Development Level

Tbio 49 | 10,625
Tdark 14 | 7,003
Tclin 3 | 602
Tchem 2 | 1,890

Collection

Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

increased fasted circulating g... 68 | 68
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat/hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

ovarian cancer 34 | 8,484
glioblastoma 32 | 5,572
osteosarcoma 29 | 7,933
medulloblastoma, large-cell 28 | 6,234
atypical teratoid / rhabdoid tumor 23 | 4,369
lung cancer 18 | 4,466
primitive neuroectodermal tumor 18 | 3,031
psoriasis 18 | 6,685
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,289
Breast cancer 16 | 3,094
pediatric high grade glioma 16 | 2,712
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,988
non-small cell lung cancer 15 | 2,798
lung carcinoma 14 | 2,844
pancreatic cancer 14 | 2,300
invasive ductal carcinoma 13 | 2,950
malignant mesothelioma 13 | 3,162
pilocytic astrocytoma 13 | 3,086
group 3 medulloblastoma 12 | 2,254
lung adenocarcinoma 11 | 2,713
Carcinoma 10 | 2,147
adrenocortical carcinoma 10 | 1,427
astrocytoma 10 | 1,493
interstitial cystitis 10 | 2,299
ulcerative colitis 10 | 2,087
Pick disease 9 | 1,893
astrocytic glioma 9 | 2,241
oligodendroglioma 9 | 2,849
Cancer 8 | 2,346
adult high grade glioma 8 | 2,148
colon cancer 8 | 1,475
posterior fossa group A ependymoma 8 | 1,511
Atopic dermatitis 7 | 944
Multiple myeloma 7 | 1,327
breast carcinoma 7 | 1,614
gastric carcinoma 7 | 832
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,795
primary pancreatic ductal adenocarcinoma 7 | 1,271
dermatomyositis 6 | 933
ductal carcinoma in situ 6 | 1,745
ependymoma 6 | 2,514
juvenile dermatomyositis 6 | 1,189
medulloblastoma 6 | 1,524
pituitary cancer 6 | 1,972
sonic hedgehog group medulloblastoma 6 | 1,482
diabetes mellitus 5 | 1,663
group 4 medulloblastoma 5 | 1,875
inflammatory breast cancer 5 | 404
spina bifida 5 | 1,064
subependymal giant cell astrocytoma 5 | 2,287
Alzheimer's disease 4 | 644
Intellectual disability 4 | 573
Obesity 4 | 616
aldosterone-producing adenoma 4 | 664
fibroadenoma 4 | 557
tuberculosis 4 | 1,557
urothelial carcinoma 4 | 318
Autistic Disorder 3 | 320
Down syndrome 3 | 548
Duchenne muscular dystrophy 3 | 602
Endometriosis 3 | 535
Gaucher disease type 1 3 | 171
Mammary Neoplasms 3 | 410
Prostatic Neoplasms 3 | 471
Vascular disease 3 | 281
active Crohn's disease 3 | 918
active ulcerative colitis 3 | 477
acute myeloid leukemia 3 | 780
acute quadriplegic myopathy 3 | 1,157
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
cutaneous lupus erythematosus 3 | 1,056
gastric cancer 3 | 430
interstitial lung disease 3 | 291
nasopharyngeal carcinoma 3 | 1,056
progressive supranuclear palsy 3 | 674
tuberculosis and treatment for 3 months 3 | 327
Acquired metabolic disease 2 | 267
Allergic rhinitis 2 | 91
Asthma 2 | 349
Bladder Neoplasm 2 | 109
Cardiovascular system disease 2 | 194
Chronic Lymphocytic Leukemia 2 | 242
Colorectal Neoplasms 2 | 217
Dementia 2 | 129
Eye disease 2 | 55
Glaucoma 2 | 134
Liver carcinoma 2 | 217
Microcephaly 2 | 149
Neurodegenerative disease 2 | 383
Parkinson's disease 2 | 364
Prostate cancer 2 | 172
Substance-Related Disorders 2 | 114
Waldenstrons macroglobulinemia 2 | 765
X-linked cerebral adrenoleukodystrophy 2 | 115
cystic fibrosis 2 | 1,665
hepatocellular carcinoma 2 | 532
mucosa-associated lymphoid tissue lymphoma 2 | 480
primary Sjogren syndrome 2 | 789
substance-related disorder 2 | 105

Tissue

Blood and immune system 68 | 17,995
Endocrine System 68 | 18,512
Female tissues 68 | 18,647
Nervous System 68 | 18,561
Urinary Tract 68 | 18,444
Cardiovascular System 67 | 17,958
Digestive Tract 67 | 18,473
Liver and Pancreas 67 | 18,136
Male tissues 66 | 17,969
Respiratory system 66 | 17,484
Skin and soft tissues 66 | 18,115

Target Family

Non-IDG 38 | 11,971
Enzyme 20 | 4,146
Epigenetic 2 | 242
GPCR 2 | 406
Ion Channel 2 | 341
Transcription Factor 2 | 1,400
Kinase 1 | 634
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
PHD finger-like domain-containing protein 5A PHF5A Tbio Epigenetic -1.94489 96.2 127
Cytochrome c oxidase subunit 7C, mitochondrial COX7C Tdark Enzyme -0.99133 9.67 34
Ubiquitin-conjugating enzyme E2 R1 CDC34 Tbio Non-IDG -2.08055 124.6 194
Golgin subfamily A member 3 GOLGA3 Tbio Non-IDG -1.29668 20.3 130
Tetraspanin-18 TSPAN18 Tbio Non-IDG -0.83372 7.78 40
Calcium uniporter protein, mitochondrial MCU Tbio Ion Channel -2.59256 408.9 18
Lysyl oxidase homolog 1 LOXL1 Tbio Enzyme -2.51621 344.5 145
ATP synthase F(0) complex subunit C2, mitochondrial ATP5G2 Tbio Enzyme -1.03087 9.31 110
WD repeat-containing protein 36 WDR36 Tbio Non-IDG -1.67379 47.1 24
ATP-binding cassette sub-family A member 7 ABCA7 Tbio Transporter -2.14140 148.7 123