Development Level

Tbio 5 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

pale liver 6 | 6
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 5 | 11,493
ovarian cancer 4 | 8,520
Cancer 2 | 2,499
Liver Cirrhosis, Experimental 2 | 769
medulloblastoma 2 | 720
osteosarcoma 2 | 7,950
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
psoriasis 2 | 6,694
spina bifida 2 | 1,074
Acanthamoeba keratitis 1 | 1
Accessory rib 1 | 10
Acquired scoliosis 1 | 281
Adrenoleukodystrophy 1 | 29
Atopic dermatitis 1 | 952
Autosomal recessive congenital ichthyosis 1 1 | 3
Autosomal recessive congenital ichthyosis 11 1 | 10
Autosomal recessive congenital ichthyosis 7 1 | 1
Basal Cell Nevus Syndrome 1 | 5
Basal cell carcinoma 1 | 54
Basal cell nevi 1 | 23
Big calvaria 1 | 147
Brachydactyly 1 | 156
Broad flat nasal bridge 1 | 236
Calcification of falx cerebri 1 | 6
Carcinoma, Basal Cell 1 | 28
Cardiac fibroma 1 | 3
Cardiac rhabdomyoma 1 | 5
Cerebral calcification 1 | 43
Class III malocclusion 1 | 78
Coarse facial features 1 | 108
Congenital anomaly of neck 1 | 19
Congenital fusion of ribs 1 | 4
Congenital hemivertebra 1 | 25
Curvature of spine 1 | 282
Deformity of neck 1 | 19
Emery-Dreifuss muscular dystrophy 1 | 23
Endometriosis 1 | 540
Factor VIII deficiency 1 | 10
Fragile X syndrome 1 | 34
Frontal bossing 1 | 157
Fused vertebrae 1 | 25
Gastrointestinal Stromal Tumors 1 | 48
Hamartomatous stomach polyps 1 | 3
Highly variable severity 1 | 157
Hypertrophy of lower jaw 1 | 78
Hypohidrosis 1 | 34
Hypotrichosis 1 | 47
Ichthyoses 1 | 41
Ichthyosis 1 | 56
Ichthyosis linearis circumflexa 1 | 2
Ichthyosis with hypotrichosis, autosomal recessive 1 | 1
Ichthyosis, congenital, autosomal recessive 11 1 | 1
Increased head circumference 1 | 147
Increased size of cranium 1 | 147
Increased size of mandible 1 | 78
Increased size of skull 1 | 147
Irregular ossification of hand bones 1 | 3
Keratocystic Odontogenic Tumor 1 | 3
Klippel-Trenaunay syndrome 1 | 13
Kyphoscoliosis deformity of spine 1 | 60
Malformation of the neck 1 | 19
Mandibular hyperplasia 1 | 78
Melanocytic nevus 1 | 43
Milium Cyst 1 | 16
Motor delay 1 | 147
Myocardial Ischemia 1 | 169
Nasal bridge wide 1 | 236
Netherton syndrome 1 | 15
Nevoid basal cell carcinoma syndrome 1 | 16
No development of motor milestones 1 | 147
Noncancerous mole 1 | 28
Orbital cyst 1 | 8
Ovarian Fibromata 1 | 3
Palmar pit 1 | 4
Parietal bossing 1 | 5
Plantar pits 1 | 4
Pulmonary embolism 1 | 55
Sella Turcica, Bridged 1 | 3
Short 4th metacarpal 1 | 7
Short ribs 1 | 30
Short thumb terminal phalanx 1 | 5
Skin atrophy 1 | 16
Skin tag 1 | 14
Sloping shoulders 1 | 21
Spinal fusion 1 | 25
Sprengel deformity 1 | 16
Sternal anomalies 1 | 19
Strabismus 1 | 270
Thickened facial skin with coarse facial features 1 | 108
Thrombophlebitis 1 | 19
Variable expressivity 1 | 157
Varicose veins 1 | 20
Vertebral body fusion 1 | 25
Vertebral wedging 1 | 4
astrocytoma 1 | 1,146
cystic fibrosis 1 | 1,696
hereditary spastic paraplegia 1 | 318
mandibular excess (physical finding) 1 | 78
red-green color blindness 1 | 3

Tissue

Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

Non-IDG 4 | 12,091
Enzyme 2 | 4,145

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Suppressor of tumorigenicity 14 protein ST14 Tchem Non-IDG -2.50215 338.3 309
Mediator of RNA polymerase II transcription subunit 16 MED16 Tbio Enzyme -0.82499 7.04 154
Biogenesis of lysosome-related organelles complex 1 subunit 2 BLOC1S2 Tbio Non-IDG -2.89123 759.6 79
Unconventional myosin-XVIIIa MYO18A Tbio Non-IDG -1.15048 14.2 35
Cytochrome c oxidase subunit 5B, mitochondrial COX5B Tbio Enzyme -1.54736 33.4 253
Suppressor of fused homolog SUFU Tbio Non-IDG -2.33544 208.6 168