 2,716
Asthma 2 | 385
Breast Neoplasms 2 | 445
Disease Progression 2 | 136
Failure to gain weight 2 | 365
Mammary Neoplasms 2 | 425
Muscle hypotonia 2 | 571
Neoplasm Invasiveness 2 | 161
Neoplasm Metastasis 2 | 168
Pediatric failure to thrive 2 | 365
Pick disease 2 | 1,894
Systemic lupus erythematosus 2 | 194
Waldenstrons macroglobulinemia 2 | 765
ductal carcinoma in situ 2 | 1,745
interstitial cystitis 2 | 2,312
lung carcinoma 2 | 2,843
nephrosclerosis 2 | 333
non primary Sjogren syndrome sicca 2 | 891
oligodendroglioma 2 | 2,850
pediatric high grade glioma 2 | 1,064
primary Sjogren syndrome 2 | 735
Acne 1 | 52
Alkaline phosphatase serum increased 1 | 29
Amenorrhea 1 | 58
Androgen insensitivity syndrome 1 | 12
Anovulation 1 | 21
Ascariasis 1 | 7
Carcinoma, Non-Small-Cell Lung 1 | 107
Congenital sensorineural hearing loss 1 | 12
Defective enamel matrix 1 | 35
Delayed epiphyseal ossification 1 | 10
Delayed maturation of end part of long bone 1 | 10
Dental Enamel Hypoplasia 1 | 43
DiGeorge syndrome 1 | 47
Dysplasia of tooth enamel 1 | 35
Echinococcosis 1 | 26
Elevated gonadotropins 1 | 15
Eosinophilic meningitis 1 | 5
Femoral bowing 1 | 20
Genu varum 1 | 29
Hereditary renal cell carcinoma 1 | 3
Hypercalcemia 1 | 59
Increased serum parathyroid hormone 1 | 14
Irritation - emotion 1 | 68
Lactocele 1 | 3
Leydig Cell Hypoplasia, Type 1 1 | 2
McCune Albright syndrome 1 | 19
Metabolic acidosis 1 | 90
Metaphyseal irregularity 1 | 23
Neurodegenerative Diseases 1 | 38
Nonorganic psychosis 1 | 84
Ovarian hyperstimulation syndrome 1 | 19
Piebaldism 1 | 15
Precocious Puberty 1 | 28
Precocious Puberty, Male-Limited 1 | 2
Premature canities 1 | 24
Premature ovarian failure 1 | 65
Primary hypogonadism 1 | 37
Pseudohermaphroditism 1 | 16
Respiratory Distress Syndrome, Adult 1 | 40
Rhinitis 1 | 54
Sick sinus syndrome 1 | 15
Small testicle 1 | 75
Sotos syndrome 1 | 13
Spinocerebellar ataxia type 20 1 | 1
Thin bony cortex 1 | 9
Thin dental enamel 1 | 35
Thyroid cancer, papillary 1 | 14
Velocardiofacial syndrome 1 | 46
Waardenburg's syndrome 1 | 17
Wolf-Hirschhorn syndrome 1 | 32
hypopigmented skin patch 1 | 59

Tissue

Digestive Tract 18 | 17,369
Endocrine System 18 | 18,159
Skin and soft tissues 18 | 17,230
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Male tissues 17 | 17,142
Urinary Tract 17 | 16,678
Blood and immune system 16 | 16,909
Nervous System 16 | 16,725
Respiratory system 16 | 16,393
Cardiovascular System 15 | 15,192

Target Family

Non-IDG 9 | 12,091
Enzyme 5 | 4,145
Epigenetic 2 | 242
GPCR 1 | 408
Transcription Factor 1 | 1,400
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Septin-5 SEPT5 Tbio Non-IDG -1.71017 49.4 178
Sn1-specific diacylglycerol lipase alpha DAGLA Tchem Enzyme -1.11500 11.4 129
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit DDOST Tchem Enzyme -1.60313 44.1 140
Histone-lysine N-methyltransferase NSD3 NSD3 Tbio Epigenetic -1.36629 23.0 234
SKI/DACH domain-containing protein 1 SKIDA1 Tdark Non-IDG -0.23045 1.67 0
Transmembrane protein 248 TMEM248 Tdark Non-IDG 0.00000 47
Zinc finger protein SNAI2 SNAI2 Tbio Transcription Factor -3.25853 1689.4 685
COP9 signalosome complex subunit 7a COPS7A Tbio Non-IDG -1.50943 32.2 154
Leucine-rich repeat-containing protein 30 LRRC30 Tdark Non-IDG 0.00000 5
Coiled-coil domain-containing protein 124 CCDC124 Tdark Non-IDG 0.27 0.87 53