Development Level

Tbio 13 | 10,625
Tdark 8 | 7,003
Tchem 1 | 1,890

IMPC Term

polydactyly 22 | 22
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat/hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

osteosarcoma 10 | 7,933
ovarian cancer 8 | 8,484
atypical teratoid / rhabdoid tumor 6 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,289
adrenocortical carcinoma 5 | 1,427
group 3 medulloblastoma 5 | 2,254
Breast cancer 4 | 3,094
glioblastoma 4 | 5,572
lung cancer 4 | 4,466
medulloblastoma, large-cell 4 | 6,234
non-small cell lung cancer 4 | 2,798
psoriasis 4 | 6,685
acute myeloid leukemia 3 | 780
gastric carcinoma 3 | 832
interstitial cystitis 3 | 2,299
invasive ductal carcinoma 3 | 2,950
lung carcinoma 3 | 2,844
malignant mesothelioma 3 | 3,162
pituitary cancer 3 | 1,972
posterior fossa group B ependymoma 3 | 1,530
spina bifida 3 | 1,064
subependymal giant cell astrocytoma 3 | 2,287
Cervical cancer 2 | 21
Low compliance bladder 2 | 11
adult high grade glioma 2 | 2,148
ductal carcinoma in situ 2 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
pancreatic cancer 2 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
pediatric high grade glioma 2 | 2,712
pilocytic astrocytoma 2 | 3,086
primary pancreatic ductal adenocarcinoma 2 | 1,271
sonic hedgehog group medulloblastoma 2 | 1,482
Acquired immunodeficiency syndrome 1 | 164
Alport syndrome 1 | 21
Amyotrophic Lateral Sclerosis 1 | 431
Arthritis 1 | 248
Autosomal dominant hypohidrotic ectodermal dysplasia syndrome (disorder) 1 | 3
Brachydactyly 1 | 52
Cancer 1 | 2,346
Cerebral palsy 1 | 28
Chronic obstructive pulmonary disease 1 | 146
Cleft Lip 1 | 91
Colorectal Cancer 1 | 47
Colorectal Neoplasms 1 | 217
Congenital heart disease 1 | 63
Corneal disease 1 | 32
Coronary artery disease 1 | 240
Degenerative polyarthritis 1 | 93
Diarrhea 1 | 155
Early myoclonic encephalopathy 1 | 8
Eosinophilic esophagitis 1 | 31
Gaucher disease type 3 1 | 76
Goodpasture syndrome 1 | 6
Hypermobility syndrome 1 | 17
Hypohidrotic ectodermal dysplasia 1 | 13
Keloid 1 | 34
Keratoconus 1 | 47
Kidney disease 1 | 396
Malaria 1 | 140
Measles 1 | 20
Microcephaly 1 | 149
Neoplastic Syndromes, Hereditary 1 | 48
Neurodegenerative disease 1 | 383
Neurofibromatosis 1 | 37
Osteoarthritis 1 | 96
Osteopetrosis 1 | 40
Osteoporosis 1 | 257
Paraganglioma 1 | 12
Paraplegia 1 | 71
Persistent generalized lymphadenopathy 1 | 15
Phaeochromocytoma 1 | 20
Pheochromocytoma 1 | 22
Pick disease 1 | 1,893
Posterior polymorphous corneal dystrophy 1 | 24
Quadriplegia 1 | 14
Seckel syndrome 1 | 34
Sensorineural hearing loss 1 | 107
Stuttering 1 | 18
Von Hippel-Lindau disease 1 | 11
Waldenstrons macroglobulinemia 1 | 765
acute quadriplegic myopathy 1 | 1,157
aldosterone-producing adenoma 1 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 499
breast carcinoma 1 | 1,614
cystic fibrosis 1 | 1,665
dermatomyositis 1 | 933
facioscapulohumeral dystrophy 1 | 286
glioblastoma multiforme 1 | 347
head and neck cancer 1 | 270
hepatocellular carcinoma 1 | 532
hereditary spastic paraplegia 1 | 313
limb girdle muscular dystrophy 2A 1 | 156
lung adenocarcinoma 1 | 2,713
nail-patella syndrome 1 | 16
nasopharyngeal carcinoma 1 | 1,056
progressive supranuclear palsy 1 | 674
pterygium 1 | 74
tuberculosis and treatment for 6 months 1 | 686

Tissue

Digestive Tract 22 | 18,473
Male tissues 22 | 17,969
Respiratory system 22 | 17,484
Blood and immune system 21 | 17,995
Cardiovascular System 21 | 17,958
Endocrine System 21 | 18,512
Female tissues 21 | 18,647
Liver and Pancreas 21 | 18,136
Nervous System 21 | 18,561
Urinary Tract 21 | 18,444
Skin and soft tissues 20 | 18,115

Target Family

Non-IDG 13 | 11,971
Enzyme 7 | 4,146
Kinase 1 | 634
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transmembrane protein 127 TMEM127 Tbio Non-IDG -1.21612 16.9 25
Serine protease inhibitor Kazal-type 14 SPINK14 Tdark Enzyme 0.00000 1
ELMO domain-containing protein 2 ELMOD2 Tbio Non-IDG -0.39155 3.05 81
tRNA (uracil-5-)-methyltransferase homolog A TRMT2A Tdark Enzyme -0.49402 3.34 90
Heat shock factor 2-binding protein HSF2BP Tdark Non-IDG -0.21085 1.44 51
Homeobox and leucine zipper protein Homez HOMEZ Tbio Transcription Factor -0.84510 7.35 98
Ras-related protein Rab-34 RAB34 Tbio Enzyme 96.1 60
AP-4 complex subunit epsilon-1 AP4E1 Tdark Non-IDG -0.63202 4.65 21
TNF receptor-associated factor 6 TRAF6 Tbio Non-IDG -2.63770 438.1 349
Ras-related protein Rab-34, isoform NARR RAB34 Tdark Non-IDG -1.96831 96.1 0