Development Level

Tbio 2 | 11,445
Tchem 2 | 1,598
Tclin 2 | 613
Tdark 2 | 6,588

IMPC Phenotype

small liver 8 | 8
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 6 | 11,493
psoriasis 4 | 6,694
atypical teratoid / rhabdoid tumor 3 | 5,112
group 3 medulloblastoma 3 | 4,104
lung cancer 3 | 4,740
medulloblastoma, large-cell 3 | 6,241
Kidney cancer 2 | 2,613
Liver cancer 2 | 604
Neurodegenerative disease 2 | 414
adult high grade glioma 2 | 3,801
malignant mesothelioma 2 | 3,232
ovarian cancer 2 | 8,520
subependymal giant cell astrocytoma 2 | 2,287
46, XY Disorders of Sex Development 1 | 3
Absence seizure 1 | 12
Acne 1 | 52
Advanced bone age 1 | 35
Amenorrhea 1 | 58
Androgen insensitivity syndrome 1 | 12
Anovulation 1 | 21
Astrocytoma, Pilocytic 1 | 3,081
Autosomal dominant cerebellar ataxia 1 | 33
Autosomal recessive predisposition 1 | 1,442
Breast cancer 1 | 3,578
CLEFT PALATE, PSYCHOMOTOR RETARDATION, AND DISTINCTIVE FACIAL FEATURES 1 | 1
Cancer 1 | 2,499
Cannabis dependence 1 | 23
Carcinoma, Non-Small-Cell Lung 1 | 107
Chronic obstructive pulmonary disease 1 | 184
Colonic Neoplasms 1 | 142
Congenital adrenal hyperplasia 1 | 73
Critical Illness 1 | 2
Disease Progression 1 | 136
Disorders of Sex Development 1 | 5
Elevated gonadotropins 1 | 15
Epilepsy 1 | 792
Familial Testotoxicosis 1 | 3
Gaucher disease type 1 1 | 180
Hair shaft abnormalities 1 | 30
Hyperplasia 1 | 27
Hypogonadism 1 | 173
Hypospadias 1 | 53
Increased size of penis 1 | 7
Infertility 1 | 188
Infertility, Male 1 | 46
Lactocele 1 | 3
Leydig Cell Hypoplasia 1 | 1
Leydig Cell Hypoplasia, Type 1 1 | 2
Leydig cell agenesis 1 | 1
Leydig cell tumor 1 | 9
Male infertility 1 | 206
McCune Albright syndrome 1 | 19
Melanoma 1 | 711
Multiple myeloma 1 | 1,332
NEURONOPATHY, DISTAL HEREDITARY MOTOR, TYPE IID 1 | 1
Neoplasm Invasiveness 1 | 161
Neuronopathy, Distal Hereditary Motor, Type 2D 1 | 1
Neuropathy 1 | 261
Obesity 1 | 678
Onchocerciasis 1 | 10
Ovarian hyperstimulation syndrome 1 | 19
Polycystic kidney disease 1 1 | 21
Polycystic ovary syndrome 1 | 360
Precocious Puberty 1 | 28
Precocious Puberty, Male-Limited 1 | 2
Precocious puberty in males 1 | 2
Premature ovarian failure 1 | 65
Primary hypogonadism 1 | 37
Pseudohermaphroditism 1 | 16
Rheumatoid arthritis 1 | 1,191
Schizophrenia 1 | 1,160
Skin cancer 1 | 469
Small testicle 1 | 75
Spinocerebellar ataxia type 20 1 | 1
Tall stature 1 | 34
Testotoxicosis 1 | 1
astrocytic glioma 1 | 2,597
astrocytoma 1 | 1,146
colon cancer 1 | 1,478
dermatomyositis 1 | 966
ductal carcinoma in situ 1 | 1,745
ependymoma 1 | 4,679
esophageal adenocarcinoma 1 | 737
glioblastoma 1 | 5,792
group 4 medulloblastoma 1 | 1,855
hair abnormalities (non-specific) 1 | 30
lung carcinoma 1 | 2,843
non primary Sjogren syndrome sicca 1 | 891
non-small cell lung carcinoma 1 | 317
osteosarcoma 1 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
primitive neuroectodermal tumor 1 | 3,035
spina bifida 1 | 1,074
tuberculosis and treatment for 6 months 1 | 409

Tissue

Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Urinary Tract 8 | 16,678
Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Male tissues 6 | 17,142

Target Family

Non-IDG 3 | 12,091
Enzyme 2 | 4,145
Epigenetic 1 | 242
GPCR 1 | 408
Ion Channel 1 | 344

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sn1-specific diacylglycerol lipase alpha DAGLA Tchem Enzyme -1.11500 11.4 129
Ubiquitin-conjugating enzyme E2 G1 UBE2G1 Tbio Non-IDG -0.84360 6.17 155
Coiled-coil domain-containing protein 124 CCDC124 Tdark Non-IDG 0.27 0.87 53
Lutropin-choriogonadotropic hormone receptor LHCGR Tclin GPCR -2.58909 376.4 243
F-box only protein 38 FBXO38 Tbio Non-IDG -1.46495 29.4 45
Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I Tclin Ion Channel -1.95446 85.6 79
Lysine-specific histone demethylase 1A KDM1A Tchem Epigenetic -2.68692 516.3 473
E3 ubiquitin-protein ligase HECTD3 HECTD3 Tdark Enzyme 0.85 0.41 88