Development Level

Tbio 28 | 11,445
Tchem 9 | 1,598
Tdark 6 | 6,588
Tclin 2 | 613

IMPC Phenotype

increased mean platelet volume 45 | 45
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 35 | 11,493
osteosarcoma 24 | 7,950
ovarian cancer 24 | 8,520
medulloblastoma, large-cell 23 | 6,241
atypical teratoid / rhabdoid tumor 19 | 5,112
glioblastoma 19 | 5,792
ependymoma 15 | 4,679
psoriasis 15 | 6,694
Kidney cancer 13 | 2,613
lung cancer 13 | 4,740
adult high grade glioma 12 | 3,801
group 3 medulloblastoma 11 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
primitive neuroectodermal tumor 11 | 3,035
Astrocytoma, Pilocytic 10 | 3,081
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
Breast cancer 8 | 3,578
oligodendroglioma 8 | 2,850
Autosomal recessive predisposition 7 | 1,442
group 4 medulloblastoma 7 | 1,855
juvenile dermatomyositis 7 | 1,187
astrocytic glioma 6 | 2,597
cystic fibrosis 6 | 1,696
interstitial cystitis 6 | 2,312
lung carcinoma 6 | 2,843
malignant mesothelioma 6 | 3,232
subependymal giant cell astrocytoma 6 | 2,287
Rheumatoid arthritis 5 | 1,191
astrocytoma 5 | 1,146
diabetes mellitus 5 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pediatric high grade glioma 5 | 1,064
Atopic dermatitis 4 | 952
Cancer 4 | 2,499
Pick disease 4 | 1,894
acute quadriplegic myopathy 4 | 1,158
aldosterone-producing adenoma 4 | 665
medulloblastoma 4 | 720
non-small cell lung cancer 4 | 2,890
tuberculosis 4 | 2,010
Asthma 3 | 385
Decreased platelet count 3 | 111
Gaucher disease type 1 3 | 180
Intellectual disability 3 | 1,016
Multiple myeloma 3 | 1,332
Neurodegenerative disease 3 | 414
Parkinson's disease 3 | 392
Peripheral vascular disease 3 | 87
Schizophrenia 3 | 1,160
Thrombocytopenia 3 | 197
acute myeloid leukemia 3 | 783
colon cancer 3 | 1,478
ductal carcinoma in situ 3 | 1,745
lung adenocarcinoma 3 | 2,716
pancreatic cancer 3 | 2,398
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,109
progressive supranuclear palsy 3 | 676
spina bifida 3 | 1,074
ulcerative colitis 3 | 1,819
Anemia 2 | 365
Autistic Disorder 2 | 364
Babinski Reflex 2 | 100
Bipolar Disorder 2 | 666
Bleeding time prolonged 2 | 31
Breast Neoplasms 2 | 445
Cardiovascular system disease 2 | 246
Depressive disorder 2 | 409
Down syndrome 2 | 499
Dull intelligence 2 | 645
Dysarthria 2 | 192
Endometrial cancer 2 | 311
Epistaxis 2 | 43
Failure to gain weight 2 | 365
Glanzmann's thrombasthenia 2 | 23
Hepatomegaly 2 | 285
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Liver cancer 2 | 604
Melanoma 2 | 711
Mood swings 2 | 77
Multiple Sclerosis 2 | 540
Muscle Weakness 2 | 170
Myopathy 2 | 185
Pediatric failure to thrive 2 | 365
Phenotypic variability 2 | 150
Prostatic Neoplasms 2 | 495
Skin cancer 2 | 469
Substance-Related Disorders 2 | 115
Toxic encephalopathy 2 | 141
Type 2 diabetes mellitus 2 | 272
active Crohn's disease 2 | 922
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
dermatomyositis 2 | 966
esophageal adenocarcinoma 2 | 737
invasive ductal carcinoma 2 | 2,951
mucosa-associated lymphoid tissue lymphoma 2 | 484

Tissue

Endocrine System 44 | 18,159
Blood and immune system 43 | 16,909
Digestive Tract 43 | 17,369
Female tissues 43 | 17,400
Male tissues 42 | 17,142
Skin and soft tissues 42 | 17,230
Liver and Pancreas 40 | 16,750
Respiratory system 40 | 16,393
Nervous System 39 | 16,725
Urinary Tract 39 | 16,678
Cardiovascular System 37 | 15,192

Target Family

Non-IDG 22 | 12,091
Enzyme 9 | 4,145
Epigenetic 3 | 242
Ion Channel 3 | 344
Kinase 3 | 634
GPCR 2 | 408
Transporter 2 | 473
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ewing's tumor-associated antigen 1 ETAA1 Tbio Non-IDG -0.76616 7.50 40
Caskin-1 CASKIN1 Tdark Non-IDG -0.63111 5.31 22
Metabotropic glutamate receptor 7 GRM7 Tchem GPCR -2.25415 190.8 304
Protein polybromo-1 PBRM1 Tchem TF/Epigenetic -1.92500 84.6 97
Phospholipase ABHD3 ABHD3 Tbio Enzyme -0.41218 2.23 91
Zinc finger SWIM domain-containing protein 1 ZSWIM1 Tdark Non-IDG 0.30 0.88 66
Ubiquitin carboxyl-terminal hydrolase 15 USP15 Tbio Enzyme -1.64742 41.6 242
Putative sodium-coupled neutral amino acid transporter 10 SLC38A10 Tdark Transporter -0.27712 1.71 25
Neurobeachin-like protein 2 NBEAL2 Tbio Non-IDG -2.41750 251.4 18
H/ACA ribonucleoprotein complex subunit 2 NHP2 Tbio Non-IDG -1.51951 28.7 54