Development Level

Tbio 73 | 11,445
Tdark 14 | 6,588
Tchem 7 | 1,598
Tclin 2 | 613

IMPC Phenotype

increased mean corpuscular hem... 96 | 96
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 66 | 11,493
osteosarcoma 47 | 7,950
ovarian cancer 46 | 8,520
medulloblastoma, large-cell 34 | 6,241
psoriasis 33 | 6,694
atypical teratoid / rhabdoid tumor 30 | 5,112
glioblastoma 30 | 5,792
group 3 medulloblastoma 25 | 4,104
lung cancer 25 | 4,740
ependymoma 24 | 4,679
Astrocytoma, Pilocytic 22 | 3,081
adult high grade glioma 21 | 3,801
Breast cancer 20 | 3,578
Cancer 20 | 2,499
lung adenocarcinoma 20 | 2,716
non-small cell lung cancer 19 | 2,890
primitive neuroectodermal tumor 19 | 3,035
Kidney cancer 18 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
malignant mesothelioma 16 | 3,232
Autosomal recessive predisposition 15 | 1,442
Pick disease 15 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
invasive ductal carcinoma 15 | 2,951
lung carcinoma 15 | 2,843
ulcerative colitis 15 | 1,819
adrenocortical carcinoma 14 | 1,428
subependymal giant cell astrocytoma 14 | 2,287
astrocytic glioma 13 | 2,597
interstitial cystitis 12 | 2,312
oligodendroglioma 12 | 2,850
pancreatic cancer 12 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
Intellectual disability 10 | 1,016
breast carcinoma 10 | 1,638
pituitary cancer 10 | 1,972
tuberculosis 10 | 2,010
ductal carcinoma in situ 9 | 1,745
Epilepsy 8 | 792
Schizophrenia 8 | 1,160
diabetes mellitus 8 | 1,728
group 4 medulloblastoma 8 | 1,855
juvenile dermatomyositis 8 | 1,187
Failure to gain weight 7 | 365
Muscle hypotonia 7 | 571
Pediatric failure to thrive 7 | 365
colon cancer 7 | 1,478
cutaneous lupus erythematosus 7 | 1,057
pediatric high grade glioma 7 | 1,064
Anemia 6 | 365
Kidney disease 6 | 430
Rheumatoid arthritis 6 | 1,191
acute myeloid leukemia 6 | 783
astrocytoma 6 | 1,146
dermatomyositis 6 | 966
Atopic dermatitis 5 | 952
Cognitive delay 5 | 608
Dull intelligence 5 | 645
Global developmental delay 5 | 608
Liver Cirrhosis, Experimental 5 | 769
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental and motor retardation 5 | 608
Mental deficiency 5 | 645
Obesity 5 | 678
Poor school performance 5 | 645
Seizures 5 | 596
Sensorineural Hearing Loss (disorder) 5 | 284
active ulcerative colitis 5 | 764
acute quadriplegic myopathy 5 | 1,158
aldosterone-producing adenoma 5 | 665
gastric carcinoma 5 | 807
medulloblastoma 5 | 720
primary Sjogren syndrome 5 | 735
primary pancreatic ductal adenocarcinoma 5 | 1,109
Anteverted nostril 4 | 191
Breast Neoplasms 4 | 445
Colorectal Neoplasms 4 | 243
Duchenne muscular dystrophy 4 | 601
Hyperreflexia 4 | 209
Infantile onset 4 | 238
Kidney Failure 4 | 111
Multiple myeloma 4 | 1,332
Muscle Spasticity 4 | 195
Nystagmus 4 | 317
Small head 4 | 374
Strabismus 4 | 270
Thrombocytopenia 4 | 197
Tremor 4 | 113
Waldenstrons macroglobulinemia 4 | 765
cystic fibrosis 4 | 1,696
head and neck cancer and chronic obstructive pulmonary disease 4 | 239
nasopharyngeal carcinoma 4 | 1,058
pancreatic carcinoma 4 | 562
sonic hedgehog group medulloblastoma 4 | 467
spina bifida 4 | 1,074
tuberculosis and treatment for 6 months 4 | 409
Endometriosis 3 | 540
esophageal adenocarcinoma 3 | 737

Tissue

Digestive Tract 93 | 17,369
Endocrine System 93 | 18,159
Male tissues 92 | 17,142
Blood and immune system 91 | 16,909
Female tissues 91 | 17,400
Liver and Pancreas 91 | 16,750
Nervous System 90 | 16,725
Skin and soft tissues 90 | 17,230
Urinary Tract 89 | 16,678
Respiratory system 88 | 16,393
Cardiovascular System 85 | 15,192

Target Family

Non-IDG 54 | 12,091
Enzyme 23 | 4,145
Transcription Factor 6 | 1,400
Transporter 6 | 473
Epigenetic 3 | 242
Kinase 3 | 634
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
F-box/LRR-repeat protein 2 FBXL2 Tbio Non-IDG -0.89339 8.63 129
3-hydroxybutyrate dehydrogenase type 2 BDH2 Tbio Enzyme -1.15003 15.8 112
GTP-binding protein SAR1b SAR1B Tbio Enzyme -1.91051 79.7 184
Methylmalonic aciduria and homocystinuria type C protein MMACHC Tbio Non-IDG -1.83573 76.5 233
Zinc finger ZZ-type and EF-hand domain-containing protein 1 ZZEF1 Tdark Non-IDG 0.19 0.86 20
Aryl hydrocarbon receptor repressor AHRR Tbio Transcription Factor -1.68768 52.8 77
Lysosomal-associated transmembrane protein 5 LAPTM5 Tbio Non-IDG -1.07401 14.4 71
Bcl-2-binding component 3 BBC3 Tbio Non-IDG -2.02081 88.0 559
Small kinetochore-associated protein KNSTRN Tbio Non-IDG -1.28291 21.4 32
Protein BTG2 BTG2 Tbio Non-IDG -2.10376 142.7 209