Development Level

Tbio 15 | 10,625
Tdark 3 | 7,003
Tchem 1 | 1,890

Collection

Eligible Ion Channel Proteins 1 | 117
Eligible Kinase Proteins 1 | 134

IMPC Term

shortened RR interval 19 | 19
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat/hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

medulloblastoma, large-cell 9 | 6,234
osteosarcoma 9 | 7,933
glioblastoma 8 | 5,572
ovarian cancer 7 | 8,484
atypical teratoid / rhabdoid tumor 5 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
lung adenocarcinoma 5 | 2,713
lung cancer 5 | 4,466
psoriasis 5 | 6,685
Breast cancer 4 | 3,094
Multiple myeloma 4 | 1,327
cystic fibrosis 4 | 1,665
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
malignant mesothelioma 4 | 3,162
non-small cell lung cancer 4 | 2,798
primitive neuroectodermal tumor 4 | 3,031
subependymal giant cell astrocytoma 4 | 2,287
Cancer 3 | 2,346
adrenocortical carcinoma 3 | 1,427
astrocytic glioma 3 | 2,241
colon cancer 3 | 1,475
ependymoma 3 | 2,514
esophageal adenocarcinoma 3 | 737
group 3 medulloblastoma 3 | 2,254
group 4 medulloblastoma 3 | 1,875
hereditary spastic paraplegia 3 | 313
lung carcinoma 3 | 2,844
pancreatic cancer 3 | 2,300
tuberculosis 3 | 1,557
ulcerative colitis 3 | 2,087
Alzheimer's disease 2 | 644
Atopic dermatitis 2 | 944
Liver carcinoma 2 | 217
Microcephaly 2 | 149
Parkinson's disease 2 | 364
Pick disease 2 | 1,893
Pontocerebellar hypoplasia 2 | 29
Rheumatoid Arthritis 2 | 1,160
Stomach Neoplasms 2 | 282
Waldenstrons macroglobulinemia 2 | 765
acute quadriplegic myopathy 2 | 1,157
chronic rhinosinusitis 2 | 512
dermatomyositis 2 | 933
diabetes mellitus 2 | 1,663
ductal carcinoma in situ 2 | 1,745
inflammatory breast cancer 2 | 404
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
invasive ductal carcinoma 2 | 2,950
medulloblastoma 2 | 1,524
non-small cell lung carcinoma 2 | 413
oligodendroglioma 2 | 2,849
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
pediatric high grade glioma 2 | 2,712
pilocytic astrocytoma 2 | 3,086
pituitary cancer 2 | 1,972
sonic hedgehog group medulloblastoma 2 | 1,482
Amyotrophic Lateral Sclerosis 1 | 431
Autistic Disorder 1 | 320
Blindness 1 | 84
Charcot-Marie-Tooth disease 1 | 74
Choreatic disease 1 | 27
Chronic Lymphocytic Leukemia 1 | 242
Colonic Neoplasms 1 | 126
Colorectal Cancer 1 | 47
Colorectal Neoplasms 1 | 217
Disease Progression 1 | 125
Epilepsy 1 | 346
Gaucher disease type 1 1 | 171
Gout 1 | 93
HIV Infections 1 | 100
Heart disease 1 | 279
Heart failure 1 | 80
Hyperplasia 1 | 26
Hypersensitivity reaction type II disease 1 | 235
Influenza 1 | 142
Mammary Neoplasms 1 | 410
Megalocornea 1 | 15
Myopia 1 | 99
Nephrocalcinosis 1 | 18
Neuroblastoma 1 | 78
Neurodegenerative disease 1 | 383
Neuropathy 1 | 210
Ptosis 1 | 42
Renal Cell Carcinoma 1 | 199
Reperfusion Injury 1 | 84
Retinitis pigmentosa 1 | 153
Sideroblastic anemia 1 | 18
Squamous cell carcinoma 1 | 94
Status Epilepticus 1 | 85
Sweat gland carcinoma 1 | 1
Vascular disease 1 | 281
active Crohn's disease 1 | 918
atypical teratoid/rhabdoid tumor 1 | 1,095
breast carcinoma 1 | 1,614
cone-rod dystrophy 1 | 56
nasopharyngeal carcinoma 1 | 1,056
pancreatic carcinoma 1 | 567
progressive supranuclear palsy 1 | 674
tuberculosis and treatment for 3 months 1 | 327
tuberculosis and treatment for 6 months 1 | 686

Tissue

Blood and immune system 19 | 17,995
Cardiovascular System 19 | 17,958
Digestive Tract 19 | 18,473
Endocrine System 19 | 18,512
Female tissues 19 | 18,647
Liver and Pancreas 19 | 18,136
Male tissues 19 | 17,969
Nervous System 19 | 18,561
Skin and soft tissues 19 | 18,115
Urinary Tract 19 | 18,444
Respiratory system 18 | 17,484

Target Family

Non-IDG 9 | 11,971
Enzyme 4 | 4,146
Epigenetic 3 | 242
Ion Channel 1 | 341
Kinase 1 | 634
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Complement component C9 C9 Tbio Non-IDG -1.85517 71.0 229
Protein lin-28 homolog B LIN28B Tbio Transcription Factor -1.99339 100.0 171
Basic leucine zipper and W2 domain-containing protein 2 BZW2 Tbio Non-IDG 0.07 0.41 76
E3 ubiquitin-protein ligase Praja-2 PJA2 Tbio Enzyme -0.52612 2.59 159
5'-AMP-activated protein kinase subunit beta-1 PRKAB1 Tbio Kinase -1.43972 28.8 495
Histone-lysine N-methyltransferase setd3 SETD3 Tdark Epigenetic -0.41218 3.66 84
Heat shock protein beta-1 HSPB1 Tchem Non-IDG -3.05361 939.2 1717
Protein FAM161A FAM161A Tbio Non-IDG -1.36444 25.2 39
Pannexin-3 PANX3 Tbio Ion Channel -1.62005 41.9 62
Vesicle transport through interaction with t-SNAREs homolog 1A VTI1A Tbio Non-IDG -1.11947 13.7 129