Development Level

Tbio 24 | 11,445
Tchem 9 | 1,598
Tclin 3 | 613

IMPC Phenotype

prolonged ST segment 36 | 36
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 21 | 11,493
glioblastoma 15 | 5,792
ovarian cancer 15 | 8,520
psoriasis 14 | 6,694
atypical teratoid / rhabdoid tumor 13 | 5,112
medulloblastoma, large-cell 13 | 6,241
osteosarcoma 13 | 7,950
group 3 medulloblastoma 11 | 4,104
ependymoma 10 | 4,679
adult high grade glioma 9 | 3,801
diabetes mellitus 9 | 1,728
Autosomal recessive predisposition 8 | 1,442
Breast cancer 7 | 3,578
Hypertension 7 | 396
Kidney cancer 7 | 2,613
Schizophrenia 7 | 1,160
lung cancer 7 | 4,740
Cancer 6 | 2,499
Mental Depression 6 | 333
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
primitive neuroectodermal tumor 6 | 3,035
Alcoholic Intoxication, Chronic 5 | 289
Astrocytoma, Pilocytic 5 | 3,081
Depressive disorder 5 | 409
Kidney disease 5 | 430
Obesity 5 | 678
ductal carcinoma in situ 5 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
invasive ductal carcinoma 5 | 2,951
lung adenocarcinoma 5 | 2,716
non-small cell lung cancer 5 | 2,890
oligodendroglioma 5 | 2,850
pituitary cancer 5 | 1,972
Alzheimer's disease 4 | 658
Bipolar Disorder 4 | 666
Coronary artery disease 4 | 268
Diarrhea 4 | 253
Endometriosis 4 | 540
Epilepsy 4 | 792
Hyperglycemia 4 | 137
Hypertensive disease 4 | 292
Multiple myeloma 4 | 1,332
astrocytic glioma 4 | 2,597
breast carcinoma 4 | 1,638
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
pancreatic cancer 4 | 2,398
ulcerative colitis 4 | 1,819
Anemia 3 | 365
Asthma 3 | 385
Atherosclerosis 3 | 291
Atopic dermatitis 3 | 952
Bradycardia 3 | 36
Breast Neoplasms 3 | 445
Carcinoma, Hepatocellular 3 | 228
Cardiovascular system disease 3 | 246
Dementia 3 | 175
Down syndrome 3 | 499
Heart disease 3 | 306
Hypotension 3 | 82
Liver carcinoma 3 | 240
Liver disease 3 | 237
Mammary Neoplasms 3 | 425
Parkinson's disease 3 | 392
Seizures 3 | 596
Substance abuse 3 | 59
adrenocortical carcinoma 3 | 1,428
group 4 medulloblastoma 3 | 1,855
malignant mesothelioma 3 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
tuberculosis 3 | 2,010
Allergic hypersensitivity disease 2 | 126
Cerebrovascular disease 2 | 238
Cholestasis 2 | 155
Dyskinesia, Drug-Induced 2 | 15
Hyperreflexia 2 | 209
Lung Neoplasms 2 | 232
Lung disease 2 | 142
Major Depressive Disorder 2 | 301
Melanoma 2 | 711
Mood Disorders 2 | 184
Movement Disorders 2 | 55
Multiple Sclerosis 2 | 540
Neurodegenerative disease 2 | 414
Peripheral vascular disease 2 | 87
Pick disease 2 | 1,894
Skin cancer 2 | 469
Stomach Neoplasms 2 | 300
Type 2 diabetes mellitus 2 | 272
Unipolar Depression 2 | 250
Urticaria 2 | 67
acute quadriplegic myopathy 2 | 1,158
astrocytoma 2 | 1,146
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 559
hepatocellular carcinoma 2 | 547
pediatric high grade glioma 2 | 1,064
primary pancreatic ductal adenocarcinoma 2 | 1,109
tuberculosis and treatment for 6 months 2 | 409

Tissue

Digestive Tract 35 | 17,369
Liver and Pancreas 35 | 16,750
Nervous System 35 | 16,725
Endocrine System 34 | 18,159
Female tissues 34 | 17,400
Skin and soft tissues 34 | 17,230
Urinary Tract 34 | 16,678
Blood and immune system 32 | 16,909
Male tissues 32 | 17,142
Respiratory system 31 | 16,393
Cardiovascular System 28 | 15,192

Target Family

Non-IDG 21 | 12,091
Enzyme 9 | 4,145
GPCR 2 | 408
Transporter 2 | 473
Ion Channel 1 | 344
Kinase 1 | 634

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
RWD domain-containing protein 3 RWDD3 Tbio Non-IDG -1.02793 10.9 98
Kinesin-like protein KIF2C KIF2C Tbio Non-IDG -2.12404 136.3 256
Septin-5 SEPT5 Tbio Non-IDG -1.71017 49.4 178
Heat-stable enterotoxin receptor GUCY2C Tclin Kinase -2.33494 214.5 228
Thymidylate synthase TYMS Tclin Enzyme -2.93426 732.0 733
Receptor-type tyrosine-protein phosphatase mu PTPRM Tchem Enzyme -1.84748 71.7 144
Ubiquitin-conjugating enzyme E2 G1 UBE2G1 Tbio Non-IDG -0.84360 6.17 155
Isoamyl acetate-hydrolyzing esterase 1 homolog IAH1 Tbio Enzyme -0.79588 7.08 72
Ninein NIN Tbio Non-IDG -2.66807 450.0 66
Serine/threonine-protein phosphatase 4 regulatory subunit 1 PPP4R1 Tbio Enzyme -0.68285 5.42 61