Development Level

Tbio 3 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

premature death 5 | 5
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

ovarian cancer 4 | 8,520
Cancer 3 | 2,499
Carcinoma 3 | 11,493
Intellectual disability 3 | 1,016
Weight Gain 3 | 100
group 3 medulloblastoma 3 | 4,104
psoriasis 3 | 6,694
Alzheimer's disease 2 | 658
Breast cancer 2 | 3,578
Cerebral atrophy 2 | 178
Degenerative brain disorder 2 | 100
Dull intelligence 2 | 645
Epilepsy 2 | 792
Low intelligence 2 | 645
Low set ears 2 | 181
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Neurodegenerative disease 2 | 414
Pick disease 2 | 1,894
Poor school performance 2 | 645
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Seizures 2 | 596
Sloping forehead 2 | 46
Supratentorial atrophy 2 | 94
breast carcinoma 2 | 1,638
invasive ductal carcinoma 2 | 2,951
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
osteosarcoma 2 | 7,950
Abnormal vision 1 | 52
Amnesia 1 | 17
Amyloidosis 1 | 67
Anxiety Disorders 1 | 38
Autosomal recessive congenital ichthyosis 10 1 | 1
Bicornuate uterus 1 | 11
Brain Diseases 1 | 24
Broad ribs 1 | 12
Cerebral Ischemia 1 | 37
Cerebral calcification 1 | 43
Choanal stenosis 1 | 11
Congenital Nonbullous Ichthyosiform Erythroderma 1 | 16
Congenital ichthyosiform erythroderma 1 | 28
Congenital non-bullous ichthyosiform erythroderma 1 | 7
Decreased projection of midface 1 | 105
Dilatation of ureter 1 | 15
Ectropion 1 | 38
Facial hemangioma 1 | 2
Febrile Convulsions 1 | 14
Hepatoblastoma 1 | 19
HyperCalcification of skull base 1 | 5
HyperMineralization of skull base 1 | 5
Hypertrichosis 1 | 46
Hypesthesia 1 | 7
Hypomyelinating leukodystrophy 1 | 9
Hypoplasia of nipple 1 | 16
Hypoplasia of scrotum 1 | 24
Hypoplastic labia minora 1 | 10
Hypoplastic sternum 1 | 5
Hypotrophic midface 1 | 105
ICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE 10 1 | 1
Inclusion body myositis 1 | 13
Intermediate coronary syndrome 1 | 11
Intestinal disease 1 | 14
Learning Disorders 1 | 29
Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 1 | 2
Leukemia, Myelomonocytic, Juvenile 1 | 20
Long clavicle 1 | 7
Long tract signs 1 | 3
Memory Disorders 1 | 40
Methemoglobinemia 1 | 17
Midface retrusion 1 | 105
Muscle Rigidity 1 | 49
Myeloid Leukemia, Chronic 1 | 23
Narrow palate 1 | 20
Neurodegenerative Diseases 1 | 38
Neurofibrillary degeneration (morphologic abnormality) 1 | 9
Neurogenic Inflammation 1 | 12
Opisthotonus 1 | 14
Plaque, Amyloid 1 | 2
Postnatal growth retardation 1 | 57
Progressive mental retardation 1 | 37
Schinzel-Giedion syndrome 1 | 1
Sclerosis of skull base 1 | 5
Shallow orbits 1 | 13
Short distal phalanges 1 | 50
Short first metacarpals 1 | 11
Short sternum 1 | 5
Single transverse palmar crease 1 | 29
Small labia majora 1 | 16
Small midface 1 | 105
Staphyloenterotoxemia 1 | 18
Stenosis of ureter 1 | 2
Teratoma 1 | 8
Thickened cortex of long bones 1 | 4
Tibial bowing 1 | 19
Toxic shock syndrome 1 | 28
Uroureter 1 | 15
Widely patent fontanels and sutures 1 | 12
pseudo-Hurler polydystrophy 1 | 6

Tissue

Blood and immune system 5 | 16,909
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678
Cardiovascular System 4 | 15,192

Target Family

Enzyme 3 | 4,145
Non-IDG 2 | 12,091

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
SET-binding protein SETBP1 Tbio Non-IDG -2.46805 281.6 98
Cathepsin D CTSD Tchem Enzyme -3.47061 2866.8 779
Patatin-like phospholipase domain-containing protein 1 PNPLA1 Tbio Enzyme -1.33674 19.5 102
tRNA (guanine(26)-N(2))-dimethyltransferase TRMT1 Tbio Enzyme -1.61554 40.5 122
Amyloid-beta A4 protein APP Tchem Non-IDG -3.99225 9853.3 2781