Development Level

Tbio 18 | 11,445
Tchem 9 | 1,598
Tdark 4 | 6,588
Tclin 1 | 613

IMPC Phenotype

increased lymphocyte cell numb... 32 | 32
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 22 | 11,493
ovarian cancer 16 | 8,520
medulloblastoma, large-cell 13 | 6,241
osteosarcoma 13 | 7,950
glioblastoma 12 | 5,792
psoriasis 12 | 6,694
ependymoma 11 | 4,679
Cancer 10 | 2,499
atypical teratoid / rhabdoid tumor 9 | 5,112
lung cancer 9 | 4,740
group 4 medulloblastoma 8 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
Autosomal recessive predisposition 7 | 1,442
Breast cancer 7 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
Kidney cancer 6 | 2,613
Pick disease 6 | 1,894
adult high grade glioma 6 | 3,801
group 3 medulloblastoma 6 | 4,104
juvenile dermatomyositis 6 | 1,187
malignant mesothelioma 6 | 3,232
progressive supranuclear palsy 6 | 676
Astrocytoma, Pilocytic 5 | 3,081
Multiple Sclerosis 5 | 540
Rheumatoid arthritis 5 | 1,191
cystic fibrosis 5 | 1,696
dermatomyositis 5 | 966
diabetes mellitus 5 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
lung adenocarcinoma 5 | 2,716
oligodendroglioma 5 | 2,850
tuberculosis 5 | 2,010
Coronary artery disease 4 | 268
Diarrhea 4 | 253
Hypersensitivity reaction type II disease 4 | 253
Multiple myeloma 4 | 1,332
acute quadriplegic myopathy 4 | 1,158
astrocytic glioma 4 | 2,597
invasive ductal carcinoma 4 | 2,951
lung carcinoma 4 | 2,843
Asthma 3 | 385
Bipolar Disorder 3 | 666
Breast Neoplasms 3 | 445
Ecchymosis 3 | 66
Epistaxis 3 | 43
Fever 3 | 138
Generalized osteopenia 3 | 99
Immunologic Deficiency Syndromes 3 | 113
Increased tendency to bruise 3 | 66
Inflammatory bowel disease 3 | 151
Intellectual disability 3 | 1,016
Kidney disease 3 | 430
Lung disease 3 | 142
Mammary Neoplasms 3 | 425
Neurodegenerative disease 3 | 414
Osteopenia 3 | 99
Schizophrenia 3 | 1,160
Thrombocytopenia 3 | 197
active Crohn's disease 3 | 922
acute myeloid leukemia 3 | 783
astrocytoma 3 | 1,146
breast carcinoma 3 | 1,638
nasopharyngeal carcinoma 3 | 1,058
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
pancreatic carcinoma 3 | 562
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primary pancreatic ductal adenocarcinoma 3 | 1,109
subependymal giant cell astrocytoma 3 | 2,287
Alzheimer's disease 2 | 658
Amyotrophic lateral sclerosis 2 | 451
Anemia 2 | 365
Arthritis 2 | 290
Atopic dermatitis 2 | 952
Cerebrovascular disease 2 | 238
Decreased tendon reflex 2 | 122
Delayed bone age 2 | 136
Depressive disorder 2 | 409
Dermatitis 2 | 157
Down syndrome 2 | 499
Epilepsy 2 | 792
Hypertension 2 | 396
Infantile onset 2 | 238
Liver Cirrhosis 2 | 181
Liver cancer 2 | 604
Major Depressive Disorder 2 | 301
Mental Depression 2 | 333
Neuropathy 2 | 261
Parkinson's disease 2 | 392
Polycystic ovary syndrome 2 | 360
Seizures 2 | 596
Unipolar Depression 2 | 250
Variable expressivity 2 | 157
Vascular disease 2 | 319
Vomiting 2 | 116
active ulcerative colitis 2 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
esophageal adenocarcinoma 2 | 737
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972

Tissue

Blood and immune system 31 | 16,909
Endocrine System 31 | 18,159
Digestive Tract 30 | 17,369
Female tissues 30 | 17,400
Liver and Pancreas 30 | 16,750
Respiratory system 30 | 16,393
Skin and soft tissues 30 | 17,230
Urinary Tract 30 | 16,678
Nervous System 29 | 16,725
Cardiovascular System 28 | 15,192
Male tissues 28 | 17,142

Target Family

Non-IDG 20 | 12,091
Enzyme 8 | 4,145
Transcription Factor 2 | 1,400
GPCR 1 | 408
Kinase 1 | 634

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lysosomal-trafficking regulator LYST Tbio Non-IDG -1.96473 92.5 15
Zinc finger SWIM domain-containing protein 1 ZSWIM1 Tdark Non-IDG 0.30 0.88 66
Carboxypeptidase A1 CPA1 Tchem Enzyme -1.95541 84.1 265
Synaptojanin-1 SYNJ1 Tbio Non-IDG -1.76329 62.0 93
BTB/POZ domain-containing protein KCTD15 KCTD15 Tbio Non-IDG -1.04860 11.7 176
TANK-binding kinase 1-binding protein 1 TBKBP1 Tbio Enzyme -0.59007 2.79 127
Ubiquitin-protein ligase E3C UBE3C Tbio Enzyme -1.12526 14.1 101
Basal body-orientation factor 1 BBOF1 Tdark Non-IDG 0.30 0.89 26
Tumor necrosis factor receptor superfamily member 5 CD40 Tchem Non-IDG -3.50040 3120.3 1879
Atlastin-2 ATL2 Tbio Non-IDG -1.20941 15.1 91