Development Level

Tbio 6 | 11,651
Tdark 3 | 6,593
Tclin 1 | 612

Collection

Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

shortened ST segment 10 | 10
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 7 | 11,493
ovarian cancer 5 | 8,520
invasive ductal carcinoma 4 | 2,951
psoriasis 4 | 6,694
acute quadriplegic myopathy 3 | 1,158
breast carcinoma 3 | 1,638
cystic fibrosis 3 | 1,696
glioblastoma 3 | 5,792
lung carcinoma 3 | 2,843
medulloblastoma, large-cell 3 | 6,241
non-small cell lung cancer 3 | 2,890
osteosarcoma 3 | 7,950
pancreatic cancer 3 | 2,398
Breast cancer 2 | 3,578
Kidney cancer 2 | 2,613
adrenocortical carcinoma 2 | 1,428
atypical teratoid / rhabdoid tumor 2 | 5,112
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
nasopharyngeal carcinoma 2 | 1,058
non primary Sjogren syndrome sicca 2 | 891
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Acquired immunodeficiency syndrome 1 | 197
Acquired metabolic disease 1 | 336
Amyotrophic lateral sclerosis 1 | 451
Anhedonia 1 | 27
Anterior segment mesenchymal dysgenesis 1 | 7
Atopic dermatitis 1 | 952
Breast Neoplasms 1 | 445
CATARACT 16, MULTIPLE TYPES 1 | 15
Cancer 1 | 2,499
Carcinoma, Non-Small-Cell Lung 1 | 107
Cardiomegaly 1 | 116
Choreatic disease 1 | 52
Cloudy cornea 1 | 33
Cocaine abuse 1 | 19
Corneal stromal opacities 1 | 33
Depressive disorder 1 | 409
Duchenne muscular dystrophy 1 | 601
Dyskinetic cerebral palsy 1 | 5
Eaton-Lambert syndrome 1 | 40
Endometriosis 1 | 540
Facioscapulohumeral muscular dystrophy 1 | 26
Glaucoma 1 | 239
Griscelli syndrome type 3 1 | 13
Influenza 1 | 142
Liver cancer 1 | 604
MOSAIC VARIEGATED ANEUPLOIDY SYNDROME 1 | 5
Mammary Neoplasms 1 | 425
Melanoma 1 | 711
Microcephaly 1 | 166
Microphthalmia 1 | 76
Multiple Sclerosis 1 | 540
Neoplasm Recurrence, Local 1 | 37
Neoplasms, Germ Cell and Embryonal 1 | 15
Niemann-Pick disease 1 | 14
Parkinson's disease 1 | 392
Patent foramen ovale 1 | 10
Peters anomaly 1 | 16
Pick disease 1 | 1,894
Pontocerebellar hypoplasia 1 | 36
Prostatic Neoplasms 1 | 495
Schizophrenia 1 | 1,160
Skin cancer 1 | 469
Waldenstrons macroglobulinemia 1 | 765
Weight Gain 1 | 100
Wilms Tumor 1 | 28
adrenocortical adenoma 1 | 131
adult high grade glioma 1 | 3,801
astrocytic glioma 1 | 2,597
atypical teratoid/rhabdoid tumor 1 | 357
chronic rhinosinusitis 1 | 512
colon cancer 1 | 1,478
dermatomyositis 1 | 966
diabetes mellitus 1 | 1,728
esophageal adenocarcinoma 1 | 737
group 3 medulloblastoma 1 | 4,104
hereditary spastic paraplegia 1 | 318
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
medulloblastoma 1 | 720
non-inflammatory breast cancer 1 | 66
non-small cell lung carcinoma 1 | 317
oligodendroglioma 1 | 2,850
pediatric high grade glioma 1 | 1,064
primary pancreatic ductal adenocarcinoma 1 | 1,109
sonic hedgehog group medulloblastoma 1 | 467
spina bifida 1 | 1,074
urothelial carcinoma 1 | 318

Tissue

Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 9 | 17,400
Male tissues 9 | 17,142
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678
Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Liver and Pancreas 8 | 16,750
Nervous System 8 | 16,725
Respiratory system 8 | 16,393

Target Family

Non-IDG 6 | 12,091
Enzyme 2 | 4,145
Ion Channel 1 | 344
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DnaJ homolog subfamily C member 5B DNAJC5B Tdark Non-IDG -0.62006 4.33 67
V-set and immunoglobulin domain-containing protein 8 VSIG8 Tdark Non-IDG 0.00000 0
Pituitary homeobox 3 PITX3 Tbio Transcription Factor -2.26232 188.5 134
Sorbin and SH3 domain-containing protein 2 SORBS2 Tbio Non-IDG -1.48653 35.6 82
Protocadherin-18 PCDH18 Tbio Non-IDG -0.69395 5.31 87
GTP-binding protein RAD RRAD Tbio Enzyme -2.52208 334.4 122
Transmembrane protein 256 TMEM256 Tdark Non-IDG 0.15 0.62 15
Pachytene checkpoint protein 2 homolog TRIP13 Tbio Enzyme -1.78655 63.8 217
Potassium voltage-gated channel subfamily G member 2 KCNG2 Tclin Ion Channel -0.41945 2.53 93
RING finger protein 10 RNF10 Tbio Non-IDG -0.83249 6.53 141