Development Level

Tbio 6 | 11,651
Tdark 2 | 6,593

IMPC Phenotype

increased exploration in new e... 8 | 8
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

osteosarcoma 6 | 7,950
medulloblastoma, large-cell 5 | 6,241
Carcinoma 4 | 11,493
atypical teratoid / rhabdoid tumor 4 | 5,112
Schizophrenia 3 | 1,160
adult high grade glioma 3 | 3,801
astrocytic glioma 3 | 2,597
ependymoma 3 | 4,679
group 3 medulloblastoma 3 | 4,104
group 4 medulloblastoma 3 | 1,855
oligodendroglioma 3 | 2,850
Astrocytoma, Pilocytic 2 | 3,081
Breast cancer 2 | 3,577
Cataract 2 | 297
Depressive disorder 2 | 409
Lens Opacities 2 | 231
glioblastoma 2 | 5,792
invasive ductal carcinoma 2 | 2,950
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
ovarian cancer 2 | 8,519
primitive neuroectodermal tumor 2 | 3,035
psoriasis 2 | 6,694
subependymal giant cell astrocytoma 2 | 2,287
Abortion, Spontaneous 1 | 109
Acquired metabolic disease 1 | 336
Alcoholic Intoxication, Chronic 1 | 289
Alzheimer's disease 1 | 658
Anemia 1 | 365
Autosomal dominant nonsyndromic deafness 13 1 | 2
Autosomal dominant nonsyndromic deafness 21 1 | 3
Autosomal dominant nonsyndromic deafness 31 1 | 3
Bipolar Disorder 1 | 666
CATARACT 16, MULTIPLE TYPES 1 | 15
Cancer 1 | 2,499
Charcot-Marie-Tooth disease type 4D 1 | 1
Cloudy cornea 1 | 33
Cocaine abuse 1 | 19
Concave bridge of nose 1 | 195
Corneal stromal opacities 1 | 33
Defective enamel matrix 1 | 35
Dental Enamel Hypoplasia 1 | 43
Depressed nasal bridge 1 | 195
Depressed nasal root/bridge 1 | 195
Down syndrome 1 | 499
Dysplasia of tooth enamel 1 | 35
Endometriosis 1 | 540
Fibromyalgia 1 | 19
Glaucoma 1 | 239
Hepatitis C 1 | 94
Human immunodeficiency virus infectious disease 1 | 138
Hyperphosphatemia 1 | 32
Hyperphosphatemia (disorder) 1 | 17
Hypersensitivity reaction type II disease 1 | 253
Hypocalcemia 1 | 32
Hypomyelinating leukodystrophy 6 1 | 26
Isolated cases 1 | 72
Late tooth eruption 1 | 61
Leber congenital amaurosis 1 | 69
Leukopenia 1 | 72
Liver cancer 1 | 604
Liver disease 1 | 237
Lymphoproliferative syndrome 1 | 58
Major Depressive Disorder 1 | 301
Marijuana Abuse 1 | 31
Mental Depression 1 | 333
Microphthalmia 1 | 76
Mood Disorders 1 | 184
Multiple Sclerosis 1 | 540
Neoplasm Invasiveness 1 | 161
Neoplasm Recurrence, Local 1 | 37
Neurodegenerative disease 1 | 414
Parkinson's disease 1 | 392
Pick disease 1 | 1,894
Pseudohypoaldosteronism 1 | 23
Pseudohypoparathyroidism 1 | 18
Round face 1 | 45
Round, full face 1 | 45
SERUM PHOSPHATE ELEVATED 1 | 14
Skin disease 1 | 66
Spontaneous abortion 1 | 113
Thin dental enamel 1 | 35
Thrombocytopenia 1 | 197
Unipolar Depression 1 | 250
acute quadriplegic myopathy 1 | 1,158
adrenocortical carcinoma 1 | 1,428
breast carcinoma 1 | 1,637
colon cancer 1 | 1,478
fibroadenoma 1 | 559
interstitial lung disease 1 | 298
lung adenocarcinoma 1 | 2,716
pancreatic cancer 1 | 2,398
pancreatic carcinoma 1 | 562
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pituitary cancer 1 | 1,972
posterior fossa group B ependymoma 1 | 416
progressive supranuclear palsy 1 | 676
tuberculosis 1 | 2,010
tuberculosis and treatment for 6 months 1 | 409
type I diabetes mellitus 1 | 22

Tissue

Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Male tissues 8 | 17,142
Skin and soft tissues 8 | 17,230
Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Urinary Tract 7 | 16,678

Target Family

Non-IDG 4 | 12,091
Enzyme 2 | 4,145
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E3 ubiquitin-protein ligase MYLIP MYLIP Tbio Enzyme -2.05580 115.6 135
Rab11 family-interacting protein 4 RAB11FIP4 Tbio Non-IDG -0.68187 5.48 43
Neural cell adhesion molecule 1 NCAM1 Tbio Non-IDG -3.58910 3930.7 1982
Syntaxin-16 STX16 Tbio Non-IDG -1.42149 22.4 116
Pituitary homeobox 3 PITX3 Tbio Transcription Factor -2.26232 188.5 134
Neurabin-2 PPP1R9B Tdark Non-IDG 0.00000 0
Tripartite motif-containing protein 66 TRIM66 Tdark Epigenetic -0.11394 2.15 17
Methionine--tRNA ligase, mitochondrial MARS2 Tbio Enzyme -1.42617 25.3 73