Development Level

Tbio 1 | 11,445

IMPC Phenotype

no spontaneous movement 1 | 1
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Abnormality of the cranial nerves 1 | 7
Achondroplasia 1 | 21
Anteverted ears 1 | 2
Autosomal recessive nonsyndromic deafness 63 1 | 10
Autosomal recessive predisposition 1 | 1,442
Breast Neoplasms 1 | 445
Broad flat nasal bridge 1 | 236
Cancer 1 | 2,499
Carcinoma, Hepatocellular 1 | 228
Cleft Lip 1 | 141
Cleft Palate 1 | 271
Congenital aplasia of inner ear 1 | 1
Congenital small ears 1 | 48
Cranial nerve abnormality 1 | 7
Craniofacial Abnormalities 1 | 151
Deafness with labyrinthine aplasia, microtia, and microdontia 1 | 1
Deafness, Congenital, with Inner Ear Agenesis, Microtia, and Microdontia 1 | 1
Decreased size of teeth 1 | 62
Decreased width of tooth 1 | 59
Downward slant of palpebral fissure 1 | 158
Gross motor development delay 1 | 21
Hearing Loss, Sensorineural 1 | 11
Hypochondroplasia 1 | 10
Hypoplastic mandible condyle 1 | 275
LADD syndrome 1 | 9
Liver carcinoma 1 | 240
Long face 1 | 71
Mammary Neoplasms 1 | 425
Mandibular hypoplasia 1 | 275
Microdontia (disorder) 1 | 59
Micrognathism 1 | 275
Microtia, first degree 1 | 3
Nasal bridge wide 1 | 236
Oculootodental Syndrome 1 | 2
Otodental Dysplasia 1 | 2
Otodental syndrome 1 | 1
Peg-shaped teeth 1 | 8
Pointed chin 1 | 33
Pointed teeth 1 | 8
Profound sensorineural hearing impairment 1 | 4
Sensorineural Hearing Loss (disorder) 1 | 284
Sensorineural hearing loss 1 | 106
Skin tag 1 | 14
Stomatognathic Diseases 1 | 2
Thin hypoplastic alae nasi 1 | 51
Tooth agenesis 1 | 44
Type 1 diabetes mellitus 12 1 | 2
Type 1 diabetes mellitus 4 1 | 7
Type 1 diabetes mellitus 5 1 | 4
Type 1 diabetes mellitus 8 1 | 6
Widely spaced teeth 1 | 31
lung cancer 1 | 4,740
type 1 diabetes mellitus 2 1 | 3

Target Family

Non-IDG 1 | 12,091

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Fibroblast growth factor 3 FGF3 Tbio Non-IDG -2.29270 192.7 118