Development Level

Tbio 23 | 11,445
Tdark 10 | 6,588
Tchem 6 | 1,598
Tclin 2 | 613

IMPC Phenotype

increased grip strength 41 | 41
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 32 | 11,493
ovarian cancer 20 | 8,520
medulloblastoma, large-cell 18 | 6,241
psoriasis 18 | 6,694
osteosarcoma 17 | 7,950
Breast cancer 14 | 3,578
atypical teratoid / rhabdoid tumor 11 | 5,112
glioblastoma 11 | 5,792
group 3 medulloblastoma 11 | 4,104
lung cancer 11 | 4,740
ependymoma 10 | 4,679
adult high grade glioma 9 | 3,801
primitive neuroectodermal tumor 9 | 3,035
Cancer 8 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
invasive ductal carcinoma 8 | 2,951
malignant mesothelioma 8 | 3,232
non-small cell lung cancer 8 | 2,890
Multiple myeloma 7 | 1,332
Pick disease 7 | 1,894
adrenocortical carcinoma 7 | 1,428
astrocytic glioma 7 | 2,597
lung adenocarcinoma 7 | 2,716
ulcerative colitis 7 | 1,819
diabetes mellitus 6 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
lung carcinoma 6 | 2,843
oligodendroglioma 6 | 2,850
Kidney cancer 5 | 2,613
breast carcinoma 5 | 1,638
ductal carcinoma in situ 5 | 1,745
interstitial cystitis 5 | 2,312
pituitary cancer 5 | 1,972
spina bifida 5 | 1,074
Astrocytoma, Pilocytic 4 | 3,081
Intellectual disability 4 | 1,016
active Crohn's disease 4 | 922
acute quadriplegic myopathy 4 | 1,158
colon cancer 4 | 1,478
pancreatic cancer 4 | 2,398
subependymal giant cell astrocytoma 4 | 2,287
tuberculosis 4 | 2,010
Blepharophimosis 3 | 70
Breast Neoplasms 3 | 445
Diarrhea 3 | 253
Fetal Growth Retardation 3 | 189
Infant, Small for Gestational Age 3 | 176
Intrauterine retardation 3 | 176
Liver cancer 3 | 604
Mammary Neoplasms 3 | 425
Neurodegenerative disease 3 | 414
Primary biliary cirrhosis 3 | 51
Rheumatoid arthritis 3 | 1,191
Waldenstrons macroglobulinemia 3 | 765
cystic fibrosis 3 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
juvenile dermatomyositis 3 | 1,187
nasopharyngeal carcinoma 3 | 1,058
non primary Sjogren syndrome sicca 3 | 891
pancreatic carcinoma 3 | 562
Alopecia 2 | 115
Arthritis, Rheumatoid 2 | 174
Autosomal recessive predisposition 2 | 1,442
Azoospermia 2 | 110
Choreatic disease 2 | 52
Coronary artery disease 2 | 268
Crohn's disease 2 | 321
Epilepsy 2 | 792
Hepatomegaly 2 | 285
Immune system cancer 2 | 140
Major Depressive Disorder 2 | 301
Mood Disorders 2 | 184
Obesity 2 | 678
Seizures 2 | 596
Small head 2 | 374
Unipolar Depression 2 | 250
Vascular disease 2 | 319
acute myeloid leukemia 2 | 783
chronic rhinosinusitis 2 | 512
cutaneous lupus erythematosus 2 | 1,057
dermatomyositis 2 | 966
esophageal adenocarcinoma 2 | 737
mucosa-associated lymphoid tissue lymphoma 2 | 484
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064
Absent carpal bones 1 | 2
Absent finger 1 | 4
Absent metacarpal(s) 1 | 1
Anteriorly placed anus 1 | 7
Carpal bone anomalies 1 | 5
Congenital hypoplasia of radius 1 | 23
Forearm reduction defects 1 | 2
Juvenile zonular cataracts 1 | 1
Madarosis of eyebrow 1 | 13
Mottled pigmentation 1 | 4
Nail abnormality 1 | 22
Patellar hypoplasia 1 | 2
Radial ray hypoplasia 1 | 23
Rib fusion 1 | 16
Thin hypoplastic alae nasi 1 | 51

Tissue

Endocrine System 38 | 18,159
Female tissues 38 | 17,400
Digestive Tract 37 | 17,369
Skin and soft tissues 37 | 17,230
Blood and immune system 36 | 16,909
Male tissues 36 | 17,142
Respiratory system 36 | 16,393
Urinary Tract 36 | 16,678
Nervous System 35 | 16,725
Cardiovascular System 34 | 15,192
Liver and Pancreas 34 | 16,750

Target Family

Non-IDG 27 | 12,091
Enzyme 7 | 4,145
Epigenetic 2 | 242
Transcription Factor 2 | 1,400
Transporter 2 | 473
Kinase 1 | 634

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
X-box-binding protein 1 XBP1 Tchem Transcription Factor -2.90444 780.2 514
ATP-dependent DNA helicase Q4 RECQL4 Tbio Enzyme 0.00000 0
F-box only protein 47 FBXO47 Tdark Non-IDG -0.03476 0.95 58
Chromobox protein homolog 2 CBX2 Tchem Epigenetic -1.37369 24.3 223
Sodium-dependent phosphate transporter 2 SLC20A2 Tbio Transporter -2.29276 197.3 107
Protein FAM161A FAM161A Tbio Non-IDG -1.10138 14.2 50
Nucleoredoxin NXN Tbio Non-IDG -2.54390 345.4 96
Phosphatidylcholine:ceramide cholinephosphotransferase 1 SGMS1 Tchem Enzyme -1.61164 41.6 0
Enhancer of mRNA-decapping protein 4 EDC4 Tbio Non-IDG -2.26552 178.5 97
NF-kappa-B inhibitor-like protein 1 NFKBIL1 Tbio Non-IDG -1.41875 29.3 137