Development Level

Tchem 3 | 1,598
Tclin 3 | 613
Tbio 2 | 11,445
Tdark 2 | 6,588

IMPC Phenotype

small heart 10 | 10
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 8 | 11,493
psoriasis 5 | 6,694
medulloblastoma, large-cell 4 | 6,241
osteosarcoma 4 | 7,950
adult high grade glioma 3 | 3,801
atypical teratoid / rhabdoid tumor 3 | 5,112
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
lung cancer 3 | 4,740
Astrocytoma, Pilocytic 2 | 3,081
Autosomal recessive predisposition 2 | 1,442
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Obesity 2 | 678
Schizophrenia 2 | 1,160
colon cancer 2 | 1,478
ependymoma 2 | 4,679
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
subependymal giant cell astrocytoma 2 | 2,287
'Bulging' epiphyses 1 | 3
Abdominal wall muscle weakness 1 | 6
Absence seizure 1 | 12
Acne 1 | 52
Addison's disease 1 | 31
Allergic conjunctivitis 1 | 22
Amenorrhea 1 | 58
Androgen insensitivity syndrome 1 | 12
Anovulation 1 | 21
Binge eating disorder 1 | 3
Bipolar affective disorder, current episode depression 1 | 6
Brain cancer 1 | 30
Congenital hereditary endothelial dystrophy of cornea 1 | 8
Defective enamel matrix 1 | 35
Delayed epiphyseal ossification 1 | 10
Delayed maturation of end part of long bone 1 | 10
Dental Enamel Hypoplasia 1 | 43
Depressive Disorder, Treatment-Resistant 1 | 6
Difficulty standing 1 | 3
Disorders of Sex Development 1 | 5
Dysplasia of tooth enamel 1 | 35
Elevated gonadotropins 1 | 15
Enlargement of the ankles 1 | 3
Enlargement of the costochondral junction 1 | 4
Enlargement of the wrists 1 | 5
Female stress incontinence 1 | 7
Femoral bowing 1 | 20
Fibroid Tumor 1 | 6
Fibular bowing 1 | 5
Generalized aminoaciduria 1 | 9
Headache disorder 1 | 19
Hyperekplexia 1 | 16
Hyperparathyroidism, Secondary 1 | 7
Hypertensive disorder 1 | 56
Hypervitaminosis D 1 | 8
Increased serum parathyroid hormone 1 | 14
Increased size of penis 1 | 7
Influenza-like symptoms 1 | 16
Insomnia 1 | 20
Irritation - emotion 1 | 68
Lactocele 1 | 3
Leiomyoma 1 | 32
Leydig cell tumor 1 | 9
Lichen simplex chronicus 1 | 7
Low blood pressure 1 | 9
McCune Albright syndrome 1 | 19
Metaphyseal irregularity 1 | 23
Mixed anxiety and depressive disorder 1 | 12
Nasal discharge 1 | 24
Nicotine dependence 1 | 54
Nocturnal enuresis 1 | 6
Nonorganic psychosis 1 | 84
Ocular hyperemia 1 | 2
Oppositional defiant disorder 1 | 17
Ovarian hyperstimulation syndrome 1 | 19
Pain 1 | 103
Polymyositis 1 | 5
Precocious Puberty 1 | 28
Precocious puberty in males 1 | 2
Premature ovarian failure 1 | 65
Prevention of Ventricular Fibrillation 1 | 2
Primary hypogonadism 1 | 37
Protuberant abdomen 1 | 16
Pseudohermaphroditism 1 | 16
Recurrent depression 1 | 9
Seasonal affective disorder 1 | 28
Seasonal allergic rhinitis 1 | 9
Severe major depression with psychotic features 1 | 9
Sick sinus syndrome 1 | 15
Sinus headache 1 | 16
Smoking cessation assistance 1 | 8
Social phobia 1 | 10
Sparse bone trabeculae 1 | 3
Spinocerebellar ataxia type 20 1 | 1
Thin dental enamel 1 | 35
Tibial bowing 1 | 19
Vasomotor rhinitis 1 | 12
Widely patent fontanels and sutures 1 | 12
obsessive-compulsive disorder 1 | 61

Tissue

Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Urinary Tract 10 | 16,678
Blood and immune system 9 | 16,909
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Male tissues 8 | 17,142
Cardiovascular System 7 | 15,192

Target Family

Enzyme 3 | 4,145
Non-IDG 3 | 12,091
Epigenetic 1 | 242
GPCR 1 | 408
Ion Channel 1 | 344
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sn1-specific diacylglycerol lipase alpha DAGLA Tchem Enzyme -1.11500 11.4 129
Sodium-dependent noradrenaline transporter SLC6A2 Tclin Transporter -2.87529 687.5 105
Coiled-coil domain-containing protein 124 CCDC124 Tdark Non-IDG 0.27 0.87 53
Protein Wnt-5b WNT5B Tbio Non-IDG -1.62833 40.2 161
Lutropin-choriogonadotropic hormone receptor LHCGR Tclin GPCR -2.58909 376.4 243
Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I Tclin Ion Channel -1.95446 85.6 79
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial CYP27B1 Tchem Enzyme -2.70628 492.9 68
Lysine-specific histone demethylase 1A KDM1A Tchem Epigenetic -2.68692 516.3 473
E3 ubiquitin-protein ligase HECTD3 HECTD3 Tdark Enzyme 0.85 0.41 88
Single-stranded DNA-binding protein 2 SSBP2 Tbio Non-IDG -1.01979 11.0 169