Development Level

Tbio 81 | 11,445
Tchem 18 | 1,598
Tdark 10 | 6,588
Tclin 3 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

increased startle reflex 112 | 112
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 82 | 11,493
ovarian cancer 68 | 8,520
osteosarcoma 57 | 7,950
psoriasis 49 | 6,694
medulloblastoma, large-cell 48 | 6,241
lung cancer 44 | 4,740
glioblastoma 43 | 5,792
atypical teratoid / rhabdoid tumor 42 | 5,112
ependymoma 39 | 4,679
group 3 medulloblastoma 38 | 4,104
malignant mesothelioma 33 | 3,232
adult high grade glioma 29 | 3,801
Cancer 27 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,291
Kidney cancer 26 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,989
Breast cancer 24 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,955
primitive neuroectodermal tumor 24 | 3,035
Astrocytoma, Pilocytic 23 | 3,081
oligodendroglioma 21 | 2,850
astrocytic glioma 20 | 2,597
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,962
pancreatic cancer 19 | 2,398
pituitary cancer 19 | 1,972
invasive ductal carcinoma 17 | 2,951
interstitial cystitis 16 | 2,312
Pick disease 15 | 1,894
group 4 medulloblastoma 15 | 1,855
lung adenocarcinoma 15 | 2,716
non-small cell lung cancer 15 | 2,890
Schizophrenia 14 | 1,160
colon cancer 14 | 1,478
diabetes mellitus 13 | 1,728
lung carcinoma 13 | 2,843
subependymal giant cell astrocytoma 13 | 2,287
Obesity 12 | 678
acute myeloid leukemia 12 | 783
cystic fibrosis 12 | 1,696
ulcerative colitis 12 | 1,819
Autosomal recessive predisposition 11 | 1,442
Liver cancer 11 | 604
Melanoma 11 | 711
dermatomyositis 11 | 966
pediatric high grade glioma 11 | 1,064
Epilepsy 10 | 792
Intellectual disability 10 | 1,016
ductal carcinoma in situ 10 | 1,745
Multiple myeloma 9 | 1,332
Skin cancer 9 | 469
acute quadriplegic myopathy 9 | 1,158
adrenocortical carcinoma 9 | 1,428
astrocytoma 9 | 1,146
cutaneous lupus erythematosus 9 | 1,057
spina bifida 9 | 1,074
Seizures 8 | 596
juvenile dermatomyositis 8 | 1,187
tuberculosis 8 | 2,010
aldosterone-producing adenoma 7 | 665
gastric carcinoma 7 | 807
non primary Sjogren syndrome sicca 7 | 891
primary pancreatic ductal adenocarcinoma 7 | 1,109
Adenoma 6 | 167
Alzheimer's disease 6 | 658
Cognitive delay 6 | 608
Dull intelligence 6 | 645
Global developmental delay 6 | 608
Kidney disease 6 | 430
Liver carcinoma 6 | 240
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental and motor retardation 6 | 608
Mental deficiency 6 | 645
Polycystic ovary syndrome 6 | 360
Poor school performance 6 | 645
Short stature 6 | 531
esophageal adenocarcinoma 6 | 737
hepatocellular carcinoma 6 | 547
Atopic dermatitis 5 | 952
Bipolar Disorder 5 | 666
Breast Neoplasms 5 | 445
Carcinoma, Hepatocellular 5 | 228
Colorectal Neoplasms 5 | 243
Crohn's disease 5 | 321
Depressive disorder 5 | 409
Duchenne muscular dystrophy 5 | 601
Fibrous dysplasia 5 | 15
Hypoparathyroidism 5 | 41
Mammary Neoplasms 5 | 425
McCune Albright syndrome 5 | 19
Mesothelioma, Malignant 5 | 105
Pseudohypoparathyroidism 5 | 18
Thyroid cancer 5 | 36
Waldenstrons macroglobulinemia 5 | 765
active Crohn's disease 5 | 922
active ulcerative colitis 5 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
breast carcinoma 5 | 1,638
chronic rhinosinusitis 5 | 512
pancreatic carcinoma 5 | 562

Tissue

Endocrine System 107 | 18,159
Skin and soft tissues 107 | 17,230
Digestive Tract 106 | 17,369
Female tissues 106 | 17,400
Blood and immune system 105 | 16,909
Liver and Pancreas 105 | 16,750
Male tissues 105 | 17,142
Nervous System 105 | 16,725
Respiratory system 104 | 16,393
Urinary Tract 104 | 16,678
Cardiovascular System 98 | 15,192

Target Family

Non-IDG 62 | 12,091
Enzyme 22 | 4,145
Ion Channel 7 | 344
Epigenetic 5 | 242
Transcription Factor 5 | 1,400
Kinase 3 | 634
Nuclear Receptor 3 | 48
TF/Epigenetic 2 | 38
Transporter 2 | 473
GPCR 1 | 408

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
F-box only protein 11 FBXO11 Tbio Non-IDG -1.53905 34.1 258
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184
Adherens junction-associated protein 1 AJAP1 Tbio Non-IDG -1.20907 21.2 25
Myotubularin-related protein 3 MTMR3 Tbio Enzyme -1.05980 10.7 33
Protein FAM83G FAM83G Tbio Non-IDG -1.07402 11.5 72
DnaJ homolog subfamily C member 17 DNAJC17 Tdark Non-IDG -0.24678 1.72 125
RNA binding protein fox-1 homolog 3 RBFOX3 Tbio Non-IDG -3.23341 1462.9 208
Lysosomal-associated transmembrane protein 4B LAPTM4B Tbio Non-IDG -1.90763 86.1 91
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 ARAP1 Tbio Non-IDG -0.99923 14.5 99
Phosphofurin acidic cluster sorting protein 2 PACS2 Tbio Non-IDG -1.72291 53.9 72