Development Level

Tbio 3 | 11,178
Tchem 2 | 1,885
Tclin 1 | 612
Tdark 1 | 6,569

IMPC Phenotype

polydactyly 7 | 7
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 5 | 11,192
atypical teratoid / rhabdoid tumor 3 | 4,971
ependymoma 3 | 4,559
osteosarcoma 3 | 7,766
Breast cancer 2 | 3,469
Cancer 2 | 2,388
Cervical cancer 2 | 24
Hypospadias 2 | 48
Liver Cirrhosis, Experimental 2 | 733
Low compliance bladder 2 | 11
adrenocortical carcinoma 2 | 1,385
breast carcinoma 2 | 1,589
group 3 medulloblastoma 2 | 4,002
interstitial cystitis 2 | 2,237
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,902
ovarian cancer 2 | 8,297
pituitary cancer 2 | 1,915
subependymal giant cell astrocytoma 2 | 2,230
Absence of secondary sex characteristics 1 | 21
Adrenal Hyperplasia, Congenital 1 | 9
Adrenal hyperplasia 1 | 12
Adrenocorticotropic hormone excess 1 | 5
Adrenogenital Syndrome 1 | 6
Ambiguous Genitalia 1 | 21
Amenorrhea 1 | 56
Anodontia 1 | 10
Anovulation 1 | 20
Antley-Bixler syndrome 1 | 16
Aortic root dilatation 1 | 11
Blastomycosis 1 | 12
Chromoblastomycosis 1 | 10
Ciliary Motility Disorders 1 | 38
Coccidioidomycosis 1 | 8
Congenital adrenal hyperplasia 1 | 71
Decreased fertility in females 1 | 18
Decreased male fertility 1 | 7
Decreased plasma renin activity 1 | 9
Decreased size of teeth 1 | 62
Decreased testosterone level 1 | 4
Decreased width of tooth 1 | 59
Delayed Puberty 1 | 94
Disseminated candidiasis 1 | 4
Dysmenorrhea 1 | 21
Elevated follicle stimulating hormone 1 | 13
Elevated luteinizing hormone 1 | 12
Enlarged polycystic ovaries 1 | 10
Familial Mediterranean fever 1 | 13
Familial adenomatous polyposis 1 | 32
Fanconi syndrome 1 | 14
Fluid overload 1 | 2
Fundus dystrophy 1 | 80
Generalized hyperpigmentation 1 | 22
Gynecomastia 1 | 61
Hereditary nonpolyposis colorectal carcinoma 1 | 18
Histoplasmosis 1 | 13
Hyperkalemia 1 | 17
Hypertension, Malignant 1 | 3
Hypodontia 1 | 81
Hypohidrotic ectodermal dysplasia 1 | 14
Hypokalemia 1 | 50
Hypopituitarism 1 | 36
Hypoplasia of vagina 1 | 12
Increased circulating ACTH level 1 | 8
Increased gastric cancer 1 | 21
Infantile uterus 1 | 23
Leiomyosarcoma of uterus 1 | 13
Low serum estradiol levels 1 | 20
Low serum testosterone levels 1 | 4
Low to undetectable plasma cortisol 1 | 11
Male Pseudohermaphroditism 1 | 17
Malignant Hypertension 1 | 3
Malignant tumor of prostate 1 | 26
Microdontia (disorder) 1 | 59
Missing more than six teeth 1 | 22
Mulibrey nanism 1 | 13
Non-alcoholic Fatty Liver Disease 1 | 40
Oligodontia 1 | 24
Oligodontia-Colorectal Cancer Syndrome 1 | 1
Oligomenorrhea 1 | 16
Opitz-GBBB syndrome 1 | 18
Ovarian Cysts 1 | 40
Paracoccidioidomycosis 1 | 12
Penile Diseases 1 | 3
Photosensitive trichothiodystrophy 1 | 30
Pityriasis versicolor 1 | 19
Premature ovarian failure 1 | 63
Primary gonadal insufficiency 1 | 9
Primary hypogonadism 1 | 35
Primary physiologic amenorrhea 1 | 52
Pseudohermaphroditism 1 | 14
Renal Cell Carcinoma 1 | 211
Rudimentary vagina 1 | 12
Seborrheic dermatitis 1 | 31
Small testicle 1 | 69
Sparse axillary hair 1 | 26
Sparse body hair 1 | 31
Sparse pubic hair 1 | 29
Tinea cruris 1 | 12
Transitional cell carcinoma of bladder 1 | 17
Vertebrobasilar insufficiency 1 | 9

Tissue

Blood and immune system 6 | 16,909
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678
Cardiovascular System 4 | 15,192

Target Family

Enzyme 4 | 4,145
Non-IDG 3 | 12,091

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Steroid 17-alpha-hydroxylase/17,20 lyase CYP17A1 Tclin Enzyme -3.09734 1226.2 369
Ras-related protein Rab-34 RAB34 Tbio Enzyme -1.77250 102.9 72
Axin-2 AXIN2 Tchem Non-IDG -2.44870 241.5 237
Ras-related protein Rab-34, isoform NARR RAB34 Tbio Non-IDG -1.77250 102.9 0
Activating signal cointegrator 1 complex subunit 2 ASCC2 Tdark Non-IDG -0.46489 2.71 85
Gamma-butyrobetaine dioxygenase BBOX1 Tchem Enzyme -2.54972 300.7 253
72 kDa inositol polyphosphate 5-phosphatase INPP5E Tbio Enzyme -1.47845 28.1 63