Development Level

Tbio 5 | 11,445
Tchem 1 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

irregularly shaped pupil 7 | 7
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 4 | 11,493
medulloblastoma, large-cell 4 | 6,241
osteosarcoma 4 | 7,950
ovarian cancer 4 | 8,520
spina bifida 3 | 1,074
Astrocytoma, Pilocytic 2 | 3,081
Breast cancer 2 | 3,578
Congenital heart disease 2 | 93
Craniofacial Abnormalities 2 | 151
Intellectual disability 2 | 1,016
Kleefstra syndrome 2 | 12
atypical teratoid / rhabdoid tumor 2 | 5,112
gastric cancer 2 | 459
group 3 medulloblastoma 2 | 4,104
interstitial cystitis 2 | 2,312
juvenile dermatomyositis 2 | 1,187
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
primitive neuroectodermal tumor 2 | 3,035
psoriasis 2 | 6,694
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 1 | 21
Adenoid Cystic Carcinoma 1 | 99
Aniridia 1 | 25
Anterior segment mesenchymal dysgenesis 1 | 7
Autistic Disorder 1 | 364
Autosomal recessive nonsyndromic deafness 33 1 | 4
Autosomal recessive nonsyndromic deafness 79 1 | 3
Axenfeld anomaly (disorder) 1 | 3
Axenfeld-Rieger syndrome 1 | 14
Bardet-Biedl syndrome 5 1 | 2
Brittle cornea syndrome 1 | 4
Carcinoma, Adenoid Cystic 1 | 99
Chromosome 17 deletion 1 | 2
Clouding of corneal stroma 1 | 50
Cogan-Reese syndrome 1 | 3
Congenital Heart Defects 1 | 58
Congenital anomaly of face 1 | 56
Congenital deafness 1 | 185
Congenital keratoglobus 1 | 14
Corneal Opacity 1 | 53
Corneal abnormalities 1 | 6
Corneal diameter increased 1 | 13
Corneal disease 1 | 31
Cornela disease 1 | 6
Deafness 1 | 198
Decreased projection of maxilla 1 | 66
Decreased projection of midface 1 | 105
Deficiency of upper jaw bones 1 | 66
Dental abnormalities 1 | 60
Distortion of face 1 | 46
Dysmorphic facies 1 | 46
Embryotoxon 1 | 28
Everted lower lip vermilion 1 | 54
Funny looking face 1 | 46
Hearing Loss, Partial 1 | 185
Heart Defects, Congenital 1 | 37
Highly variable severity 1 | 157
Hydrophthalmos 1 | 19
Hypodontia 1 | 81
Hypoplasia of iris 1 | 10
Hypoplasia of the maxilla 1 | 66
Hypotrophic maxilla 1 | 66
Hypotrophic midface 1 | 105
IRIDOGONIODYSGENESIS, TYPE 2 1 | 1
Irido-corneo-trabecular dysgenesis (disorder) 1 | 10
Iridogoniodysgenesis syndrome 1 | 9
Isolated somatotropin deficiency 1 | 30
Koolen de Vries syndrome 1 | 18
Leukemia, Megakaryoblastic, of Down Syndrome 1 | 8
Liver cancer 1 | 604
Maxillary retrognathia 1 | 66
Midface retrusion 1 | 105
Omenn syndrome 1 | 13
Parkinson's disease 1 | 392
Penile hypospadias 1 | 106
Persistent hyperplastic primary vitreous 1 | 20
Peters anomaly 1 | 16
Pigment dispersion syndrome 1 | 11
Pigmentary iris degeneration 1 | 20
Pitt-Hopkins syndrome 1 | 20
Pituitary hypoplasia 1 | 23
Polycoria 1 | 1
Posterior embryotoxon 1 | 28
Protruding lower lip 1 | 54
Retrusion of upper jaw bones 1 | 66
Rieger syndrome 1 | 8
Septooptic dysplasia 1 | 19
Short philtrum 1 | 53
Small midface 1 | 105
Stricture of anus 1 | 13
Thin upper lip vermilion 1 | 67
Tooth Abnormalities 1 | 69
Tooth agenesis 1 | 44
Variable expressivity 1 | 157
Visceral heterotaxy 1 | 14
facial deformity 1 | 46
hearing impairment 1 | 199
medulloblastoma 1 | 720

Tissue

Endocrine System 7 | 18,159
Cardiovascular System 6 | 15,192
Digestive Tract 6 | 17,369
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678
Blood and immune system 5 | 16,909
Nervous System 5 | 16,725
Respiratory system 5 | 16,393

Target Family

Non-IDG 3 | 12,091
Enzyme 2 | 4,145
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Coiled-coil domain-containing protein R3HCC1L R3HCC1L Tbio Non-IDG -1.17689 12.7 71
Inactive ubiquitin carboxyl-terminal hydrolase 50 USP50 Tdark Enzyme -0.39794 3.10 99
Pituitary homeobox 2 PITX2 Tbio Transcription Factor -2.67290 480.0 220
Ephrin-A5 EFNA5 Tbio Non-IDG -2.57120 355.6 202
KAT8 regulatory NSL complex subunit 1 KANSL1 Tbio Non-IDG -1.27149 17.9 36
E3 ubiquitin-protein ligase SMURF2 SMURF2 Tbio Enzyme -1.86833 75.9 222
Histone-lysine N-methyltransferase EHMT1 EHMT1 Tchem Epigenetic -2.34943 219.8 425