Development Level

Tbio 15 | 10,625
Tdark 5 | 7,003
Tchem 1 | 1,890

Collection

Eligible Kinase Proteins 1 | 134
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

increased red blood cell distr... 21 | 21
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat/hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

ovarian cancer 16 | 8,484
osteosarcoma 15 | 7,933
medulloblastoma, large-cell 10 | 6,234
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,289
lung cancer 9 | 4,466
psoriasis 9 | 6,685
glioblastoma 8 | 5,572
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,988
Breast cancer 6 | 3,094
astrocytic glioma 6 | 2,241
atypical teratoid / rhabdoid tumor 6 | 4,369
group 4 medulloblastoma 6 | 1,875
oligodendroglioma 6 | 2,849
esophageal adenocarcinoma 5 | 737
interstitial cystitis 5 | 2,299
invasive ductal carcinoma 5 | 2,950
pilocytic astrocytoma 5 | 3,086
posterior fossa group B ependymoma 5 | 1,530
juvenile dermatomyositis 4 | 1,189
malignant mesothelioma 4 | 3,162
non-small cell lung cancer 4 | 2,798
subependymal giant cell astrocytoma 4 | 2,287
Pick disease 3 | 1,893
astrocytoma 3 | 1,493
ductal carcinoma in situ 3 | 1,745
ependymoma 3 | 2,514
lung adenocarcinoma 3 | 2,713
pancreatic cancer 3 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
pediatric high grade glioma 3 | 2,712
primitive neuroectodermal tumor 3 | 3,031
ulcerative colitis 3 | 2,087
Alzheimer's disease 2 | 644
Barrett's esophagus 2 | 183
Carcinoma 2 | 2,147
Down syndrome 2 | 548
Duchenne muscular dystrophy 2 | 602
Multiple myeloma 2 | 1,327
Neurodegenerative disease 2 | 383
Parkinson's disease 2 | 364
Peripheral vascular disease 2 | 90
Rheumatoid Arthritis 2 | 1,160
Type 2 diabetes mellitus 2 | 189
active Crohn's disease 2 | 918
acute myeloid leukemia 2 | 780
acute quadriplegic myopathy 2 | 1,157
adrenocortical carcinoma 2 | 1,427
adult high grade glioma 2 | 2,148
atypical teratoid/rhabdoid tumor 2 | 1,095
breast carcinoma 2 | 1,614
colon cancer 2 | 1,475
cutaneous lupus erythematosus 2 | 1,056
dermatomyositis 2 | 933
gastric carcinoma 2 | 832
group 3 medulloblastoma 2 | 2,254
inflammatory breast cancer 2 | 404
lung carcinoma 2 | 2,844
medulloblastoma 2 | 1,524
non diabetic and post-ischemic heart failure 2 | 200
progressive supranuclear palsy 2 | 674
tuberculosis 2 | 1,557
Acquired metabolic disease 1 | 267
Allergic rhinitis 1 | 91
Amblyopia 1 | 24
Anemia 1 | 252
Atopic dermatitis 1 | 944
Autistic Disorder 1 | 320
Brain infarction 1 | 17
Cerebrovascular disease 1 | 231
Chronic Lymphocytic Leukemia 1 | 242
Corneal dystrophy 1 | 15
Disease Progression 1 | 125
Epilepsy 1 | 346
Fibrosarcoma 1 | 12
Gaucher disease type 1 1 | 171
Giant Cell Glioblastoma 1 | 12
Hemolytic anemia 1 | 66
Hypertensive disease 1 | 193
Inclusion conjunctivitis 1 | 8
Keratitis 1 | 42
MYELODYSPLASTIC SYNDROME 1 | 36
Osteomyelitis 1 | 20
Pellagra 1 | 25
Stomach Neoplasms 1 | 282
Tetralogy of Fallot 1 | 35
Thalassemia 1 | 46
Waldenstrons macroglobulinemia 1 | 765
facioscapulohumeral dystrophy 1 | 286
gliosarcoma 1 | 19
head and neck cancer and chronic obstructive pulmonary disease 1 | 237
hereditary spastic paraplegia 1 | 313
limb girdle muscular dystrophy 2B 1 | 74
nephrosclerosis 1 | 329
non-small cell lung carcinoma 1 | 413
pituitary cancer 1 | 1,972
pterygium 1 | 74
sarcoidosis 1 | 358
tuberculosis and treatment for 6 months 1 | 686
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 21 | 17,995
Cardiovascular System 21 | 17,958
Endocrine System 21 | 18,512
Female tissues 21 | 18,647
Liver and Pancreas 21 | 18,136
Nervous System 21 | 18,561
Urinary Tract 21 | 18,444
Digestive Tract 20 | 18,473
Male tissues 20 | 17,969
Respiratory system 20 | 17,484
Skin and soft tissues 20 | 18,115

Target Family

Non-IDG 11 | 11,971
Enzyme 7 | 4,146
GPCR 1 | 406
Kinase 1 | 634
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cullin-associated NEDD8-dissociated protein 2 CAND2 Tbio Non-IDG -2.57644 368.9 48
Polypeptide N-acetylgalactosaminyltransferase 18 GALNT18 Tdark Enzyme -0.28065 3.03 33
Tryptophan--tRNA ligase, cytoplasmic WARS Tbio Enzyme -2.98787 974.3 154
Adhesion G protein-coupled receptor F5 ADGRF5 Tbio GPCR -0.84160 8.64 151
Actin-related protein 2/3 complex subunit 1B ARPC1B Tbio Non-IDG -1.03224 12.3 119
Phospholipase D3 PLD3 Tbio Enzyme -1.74821 60.0 74
HBS1-like protein HBS1L Tbio Non-IDG -2.49189 316.2 144
Ninjurin-2 NINJ2 Tbio Non-IDG -1.23503 17.4 43
5'-AMP-activated protein kinase subunit beta-1 PRKAB1 Tbio Kinase -1.43972 28.8 495
F-box only protein 7 FBXO7 Tbio Non-IDG -1.99755 105.5 78