Development Level

Tbio 34 | 11,445
Tchem 6 | 1,598
Tdark 5 | 6,588
Tclin 1 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

increased hematocrit 46 | 46
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 32 | 11,493
osteosarcoma 22 | 7,950
ovarian cancer 21 | 8,520
atypical teratoid / rhabdoid tumor 20 | 5,112
glioblastoma 20 | 5,792
medulloblastoma, large-cell 20 | 6,241
psoriasis 20 | 6,694
lung cancer 16 | 4,740
Breast cancer 15 | 3,578
adult high grade glioma 14 | 3,801
invasive ductal carcinoma 14 | 2,951
astrocytic glioma 13 | 2,597
ependymoma 13 | 4,679
oligodendroglioma 13 | 2,850
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
group 3 medulloblastoma 11 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
primitive neuroectodermal tumor 11 | 3,035
Astrocytoma, Pilocytic 10 | 3,081
lung adenocarcinoma 10 | 2,716
non-small cell lung cancer 10 | 2,890
cutaneous lupus erythematosus 9 | 1,057
cystic fibrosis 9 | 1,696
malignant mesothelioma 9 | 3,232
Pick disease 8 | 1,894
ductal carcinoma in situ 8 | 1,745
pancreatic cancer 8 | 2,398
ulcerative colitis 8 | 1,819
Atopic dermatitis 7 | 952
Kidney cancer 7 | 2,613
breast carcinoma 7 | 1,638
colon cancer 7 | 1,478
lung carcinoma 7 | 2,843
subependymal giant cell astrocytoma 7 | 2,287
tuberculosis 7 | 2,010
adrenocortical carcinoma 6 | 1,428
group 4 medulloblastoma 6 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
pediatric high grade glioma 6 | 1,064
dermatomyositis 5 | 966
pituitary cancer 5 | 1,972
primary Sjogren syndrome 5 | 735
primary pancreatic ductal adenocarcinoma 5 | 1,109
Bipolar Disorder 4 | 666
Cancer 4 | 2,499
Rheumatoid arthritis 4 | 1,191
acute myeloid leukemia 4 | 783
acute quadriplegic myopathy 4 | 1,158
diabetes mellitus 4 | 1,728
fibroadenoma 4 | 559
interstitial cystitis 4 | 2,312
medulloblastoma 4 | 720
pancreatic carcinoma 4 | 562
Abortion, Spontaneous 3 | 109
Amyotrophic lateral sclerosis 3 | 451
Down syndrome 3 | 499
Endometrial cancer 3 | 311
Melanoma 3 | 711
Obesity 3 | 678
Polycystic ovary syndrome 3 | 360
Spontaneous abortion 3 | 113
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
gastric carcinoma 3 | 807
nasopharyngeal carcinoma 3 | 1,058
Acquired metabolic disease 2 | 336
Aggressive behavior 2 | 75
Aggressive reaction 2 | 75
Alzheimer's disease 2 | 658
Anemia 2 | 365
Arrhythmogenic right ventricular cardiomyopathy 2 | 30
Arthritis, Juvenile 2 | 126
Asthma 2 | 385
Autosomal recessive predisposition 2 | 1,442
Breast Neoplasms 2 | 445
Chronic Lymphocytic Leukemia 2 | 262
Fundus dystrophy 2 | 83
Hepatomegaly 2 | 285
Hyperinsulinism 2 | 133
Hypogonadism 2 | 173
Intellectual disability 2 | 1,016
Juvenile arthritis 2 | 126
Liver cancer 2 | 604
Macular degeneration 2 | 65
Mammary Neoplasms 2 | 425
Multiple myeloma 2 | 1,332
Physical aggression 2 | 76
Schizophrenia 2 | 1,160
Skin cancer 2 | 469
Stomach Neoplasms 2 | 300
Waldenstrons macroglobulinemia 2 | 765
astrocytoma 2 | 1,146
chronic rhinosinusitis 2 | 512
gastric cancer 2 | 459
hereditary spastic paraplegia 2 | 318
juvenile dermatomyositis 2 | 1,187
mucosa-associated lymphoid tissue lymphoma 2 | 484
non diabetic and post-ischemic heart failure 2 | 200
non primary Sjogren syndrome sicca 2 | 891
posterior fossa group B ependymoma 2 | 416

Tissue

Digestive Tract 46 | 17,369
Endocrine System 46 | 18,159
Male tissues 46 | 17,142
Skin and soft tissues 46 | 17,230
Cardiovascular System 44 | 15,192
Liver and Pancreas 44 | 16,750
Blood and immune system 43 | 16,909
Female tissues 43 | 17,400
Respiratory system 43 | 16,393
Urinary Tract 42 | 16,678
Nervous System 41 | 16,725

Target Family

Non-IDG 30 | 12,091
Enzyme 10 | 4,145
Kinase 3 | 634
GPCR 1 | 408
Transcription Factor 1 | 1,400
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sorting nexin-5 SNX5 Tbio Non-IDG -1.23706 20.8 141
Protein FAM83G FAM83G Tbio Non-IDG -1.07402 11.5 72
Double-stranded RNA-specific editase 1 ADARB1 Tbio Enzyme -2.08959 118.0 103
Sarcospan SSPN Tbio Non-IDG -1.64222 48.7 42
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 AGAP1 Tbio Enzyme -0.83079 8.71 94
Cytochrome b561 CYB561 Tbio Non-IDG -1.41422 21.1 62
Protein angel homolog 1 ANGEL1 Tbio Non-IDG -0.17609 1.15 94
Tubulin polymerization-promoting protein TPPP Tbio Non-IDG -1.95532 92.5 179
Microtubule-associated protein RP/EB family member 3 MAPRE3 Tbio Non-IDG -2.16737 137.1 182
Leptin receptor LEPR Tclin Non-IDG -3.01833 782.6 615