Development Level

Tbio 28 | 11,445
Tchem 8 | 1,598
Tdark 8 | 6,588
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

increased neutrophil cell numb... 46 | 46
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 27 | 11,493
osteosarcoma 25 | 7,950
ovarian cancer 24 | 8,520
glioblastoma 21 | 5,792
medulloblastoma, large-cell 21 | 6,241
psoriasis 21 | 6,694
atypical teratoid / rhabdoid tumor 18 | 5,112
Cancer 15 | 2,499
ependymoma 15 | 4,679
lung cancer 15 | 4,740
invasive ductal carcinoma 12 | 2,951
Astrocytoma, Pilocytic 11 | 3,081
astrocytic glioma 11 | 2,597
group 3 medulloblastoma 11 | 4,104
interstitial cystitis 11 | 2,312
lung carcinoma 11 | 2,843
group 4 medulloblastoma 10 | 1,855
non-small cell lung cancer 10 | 2,890
oligodendroglioma 10 | 2,850
pancreatic cancer 10 | 2,398
cutaneous lupus erythematosus 9 | 1,057
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
malignant mesothelioma 9 | 3,232
primary Sjogren syndrome 9 | 735
tuberculosis 9 | 2,010
ulcerative colitis 9 | 1,819
Kidney cancer 8 | 2,613
adult high grade glioma 8 | 3,801
cystic fibrosis 8 | 1,696
Asthma 7 | 385
Breast cancer 7 | 3,578
ductal carcinoma in situ 7 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
pituitary cancer 7 | 1,972
primitive neuroectodermal tumor 7 | 3,035
Rheumatoid arthritis 6 | 1,191
Schizophrenia 6 | 1,160
hepatocellular carcinoma 6 | 547
lung adenocarcinoma 6 | 2,716
pancreatic carcinoma 6 | 562
Atopic dermatitis 5 | 952
Autosomal recessive predisposition 5 | 1,442
Gaucher disease type 1 5 | 180
Inflammatory bowel disease 5 | 151
Multiple myeloma 5 | 1,332
Pick disease 5 | 1,894
breast carcinoma 5 | 1,638
diabetes mellitus 5 | 1,728
fibroadenoma 5 | 559
juvenile dermatomyositis 5 | 1,187
nasopharyngeal carcinoma 5 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
periodontitis 5 | 293
sarcoidosis 5 | 370
subependymal giant cell astrocytoma 5 | 2,287
Autistic Disorder 4 | 364
Hypersensitivity reaction type II disease 4 | 253
Hypertensive disease 4 | 292
Melanoma 4 | 711
Multiple Sclerosis 4 | 540
active Crohn's disease 4 | 922
adrenocortical carcinoma 4 | 1,428
dermatomyositis 4 | 966
esophageal adenocarcinoma 4 | 737
gastric cancer 4 | 459
pediatric high grade glioma 4 | 1,064
progressive supranuclear palsy 4 | 676
Acquired metabolic disease 3 | 336
Allergic hypersensitivity disease 3 | 126
Arthritis 3 | 290
Arthritis, Rheumatoid 3 | 174
Atherosclerosis 3 | 291
Cardiovascular system disease 3 | 246
Chronic Lymphocytic Leukemia 3 | 262
Coronary artery disease 3 | 268
Dermatitis 3 | 157
Diarrhea 3 | 253
HIV Infections 3 | 102
Heart disease 3 | 306
Hypertension 3 | 396
Influenza 3 | 142
Kidney disease 3 | 430
Liver carcinoma 3 | 240
Lung Neoplasms 3 | 232
Muscle hypotonia 3 | 571
Neurodegenerative disease 3 | 414
Neuropathy 3 | 261
Sepsis 3 | 24
Waldenstrons macroglobulinemia 3 | 765
acute myeloid leukemia 3 | 783
acute quadriplegic myopathy 3 | 1,158
chronic rhinosinusitis 3 | 512
colon cancer 3 | 1,478
mucosa-associated lymphoid tissue lymphoma 3 | 484
primary pancreatic ductal adenocarcinoma 3 | 1,109
Lung disease 2 | 142
Malaria 2 | 160
Peritonitis 2 | 43
head and neck cancer 2 | 271

Tissue

Endocrine System 46 | 18,159
Urinary Tract 46 | 16,678
Blood and immune system 45 | 16,909
Digestive Tract 45 | 17,369
Female tissues 45 | 17,400
Male tissues 45 | 17,142
Nervous System 45 | 16,725
Respiratory system 45 | 16,393
Skin and soft tissues 45 | 17,230
Liver and Pancreas 44 | 16,750
Cardiovascular System 42 | 15,192

Target Family

Non-IDG 27 | 12,091
Enzyme 8 | 4,145
Transcription Factor 5 | 1,400
Epigenetic 2 | 242
Kinase 2 | 634
GPCR 1 | 408
Ion Channel 1 | 344

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ER membrane protein complex subunit 10 EMC10 Tbio Non-IDG -1.41680 25.5 60
Poly(ADP-ribose) glycohydrolase PARG Tchem Enzyme -2.32776 229.4 126
Pre-mRNA-splicing factor CWC22 homolog CWC22 Tbio Non-IDG -3.08456 1172.8 103
Cellular retinoic acid-binding protein 1 CRABP1 Tbio Non-IDG -2.48395 306.2 152
Ankyrin repeat domain-containing protein 27 ANKRD27 Tbio Non-IDG -1.12548 14.6 65
ETS domain-containing transcription factor ERF ERF Tbio Transcription Factor -2.42588 268.8 257
F-box only protein 36 FBXO36 Tdark Non-IDG 0.48 0.00000 91
Coiled-coil domain-containing protein 129 CCDC129 Tdark Non-IDG 1.26 0.05 38
Leptin receptor LEPR Tclin Non-IDG -3.01833 782.6 615
Leucine-rich repeat-containing protein 3 LRRC3 Tdark Non-IDG -0.47568 1.75 31