Development Level

Tbio 4 | 10,625
Tchem 3 | 1,890
Tdark 2 | 7,003

IMPC Phenotype

increased lymphocyte cell numb... 9 | 9
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat-hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

medulloblastoma, large-cell 4 | 6,234
psoriasis 4 | 6,685
Coronary artery disease 3 | 240
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
osteosarcoma 3 | 7,933
ovarian cancer 3 | 8,491
Cancer 2 | 2,346
Carcinoma 2 | 2,147
Rheumatoid Arthritis 2 | 1,170
Type 1 diabetes mellitus 2 | 104
atypical teratoid / rhabdoid tumor 2 | 4,369
ependymoma 2 | 2,514
glioblastoma 2 | 5,572
lung adenocarcinoma 2 | 2,714
oligodendroglioma 2 | 2,849
posterior fossa group B ependymoma 2 | 1,530
progressive supranuclear palsy 2 | 674
tuberculosis 2 | 1,563
ulcerative colitis 2 | 2,087
Alobar Holoprosencephaly 1 | 14
Anemia 1 | 252
Anogenital venereal wart 1 | 8
Arthritis, Psoriatic 1 | 15
Asthma 1 | 349
Attenuated Ch??diak-Higashi syndrome 1 | 1
BLEEDING DISORDER, PLATELET-TYPE, 11 1 | 1
Balanoposthitis 1 | 3
Bernard-Soulier syndrome 1 | 14
Bleeding diathesis due to glycoprotein VI deficiency 1 | 1
Bleeding disorder, platelet-type 11 1 | 1
Brain Neoplasms 1 | 23
Breast cancer 1 | 3,098
Cerebrovascular disease 1 | 231
Cervical cancer 1 | 23
Cervix uteri carcinoma in situ 1 | 14
Chediak-Higashi syndrome 1 | 24
Choreatic disease 1 | 27
Crohn Disease 1 | 97
DOID:3394 1 | 1
Diarrhea 1 | 155
Endocarditis 1 | 18
Exfoliation syndrome 1 | 8
Familial partial lipodystrophy 1 | 7
Focal epithelial hyperplasia 1 | 4
Gastrointestinal system disease 1 | 50
Glanzmann's thrombasthenia 1 | 21
Hemophagocytic lymphohistiocytosis 1 | 30
Hepatic encephalopathy 1 | 25
Hermansky-Pudlak syndrome 1 | 43
Hypersensitivity reaction type II disease 1 | 235
Inverted follicular keratosis 1 | 3
LEPROSY, EARLY-ONSET, SUSCEPTIBILITY TO 1 | 1
Leprosy 1 | 77
Lobar Holoprosencephaly 1 | 14
Mammary Neoplasms 1 | 410
Multiple Sclerosis 1 | 498
Myocardial Infarction 1 | 126
Neuroacanthocytosis 1 | 5
Neutropenia 1 | 78
Oculocutaneous albinism 1 | 28
PSORIATIC ARTHRITIS, SUSCEPTIBILITY TO (finding) 1 | 2
Papilloma 1 | 27
Peripheral Neuropathy 1 | 303
Pick disease 1 | 1,893
Platelet storage pool deficiency 1 | 21
Psoriatic arthritis 1 | 85
Recurrent infections 1 | 1
SOLITARY MEDIAN MAXILLARY CENTRAL INCISOR 1 | 14
Semilobar Holoprosencephaly 1 | 14
Sepsis 1 | 21
Spinocerebellar ataxia type 17 1 | 7
Thrombocytopenia 1 | 105
Toxic shock syndrome 1 | 28
Von Willebrand's disease 1 | 19
acute myeloid leukemia 1 | 785
acute quadriplegic myopathy 1 | 1,157
adrenocortical carcinoma 1 | 1,427
adult high grade glioma 1 | 2,148
astrocytic glioma 1 | 2,241
chronic rhinosinusitis 1 | 512
dentatorubral-pallidoluysian atrophy 1 | 21
diabetes mellitus 1 | 1,663
group 3 medulloblastoma 1 | 2,254
group 4 medulloblastoma 1 | 1,875
inflammatory breast cancer 1 | 404
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,289
invasive ductal carcinoma 1 | 2,950
juvenile dermatomyositis 1 | 1,189
lung cancer 1 | 4,473
medulloblastoma 1 | 1,524
non-small cell lung cancer 1 | 2,798
pancreatic cancer 1 | 2,300
pancreatic carcinoma 1 | 567
pediatric high grade glioma 1 | 2,712
pilocytic astrocytoma 1 | 3,086
primary pancreatic ductal adenocarcinoma 1 | 1,271
primitive neuroectodermal tumor 1 | 3,031
spina bifida 1 | 1,064
subependymal giant cell astrocytoma 1 | 2,287

Tissue

Blood and immune system 9 | 17,994
Cardiovascular System 9 | 17,957
Digestive Tract 9 | 18,472
Endocrine System 9 | 18,511
Female tissues 9 | 18,646
Liver and Pancreas 9 | 18,135
Male tissues 9 | 17,968
Nervous System 9 | 18,560
Respiratory system 9 | 17,483
Skin and soft tissues 9 | 18,114
Urinary Tract 9 | 18,443

Target Family

Non-IDG 5 | 11,969
Enzyme 3 | 4,146
Kinase 1 | 634

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ubiquitin carboxyl-terminal hydrolase 47 USP47 Tchem Enzyme -0.67298 5.85 100
Protein phosphatase 1J PPM1J Tdark Enzyme 0.01 1.35 49
Lymphotoxin-alpha LTA Tbio Non-IDG -2.86405 612.8 461
Protein farnesyltransferase subunit beta FNTB Tchem Enzyme -0.82810 7.43 172
F-box only protein 36 FBXO36 Tdark Non-IDG 0.00000 63
Lysosomal-trafficking regulator LYST Tbio Non-IDG -1.93985 87.0 8
Delta-like protein 1 DLL1 Tbio Non-IDG -3.08442 1168.8 297
Platelet glycoprotein VI GP6 Tbio Non-IDG -2.71040 549.1 166
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 PFKFB2 Tchem Kinase -1.63862 45.3 281