Development Level

Tbio 41 | 10,625
Tdark 9 | 7,003
Tchem 5 | 1,890
Tclin 1 | 602

Collection

Eligible Kinase Proteins 2 | 134
Eligible non-olfactory GPCR Proteins 2 | 145
Eligible Ion Channel Proteins 1 | 117

IMPC Term

increased exploration in new e... 56 | 56
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat/hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

ovarian cancer 24 | 8,492
osteosarcoma 20 | 7,933
psoriasis 19 | 6,685
lung cancer 18 | 4,473
glioblastoma 17 | 5,572
medulloblastoma, large-cell 13 | 6,234
malignant mesothelioma 12 | 3,163
Breast cancer 11 | 3,099
atypical teratoid / rhabdoid tumor 11 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,289
pilocytic astrocytoma 9 | 3,086
ulcerative colitis 9 | 2,087
cystic fibrosis 8 | 1,670
group 3 medulloblastoma 8 | 2,254
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,988
invasive ductal carcinoma 8 | 2,950
lung adenocarcinoma 8 | 2,714
lung carcinoma 8 | 2,844
non-small cell lung cancer 8 | 2,798
oligodendroglioma 8 | 2,849
pediatric high grade glioma 8 | 2,712
primitive neuroectodermal tumor 8 | 3,031
astrocytic glioma 7 | 2,241
colon cancer 7 | 1,475
interstitial cystitis 7 | 2,299
pituitary cancer 7 | 1,972
Cancer 6 | 2,346
ductal carcinoma in situ 6 | 1,745
ependymoma 6 | 2,514
group 4 medulloblastoma 6 | 1,875
pancreatic cancer 6 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
active Crohn's disease 5 | 918
adult high grade glioma 5 | 2,148
atypical teratoid/rhabdoid tumor 5 | 1,095
breast carcinoma 5 | 1,614
gastric carcinoma 5 | 832
medulloblastoma 5 | 1,524
nasopharyngeal carcinoma 5 | 1,056
posterior fossa group B ependymoma 5 | 1,530
tuberculosis 5 | 1,563
Down syndrome 4 | 548
Multiple myeloma 4 | 1,328
Prostatic Neoplasms 4 | 471
diabetes mellitus 4 | 1,663
juvenile dermatomyositis 4 | 1,189
subependymal giant cell astrocytoma 4 | 2,287
Mammary Neoplasms 3 | 410
Multiple Sclerosis 3 | 498
Pick disease 3 | 1,893
Prostate cancer 3 | 172
Stomach Neoplasms 3 | 282
Waldenstrons macroglobulinemia 3 | 765
acute myeloid leukemia 3 | 785
esophageal adenocarcinoma 3 | 737
fibroadenoma 3 | 557
primary pancreatic ductal adenocarcinoma 3 | 1,271
progressive supranuclear palsy 3 | 674
sonic hedgehog group medulloblastoma 3 | 1,482
Adenoma 2 | 165
Atopic dermatitis 2 | 944
Carcinoma 2 | 2,147
Colorectal Cancer 2 | 62
Colorectal Neoplasms 2 | 217
Kidney cancer 2 | 121
Liver cancer 2 | 31
Liver neoplasms 2 | 109
Male infertility 2 | 170
Precancerous Conditions 2 | 69
Rheumatoid Arthritis 2 | 1,171
Sinusitis 2 | 30
Skin disease 2 | 65
active ulcerative colitis 2 | 477
adrenocortical carcinoma 2 | 1,427
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
cutaneous lupus erythematosus 2 | 1,056
dermatomyositis 2 | 967
hereditary spastic paraplegia 2 | 313
nephrosclerosis 2 | 329
pancreatic carcinoma 2 | 567
posterior fossa group A ependymoma 2 | 1,511
spina bifida 2 | 1,064
tuberculosis and treatment for 6 months 2 | 686
Age related macular degeneration 1 | 84
Candidiasis 1 | 48
Common cold 1 | 63
Common variable immunodeficiency 1 | 98
Congenital heart disease 1 | 63
Dry eye syndrome 1 | 14
Fibromyalgia 1 | 22
Infant length 1 | 11
Irritable bowel syndrome 1 | 59
Lactose intolerance 1 | 7
Leukemia, Myelocytic, Acute 1 | 113
Neoplasm Invasiveness 1 | 127
Nicotine dependence 1 | 53
Skin cancer 1 | 37
Theileriasis 1 | 13
type I diabetes mellitus 1 | 22

Tissue

Cardiovascular System 56 | 17,958
Endocrine System 56 | 18,512
Female tissues 56 | 18,647
Liver and Pancreas 56 | 18,136
Male tissues 56 | 17,969
Nervous System 56 | 18,561
Urinary Tract 56 | 18,444
Digestive Tract 55 | 18,473
Respiratory system 55 | 17,484
Skin and soft tissues 55 | 18,115
Blood and immune system 54 | 17,995

Target Family

Non-IDG 27 | 11,969
Enzyme 17 | 4,146
Transcription Factor 4 | 1,400
GPCR 2 | 408
Kinase 2 | 634
Transporter 2 | 473
Epigenetic 1 | 242
Ion Channel 1 | 341

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Anaphase-promoting complex subunit 13 ANAPC13 Tbio Enzyme -0.70781 4.87 42
TBCC domain-containing protein 1 TBCCD1 Tbio Non-IDG -0.36798 3.22 55
Interleukin-12 receptor subunit beta-1 IL12RB1 Tbio Non-IDG -2.31330 207.1 227
Glycerophosphodiester phosphodiesterase domain-containing protein 5 GDPD5 Tbio Enzyme -1.14819 16.5 89
Cell cycle checkpoint control protein RAD9A RAD9A Tbio Non-IDG -2.13819 136.3 864
ATP-binding cassette sub-family A member 13 ABCA13 Tbio Transporter -1.07417 12.7 0
Echinoderm microtubule-associated protein-like 2 EML2 Tbio Non-IDG -0.54935 3.11 85
FERM domain-containing protein 4B FRMD4B Tdark Non-IDG -0.61101 4.73 31
Prostate stem cell antigen PSCA Tbio Non-IDG -2.37806 257.9 258
Mucin-5AC MUC5AC Tchem Non-IDG -3.19883 932.0 284