Development Level

Tbio 17 | 11,445
Tchem 5 | 1,598
Tdark 3 | 6,588
Tclin 1 | 613

IMPC Phenotype

microphthalmia 26 | 26
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 17 | 11,493
osteosarcoma 16 | 7,950
ovarian cancer 16 | 8,520
glioblastoma 12 | 5,792
psoriasis 12 | 6,694
ependymoma 10 | 4,679
medulloblastoma, large-cell 10 | 6,241
Breast cancer 9 | 3,578
atypical teratoid / rhabdoid tumor 9 | 5,112
breast carcinoma 8 | 1,638
group 3 medulloblastoma 8 | 4,104
invasive ductal carcinoma 8 | 2,951
lung cancer 7 | 4,740
non-small cell lung cancer 7 | 2,890
acute myeloid leukemia 6 | 783
adult high grade glioma 6 | 3,801
malignant mesothelioma 6 | 3,232
oligodendroglioma 6 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
primitive neuroectodermal tumor 6 | 3,035
Kidney cancer 5 | 2,613
astrocytoma 5 | 1,146
ductal carcinoma in situ 5 | 1,745
interstitial cystitis 5 | 2,312
lung adenocarcinoma 5 | 2,716
subependymal giant cell astrocytoma 5 | 2,287
Autistic Disorder 4 | 364
Cancer 4 | 2,499
Cognitive delay 4 | 608
Global developmental delay 4 | 608
Intellectual disability 4 | 1,016
Mental and motor retardation 4 | 608
astrocytic glioma 4 | 2,597
chronic rhinosinusitis 4 | 512
pancreatic cancer 4 | 2,398
Astrocytoma, Pilocytic 3 | 3,081
Autosomal recessive predisposition 3 | 1,442
Bipolar Disorder 3 | 666
Dull intelligence 3 | 645
Epilepsy 3 | 792
Infantile onset 3 | 238
Low intelligence 3 | 645
Melanoma 3 | 711
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Muscle hypotonia 3 | 571
Poor school performance 3 | 645
Seizures 3 | 596
adrenocortical carcinoma 3 | 1,428
dermatomyositis 3 | 966
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung carcinoma 3 | 2,843
pituitary cancer 3 | 1,972
posterior fossa group A ependymoma 3 | 468
ulcerative colitis 3 | 1,819
Alcoholic Intoxication, Chronic 2 | 289
Amyotrophic lateral sclerosis 2 | 451
Atopic dermatitis 2 | 952
Atrophy of cerebellum 2 | 103
Carcinoma, Hepatocellular 2 | 228
Cerebellar degeneration 2 | 103
Cerebral atrophy 2 | 178
Cleft Palate 2 | 271
Degenerative brain disorder 2 | 100
Familial aplasia of the vermis 2 | 19
Infratentorial atrophy 2 | 103
Liver carcinoma 2 | 240
Low set ears 2 | 181
Microcephaly 2 | 166
Multiple myeloma 2 | 1,332
Nystagmus 2 | 317
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Skin cancer 2 | 469
Slow progression 2 | 89
Small head 2 | 374
Stomach Neoplasms 2 | 300
Supratentorial atrophy 2 | 94
Waldenstrons macroglobulinemia 2 | 765
aldosterone-producing adenoma 2 | 665
colon cancer 2 | 1,478
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 559
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
juvenile dermatomyositis 2 | 1,187
nasopharyngeal carcinoma 2 | 1,058
spina bifida 2 | 1,074
tuberculosis and treatment for 6 months 2 | 409
Brain Neoplasms 1 | 33
Brucellosis 1 | 24
CNS hypomyelination 1 | 17
Exanthem 1 | 37
Familial Mediterranean fever 1 | 13
Hormone receptor positive malignant neoplasm of breast 1 | 10
Hypomyelination 1 | 17
Muckle-Wells syndrome 1 | 12
Pharyngitis 1 | 17
Pyoderma gangrenosum 1 | 9
osteoporosis-pseudoglioma syndrome 1 | 9

Tissue

Digestive Tract 26 | 17,369
Endocrine System 26 | 18,159
Female tissues 26 | 17,400
Liver and Pancreas 26 | 16,750
Male tissues 26 | 17,142
Nervous System 26 | 16,725
Respiratory system 26 | 16,393
Urinary Tract 26 | 16,678
Blood and immune system 25 | 16,909
Skin and soft tissues 25 | 17,230
Cardiovascular System 23 | 15,192

Target Family

Enzyme 8 | 4,145
Non-IDG 8 | 12,091
Kinase 4 | 634
Transcription Factor 3 | 1,400
GPCR 2 | 408
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
PR domain zinc finger protein 4 PRDM4 Tbio TF/Epigenetic -0.87918 7.84 221
Cadherin-10 CDH10 Tbio Non-IDG -0.86821 9.34 155
Metabotropic glutamate receptor 3 GRM3 Tchem GPCR -2.30964 186.9 274
Activin receptor type-2A ACVR2A Tchem Kinase -2.08745 108.0 315
Metal regulatory transcription factor 1 MTF1 Tbio Transcription Factor -1.98140 101.0 135
Protein FAM13B FAM13B Tbio Non-IDG -1.18916 12.0 77
Anaphase-promoting complex subunit 15 ANAPC15 Tdark Enzyme -0.41378 2.22 27
Protein ABHD11 ABHD11 Tbio Enzyme -0.85496 5.74 96
Protein FMC1 homolog FMC1 Tdark Non-IDG -1.25913 17.6 4
Rho GTPase-activating protein 33 ARHGAP33 Tbio Enzyme -0.79198 7.42 114