Development Level

Tbio 35 | 10,625
Tdark 10 | 7,003
Tchem 6 | 1,890
Tclin 6 | 602

IMPC Term

increased total body fat amoun... 57 | 57
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat/hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

ovarian cancer 30 | 8,484
osteosarcoma 28 | 7,933
glioblastoma 25 | 5,572
Breast cancer 20 | 3,094
psoriasis 20 | 6,685
invasive ductal carcinoma 19 | 2,950
medulloblastoma, large-cell 18 | 6,234
atypical teratoid / rhabdoid tumor 16 | 4,369
lung cancer 16 | 4,466
non-small cell lung cancer 15 | 2,798
pediatric high grade glioma 13 | 2,712
Pick disease 12 | 1,893
lung adenocarcinoma 12 | 2,713
malignant mesothelioma 12 | 3,162
primitive neuroectodermal tumor 11 | 3,031
subependymal giant cell astrocytoma 11 | 2,287
ependymoma 10 | 2,514
group 4 medulloblastoma 10 | 1,875
pilocytic astrocytoma 10 | 3,086
Cancer 9 | 2,346
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
active Crohn's disease 8 | 918
astrocytic glioma 8 | 2,241
ductal carcinoma in situ 8 | 1,745
group 3 medulloblastoma 8 | 2,254
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,289
oligodendroglioma 8 | 2,849
astrocytoma 7 | 1,493
breast carcinoma 7 | 1,614
diabetes mellitus 7 | 1,663
pancreatic cancer 7 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,795
pituitary cancer 7 | 1,972
tuberculosis 7 | 1,557
Carcinoma 6 | 2,147
Obesity 6 | 616
adrenocortical carcinoma 6 | 1,427
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
lung carcinoma 6 | 2,844
ulcerative colitis 6 | 2,087
Atopic dermatitis 5 | 944
Mammary Neoplasms 5 | 410
adult high grade glioma 5 | 2,148
colon cancer 5 | 1,475
cutaneous lupus erythematosus 5 | 1,056
interstitial cystitis 5 | 2,299
non primary Sjogren syndrome sicca 5 | 840
posterior fossa group A ependymoma 5 | 1,511
posterior fossa group B ependymoma 5 | 1,530
Down syndrome 4 | 548
Hypertension 4 | 287
Intellectual disability 4 | 573
Parkinson's disease 4 | 364
Rheumatoid Arthritis 4 | 1,160
cystic fibrosis 4 | 1,665
primary pancreatic ductal adenocarcinoma 4 | 1,271
progressive supranuclear palsy 4 | 674
sonic hedgehog group medulloblastoma 4 | 1,482
Alzheimer's disease 3 | 644
Amenorrhea 3 | 60
Fatty liver disease 3 | 84
Female infertility 3 | 28
Heart disease 3 | 279
Hypogonadism 3 | 70
Infertility 3 | 163
Multiple myeloma 3 | 1,327
Retinitis pigmentosa 3 | 153
Vascular disease 3 | 281
acute myeloid leukemia 3 | 780
acute quadriplegic myopathy 3 | 1,157
atypical teratoid/rhabdoid tumor 3 | 1,095
chronic rhinosinusitis 3 | 512
fibroadenoma 3 | 557
mucosa-associated lymphoid tissue lymphoma 3 | 480
pancreatic carcinoma 3 | 567
spina bifida 3 | 1,064
Acquired metabolic disease 2 | 267
Adenoma 2 | 165
Adverse reaction to drug 2 | 54
Asthma 2 | 349
Colorectal Neoplasms 2 | 217
Hypertensive disease 2 | 193
Hypospadias 2 | 65
Kidney Diseases 2 | 86
Liver carcinoma 2 | 217
Major Depressive Disorder 2 | 106
Metabolic syndrome X 2 | 155
Microcephaly 2 | 149
Prostate cancer 2 | 172
Prostatic Neoplasms 2 | 471
Stomach Neoplasms 2 | 282
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
gastric cancer 2 | 430
gastric carcinoma 2 | 832
juvenile dermatomyositis 2 | 1,189
medulloblastoma 2 | 1,524
nasopharyngeal carcinoma 2 | 1,056
non-small cell lung carcinoma 2 | 413
primary Sjogren syndrome 2 | 789
tuberculosis and treatment for 6 months 2 | 686

Tissue

Digestive Tract 57 | 18,473
Nervous System 57 | 18,561
Urinary Tract 57 | 18,444
Blood and immune system 56 | 17,995
Endocrine System 56 | 18,512
Female tissues 56 | 18,647
Liver and Pancreas 56 | 18,136
Male tissues 56 | 17,969
Cardiovascular System 55 | 17,958
Respiratory system 54 | 17,484
Skin and soft tissues 54 | 18,115

Target Family

Non-IDG 32 | 11,971
Enzyme 13 | 4,146
GPCR 3 | 406
Transcription Factor 3 | 1,400
Kinase 2 | 634
TF/Epigenetic 2 | 38
Epigenetic 1 | 242
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phosphatidylinositol-glycan biosynthesis class F protein PIGF Tbio Non-IDG -1.85741 66.2 47
Fibroblast growth factor 10 FGF10 Tbio Non-IDG -2.51373 345.1 271
Neurocalcin-delta NCALD Tbio Non-IDG -1.29236 20.2 87
ELMO domain-containing protein 2 ELMOD2 Tbio Non-IDG -0.39155 3.05 81
Leptin receptor LEPR Tclin Non-IDG -2.98449 751.7 530
78 kDa glucose-regulated protein HSPA5 Tchem Non-IDG -3.28487 2003.3 918
Atlastin-2 ATL2 Tbio Non-IDG -1.16934 14.0 77
ER membrane protein complex subunit 8 EMC8 Tdark Non-IDG 0.06 0.41 94
Eomesodermin homolog EOMES Tbio Transcription Factor -2.25701 201.9 256
DNA (cytosine-5)-methyltransferase 3A DNMT3A Tclin Epigenetic -2.80919 625.6 631