Development Level

Tbio 13 | 11,651
Tchem 2 | 1,388
Tdark 2 | 6,593

IMPC Phenotype

shortened RR interval 17 | 17
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 8 | 11,493
glioblastoma 7 | 5,792
medulloblastoma, large-cell 7 | 6,241
ovarian cancer 7 | 8,520
ependymoma 6 | 4,679
malignant mesothelioma 6 | 3,232
group 3 medulloblastoma 5 | 4,104
osteosarcoma 5 | 7,950
Cancer 4 | 2,499
atypical teratoid / rhabdoid tumor 4 | 5,112
cystic fibrosis 4 | 1,696
lung adenocarcinoma 4 | 2,716
lung carcinoma 4 | 2,843
non-small cell lung cancer 4 | 2,890
pancreatic cancer 4 | 2,398
primitive neuroectodermal tumor 4 | 3,035
psoriasis 4 | 6,694
Adenocarcinoma of lung 3 | 142
Breast cancer 3 | 3,578
Multiple myeloma 3 | 1,332
adrenocortical carcinoma 3 | 1,428
astrocytic glioma 3 | 2,597
esophageal adenocarcinoma 3 | 737
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung cancer 3 | 4,740
tuberculosis 3 | 2,010
Atopic dermatitis 2 | 952
Carcinoma, Hepatocellular 2 | 228
Disease Models, Animal 2 | 155
Liver carcinoma 2 | 240
Microcephaly 2 | 166
Retinitis Pigmentosa 2 | 226
Waldenstrons macroglobulinemia 2 | 765
chronic rhinosinusitis 2 | 512
colon cancer 2 | 1,478
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
group 4 medulloblastoma 2 | 1,855
hereditary spastic paraplegia 2 | 318
invasive ductal carcinoma 2 | 2,951
oligodendroglioma 2 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
Acquired immunodeficiency syndrome 1 | 197
Acquired metabolic disease 1 | 336
Adenocarcinoma of lung (disorder) 1 | 60
Adult onset 1 | 82
Age related macular degeneration 1 | 72
Alexander disease 1 | 11
Blindness 1 | 88
Breast Neoplasms 1 | 445
Carcinoma, Non-Small-Cell Lung 1 | 107
Carcinoma, Renal Cell 1 | 124
Carcinoma, Squamous Cell 1 | 110
Cardiomegaly 1 | 116
Cardiomyopathy, Hypertrophic 1 | 24
Cell Transformation, Neoplastic 1 | 97
Charcot-Marie-Tooth disease 1 | 62
Ciliopathy 1 | 71
Congenital pes cavus 1 | 88
Decreased motor NCV 1 | 22
Difficulty walking 1 | 28
Distal amyotrophy 1 | 51
Distal sensory impairment 1 | 52
EMG: neuropathic changes 1 | 15
Entropion 1 | 22
Erythema 1 | 58
Gaucher disease type 3 1 | 67
Griscelli syndrome type 3 1 | 13
HIV Infections 1 | 102
Heart failure 1 | 162
Hypermobility syndrome 1 | 17
Hypertrophic Cardiomyopathy 1 | 117
Immunologic Deficiency Syndromes 1 | 113
Influenza 1 | 142
Kleefstra syndrome 1 | 12
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
MOSAIC VARIEGATED ANEUPLOIDY SYNDROME 1 | 5
Macular degeneration 1 | 65
Mammary Neoplasms 1 | 425
Muscle Cramp 1 | 55
Muscular fasciculation 1 | 22
Myopia 1 | 176
Neoplasms, Germ Cell and Embryonal 1 | 15
Neoplastic Cell Transformation 1 | 89
Peripheral Neuropathy 1 | 134
Ptosis 1 | 48
Renal Cell Carcinoma 1 | 214
Retinitis pigmentosa 28 1 | 19
Slow progression 1 | 89
Squamous cell carcinoma 1 | 129
Wilms Tumor 1 | 28
cone-rod dystrophy 1 | 59
inflammatory breast cancer 1 | 286
non-small cell lung carcinoma 1 | 317

Tissue

Endocrine System 17 | 18,159
Male tissues 17 | 17,142
Skin and soft tissues 17 | 17,230
Digestive Tract 16 | 17,369
Female tissues 16 | 17,400
Urinary Tract 16 | 16,678
Blood and immune system 15 | 16,909
Liver and Pancreas 15 | 16,750
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Cardiovascular System 14 | 15,192

Target Family

Non-IDG 10 | 12,091
Enzyme 4 | 4,145
Epigenetic 1 | 242
Kinase 1 | 634
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Basic leucine zipper and W2 domain-containing protein 2 BZW2 Tbio Non-IDG -0.20261 1.21 83
Complement component C9 C9 Tbio Non-IDG -1.88910 74.6 285
Cyclin-dependent kinase 9 CDK9 Tchem Kinase -3.01545 918.3 372
V-set and immunoglobulin domain-containing protein 8 VSIG8 Tdark Non-IDG 0.00000 0
Histone H1x H1FX Tbio Non-IDG -1.72312 52.8 68
Arrestin-C ARR3 Tbio Non-IDG -1.99324 86.3 161
Protein FAM161A FAM161A Tbio Non-IDG -1.10138 14.2 50
Heat shock protein beta-1 HSPB1 Tchem Non-IDG -2.97780 974.9 1992
Protein lin-28 homolog B LIN28B Tbio Transcription Factor -2.08968 113.4 204
GTP-binding protein RAD RRAD Tbio Enzyme -2.52208 334.4 122