Development Level

Tbio 63 | 11,445
Tchem 13 | 1,598
Tdark 11 | 6,588
Tclin 5 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125
GPCR: IDG Consortium (Complete... 1 | 25
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

increased mean corpuscular vol... 92 | 92
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 60 | 11,493
osteosarcoma 53 | 7,950
ovarian cancer 52 | 8,520
psoriasis 43 | 6,694
medulloblastoma, large-cell 39 | 6,241
glioblastoma 37 | 5,792
atypical teratoid / rhabdoid tumor 32 | 5,112
Breast cancer 30 | 3,578
non-small cell lung cancer 28 | 2,890
ependymoma 27 | 4,679
lung cancer 27 | 4,740
group 3 medulloblastoma 26 | 4,104
lung adenocarcinoma 22 | 2,716
primitive neuroectodermal tumor 21 | 3,035
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,291
malignant mesothelioma 20 | 3,232
invasive ductal carcinoma 19 | 2,951
adult high grade glioma 18 | 3,801
breast carcinoma 18 | 1,638
Cancer 17 | 2,499
Pick disease 16 | 1,894
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
adrenocortical carcinoma 15 | 1,428
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
oligodendroglioma 15 | 2,850
lung carcinoma 14 | 2,843
pancreatic cancer 14 | 2,398
Astrocytoma, Pilocytic 13 | 3,081
ductal carcinoma in situ 13 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
tuberculosis 13 | 2,010
cystic fibrosis 12 | 1,696
subependymal giant cell astrocytoma 12 | 2,287
colon cancer 11 | 1,478
pituitary cancer 11 | 1,972
Kidney cancer 10 | 2,613
Schizophrenia 10 | 1,160
acute quadriplegic myopathy 10 | 1,158
astrocytic glioma 10 | 2,597
diabetes mellitus 10 | 1,728
group 4 medulloblastoma 10 | 1,855
interstitial cystitis 10 | 2,312
ulcerative colitis 10 | 1,819
Atopic dermatitis 9 | 952
Obesity 9 | 678
aldosterone-producing adenoma 9 | 665
astrocytoma 9 | 1,146
cutaneous lupus erythematosus 9 | 1,057
progressive supranuclear palsy 9 | 676
spina bifida 9 | 1,074
Intellectual disability 8 | 1,016
juvenile dermatomyositis 8 | 1,187
pediatric high grade glioma 8 | 1,064
Rheumatoid arthritis 7 | 1,191
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
dermatomyositis 7 | 966
nasopharyngeal carcinoma 7 | 1,058
Alzheimer's disease 6 | 658
Breast Neoplasms 6 | 445
Liver Cirrhosis, Experimental 6 | 769
acute myeloid leukemia 6 | 783
chronic rhinosinusitis 6 | 512
esophageal adenocarcinoma 6 | 737
fibroadenoma 6 | 559
primary pancreatic ductal adenocarcinoma 6 | 1,109
Autosomal recessive predisposition 5 | 1,442
Bipolar Disorder 5 | 666
Endometriosis 5 | 540
Mammary Neoplasms 5 | 425
gastric carcinoma 5 | 807
urothelial carcinoma 5 | 318
Acquired metabolic disease 4 | 336
Amyotrophic lateral sclerosis 4 | 451
Dull intelligence 4 | 645
Epilepsy 4 | 792
Fatty Liver 4 | 70
Gaucher disease type 1 4 | 180
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Multiple Sclerosis 4 | 540
Multiple myeloma 4 | 1,332
Poor school performance 4 | 645
Vascular disease 4 | 319
active ulcerative colitis 4 | 764
gastric cancer 4 | 459
hepatocellular carcinoma 4 | 547
medulloblastoma 4 | 720
mucosa-associated lymphoid tissue lymphoma 4 | 484
non primary Sjogren syndrome sicca 4 | 891
pancreatic carcinoma 4 | 562
primary Sjogren syndrome 4 | 735
Arthritis, Juvenile 3 | 126
Chronic Lymphocytic Leukemia 3 | 262
Juvenile arthritis 3 | 126
Myocardial Ischemia 3 | 169
Prostatic Neoplasms 3 | 495
Waldenstrons macroglobulinemia 3 | 765
active Crohn's disease 3 | 922
periodontitis 3 | 293

Tissue

Digestive Tract 92 | 17,369
Endocrine System 92 | 18,159
Female tissues 91 | 17,400
Liver and Pancreas 91 | 16,750
Male tissues 91 | 17,142
Nervous System 91 | 16,725
Skin and soft tissues 91 | 17,230
Urinary Tract 91 | 16,678
Blood and immune system 90 | 16,909
Cardiovascular System 90 | 15,192
Respiratory system 90 | 16,393

Target Family

Non-IDG 49 | 12,091
Enzyme 21 | 4,145
Transcription Factor 6 | 1,400
Kinase 4 | 634
GPCR 3 | 408
Ion Channel 3 | 344
Transporter 3 | 473
Epigenetic 2 | 242
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
X-box-binding protein 1 XBP1 Tchem Transcription Factor -2.90444 780.2 514
JmjC domain-containing protein 8 JMJD8 Tdark Non-IDG -0.37566 2.60 71
Protein BTG2 BTG2 Tbio Non-IDG -2.10376 142.7 209
Small kinetochore-associated protein KNSTRN Tbio Non-IDG -1.28291 21.4 32
Transmembrane protein 165 TMEM165 Tbio Non-IDG -1.56011 39.2 89
Carboxypeptidase A1 CPA1 Tchem Enzyme -1.95541 84.1 265
Potassium voltage-gated channel subfamily B member 1 KCNB1 Tclin Ion Channel -2.57484 386.0 303
Potassium voltage-gated channel subfamily G member 2 KCNG2 Tclin Ion Channel -0.41945 2.53 93
Protein spinster homolog 2 SPNS2 Tbio Non-IDG -1.42853 26.4 88