Development Level

Tbio 52 | 10,625
Tdark 17 | 7,003
Tchem 11 | 1,890
Tclin 2 | 602

Collection

GPCR: IDG Consortium (Targets) 1 | 127
Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

short tibia 82 | 82
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat-hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

ovarian cancer 48 | 8,491
glioblastoma 41 | 5,572
psoriasis 41 | 6,685
medulloblastoma, large-cell 40 | 6,234
osteosarcoma 36 | 7,933
atypical teratoid / rhabdoid tumor 34 | 4,369
primitive neuroectodermal tumor 23 | 3,031
pediatric high grade glioma 22 | 2,712
pilocytic astrocytoma 22 | 3,086
Breast cancer 21 | 3,098
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,289
pancreatic cancer 18 | 2,300
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,956
lung cancer 16 | 4,473
oligodendroglioma 16 | 2,849
pituitary cancer 16 | 1,972
invasive ductal carcinoma 15 | 2,950
lung carcinoma 15 | 2,844
Carcinoma 14 | 2,147
malignant mesothelioma 14 | 3,163
primary pancreatic ductal adenocarcinoma 14 | 1,271
Cancer 13 | 2,346
group 3 medulloblastoma 13 | 2,254
subependymal giant cell astrocytoma 13 | 2,287
adult high grade glioma 12 | 2,148
breast carcinoma 12 | 1,614
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,988
ulcerative colitis 12 | 2,087
Pick disease 11 | 1,893
Rheumatoid Arthritis 11 | 1,170
cystic fibrosis 11 | 1,670
ependymoma 11 | 2,514
non-small cell lung cancer 11 | 2,798
posterior fossa group A ependymoma 11 | 1,511
diabetes mellitus 10 | 1,663
group 4 medulloblastoma 10 | 1,875
lung adenocarcinoma 10 | 2,714
medulloblastoma 10 | 1,524
tuberculosis 10 | 1,563
astrocytoma 9 | 1,493
interstitial cystitis 9 | 2,299
juvenile dermatomyositis 9 | 1,189
sonic hedgehog group medulloblastoma 9 | 1,482
Obesity 8 | 616
adrenocortical carcinoma 8 | 1,427
colon cancer 8 | 1,475
cutaneous lupus erythematosus 8 | 1,056
dermatomyositis 8 | 966
non primary Sjogren syndrome sicca 8 | 840
Duchenne muscular dystrophy 7 | 602
Intellectual disability 7 | 573
Parkinson's disease 7 | 364
acute quadriplegic myopathy 7 | 1,157
astrocytic glioma 7 | 2,241
ductal carcinoma in situ 7 | 1,745
Prostatic Neoplasms 6 | 471
aldosterone-producing adenoma 6 | 664
atypical teratoid/rhabdoid tumor 6 | 1,095
esophageal adenocarcinoma 6 | 737
gastric carcinoma 6 | 832
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
posterior fossa group B ependymoma 6 | 1,530
primary Sjogren syndrome 6 | 788
Autistic Disorder 5 | 320
Epilepsy 5 | 346
IGA Glomerulonephritis 5 | 454
active Crohn's disease 5 | 918
acute myeloid leukemia 5 | 785
spina bifida 5 | 1,064
Atopic dermatitis 4 | 944
Multiple Sclerosis 4 | 498
Neurodegenerative disease 4 | 383
Vascular disease 4 | 281
nephrosclerosis 4 | 329
periodontitis 4 | 269
urothelial carcinoma 4 | 318
Amyotrophic Lateral Sclerosis 3 | 432
Coronary artery disease 3 | 240
Endometriosis 3 | 535
Gaucher disease type 1 3 | 171
Gilles de la Tourette syndrome 3 | 47
Juvenile arthritis 3 | 124
Liver disease 3 | 219
Mammary Neoplasms 3 | 410
Osteoporosis 3 | 259
Schizophrenia 3 | 503
active ulcerative colitis 3 | 477
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
chronic lymphosyte leukemia 3 | 232
glioblastoma multiforme 3 | 347
interstitial lung disease 3 | 292
pancreatic carcinoma 3 | 567
pterygium 3 | 74
tuberculosis and treatment for 6 months 3 | 686
Down syndrome 2 | 548
chronic rhinosinusitis 2 | 512
fibroadenoma 2 | 557
hepatocellular carcinoma 2 | 550
mucosa-associated lymphoid tissue lymphoma 2 | 480
nasopharyngeal carcinoma 2 | 1,056

Tissue

Digestive Tract 82 | 18,472
Liver and Pancreas 82 | 18,135
Male tissues 82 | 17,968
Nervous System 82 | 18,560
Blood and immune system 81 | 17,994
Cardiovascular System 81 | 17,957
Endocrine System 81 | 18,511
Female tissues 81 | 18,646
Respiratory system 81 | 17,483
Skin and soft tissues 81 | 18,114
Urinary Tract 81 | 18,443

Target Family

Non-IDG 49 | 11,969
Enzyme 17 | 4,146
Epigenetic 5 | 242
Transcription Factor 3 | 1,400
Transporter 3 | 473
Kinase 2 | 634
GPCR 1 | 408
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
BTB/POZ domain-containing protein 9 BTBD9 Tbio Non-IDG -1.30579 21.1 87
Insulin-like growth factor-binding protein 3 IGFBP3 Tchem Non-IDG -3.34747 2121.3 411
Mediator of RNA polymerase II transcription subunit 25 MED25 Tbio Enzyme -1.76765 56.0 62
Proline dehydrogenase 1, mitochondrial PRODH Tbio Enzyme -2.85387 715.1 193
Mammalian ependymin-related protein 1 EPDR1 Tbio Non-IDG -1.15636 15.5 108
NF-X1-type zinc finger protein NFXL1 NFXL1 Tdark Transcription Factor -0.63682 4.31 14
ADAMTS-like protein 5 ADAMTSL5 Tbio Non-IDG -0.45376 3.09 0
Remodeling and spacing factor 1 RSF1 Tbio Epigenetic -1.65153 49.2 57
RNA-binding protein EWS EWSR1 Tbio Non-IDG -3.01326 1055.2 389
Integral membrane protein 2C ITM2C Tbio Non-IDG -1.60233 33.3 96