Development Level

Tbio 73 | 11,445
Tdark 7 | 6,588
Tchem 6 | 1,598
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

prenatal lethality prior to he... 87 | 87
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 58 | 11,493
ovarian cancer 53 | 8,520
osteosarcoma 46 | 7,950
medulloblastoma, large-cell 29 | 6,241
lung cancer 28 | 4,740
psoriasis 27 | 6,694
group 3 medulloblastoma 26 | 4,104
atypical teratoid / rhabdoid tumor 22 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,955
glioblastoma 20 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 19 | 3,291
oligodendroglioma 18 | 2,850
ependymoma 16 | 4,679
malignant mesothelioma 16 | 3,232
adult high grade glioma 15 | 3,801
lung carcinoma 15 | 2,843
Kidney cancer 14 | 2,613
astrocytic glioma 14 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
non-small cell lung cancer 14 | 2,890
primitive neuroectodermal tumor 14 | 3,035
tuberculosis 14 | 2,010
Autosomal recessive predisposition 13 | 1,442
Breast cancer 13 | 3,578
pancreatic cancer 13 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
ductal carcinoma in situ 12 | 1,745
Astrocytoma, Pilocytic 11 | 3,081
Cancer 11 | 2,499
Intellectual disability 11 | 1,016
Multiple myeloma 11 | 1,332
lung adenocarcinoma 11 | 2,716
Pick disease 10 | 1,894
breast carcinoma 10 | 1,638
invasive ductal carcinoma 10 | 2,951
Epilepsy 9 | 792
Dull intelligence 8 | 645
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
Seizures 8 | 596
acute quadriplegic myopathy 8 | 1,158
cystic fibrosis 8 | 1,696
interstitial cystitis 8 | 2,312
non primary Sjogren syndrome sicca 8 | 891
primary pancreatic ductal adenocarcinoma 8 | 1,109
spina bifida 8 | 1,074
ulcerative colitis 8 | 1,819
pituitary cancer 7 | 1,972
Cognitive delay 6 | 608
Global developmental delay 6 | 608
Mental and motor retardation 6 | 608
Rheumatoid arthritis 6 | 1,191
Schizophrenia 6 | 1,160
acute myeloid leukemia 6 | 783
adrenocortical carcinoma 6 | 1,428
astrocytoma 6 | 1,146
colon cancer 6 | 1,478
dermatomyositis 6 | 966
diabetes mellitus 6 | 1,728
juvenile dermatomyositis 6 | 1,187
subependymal giant cell astrocytoma 6 | 2,287
Cleft Palate 5 | 271
Liver cancer 5 | 604
Short stature 5 | 531
Small head 5 | 374
group 4 medulloblastoma 5 | 1,855
medulloblastoma 5 | 720
pancreatic carcinoma 5 | 562
pediatric high grade glioma 5 | 1,064
Anemia 4 | 365
Concave bridge of nose 4 | 195
Depressed nasal bridge 4 | 195
Depressed nasal root/bridge 4 | 195
Failure to gain weight 4 | 365
Hypoplastic mandible condyle 4 | 275
Infantile onset 4 | 238
Low set ears 4 | 181
Mandibular hypoplasia 4 | 275
Microcephaly 4 | 166
Micrognathism 4 | 275
Pediatric failure to thrive 4 | 365
Uranostaphyloschisis 4 | 167
active Crohn's disease 4 | 922
atypical teratoid/rhabdoid tumor 4 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
esophageal adenocarcinoma 4 | 737
nasopharyngeal carcinoma 4 | 1,058
Alzheimer's disease 3 | 658
Atopic dermatitis 3 | 952
Bilateral fifth finger clinodactyly 3 | 110
Depressive disorder 3 | 409
Duchenne muscular dystrophy 3 | 601
Prostatic Neoplasms 3 | 495
chronic rhinosinusitis 3 | 512
fibroadenoma 3 | 559
gastric carcinoma 3 | 807
hepatocellular carcinoma 3 | 547
sonic hedgehog group medulloblastoma 3 | 467

Tissue

Endocrine System 87 | 18,159
Male tissues 86 | 17,142
Blood and immune system 85 | 16,909
Digestive Tract 85 | 17,369
Female tissues 85 | 17,400
Nervous System 85 | 16,725
Skin and soft tissues 85 | 17,230
Urinary Tract 85 | 16,678
Respiratory system 84 | 16,393
Liver and Pancreas 83 | 16,750
Cardiovascular System 81 | 15,192

Target Family

Non-IDG 50 | 12,091
Enzyme 23 | 4,145
Transcription Factor 7 | 1,400
Epigenetic 3 | 242
Ion Channel 2 | 344
GPCR 1 | 408
Kinase 1 | 634

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Suppressor of tumorigenicity 14 protein ST14 Tchem Non-IDG -2.50215 338.3 309
Cleavage and polyadenylation specificity factor subunit 3 CPSF3 Tbio Non-IDG -1.47182 27.3 190
Pre-mRNA-splicing factor RBM22 RBM22 Tbio Non-IDG -0.84549 7.65 130
Pre-mRNA-splicing factor CWC22 homolog CWC22 Tbio Non-IDG -3.08456 1172.8 103
Origin recognition complex subunit 1 ORC1 Tbio Non-IDG -1.42573 28.0 148
Mitochondrial import inner membrane translocase subunit TIM16 PAM16 Tbio Enzyme -2.36396 227.6 45
Biogenesis of lysosome-related organelles complex 1 subunit 2 BLOC1S2 Tbio Non-IDG -2.89123 759.6 79
Metal regulatory transcription factor 1 MTF1 Tbio Transcription Factor -1.98140 101.0 135
Disheveled-associated activator of morphogenesis 1 DAAM1 Tbio Non-IDG -1.45166 30.8 269
Volume-regulated anion channel subunit LRRC8A LRRC8A Tbio Non-IDG -1.55179 39.4 129