Development Level

Tbio 22 | 11,445
Tdark 3 | 6,588
Tclin 2 | 613
Tchem 1 | 1,598

IMPC Phenotype

increased circulating total pr... 28 | 28
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 17 | 11,493
psoriasis 15 | 6,694
osteosarcoma 13 | 7,950
ovarian cancer 12 | 8,520
glioblastoma 11 | 5,792
ependymoma 10 | 4,679
medulloblastoma, large-cell 10 | 6,241
Cancer 7 | 2,499
lung adenocarcinoma 7 | 2,716
lung cancer 7 | 4,740
primitive neuroectodermal tumor 7 | 3,035
Astrocytoma, Pilocytic 6 | 3,081
astrocytic glioma 6 | 2,597
non-small cell lung cancer 6 | 2,890
atypical teratoid / rhabdoid tumor 5 | 5,112
diabetes mellitus 5 | 1,728
esophageal adenocarcinoma 5 | 737
group 3 medulloblastoma 5 | 4,104
pancreatic cancer 5 | 2,398
Breast cancer 4 | 3,578
Hypertension 4 | 396
adult high grade glioma 4 | 3,801
breast carcinoma 4 | 1,638
lung carcinoma 4 | 2,843
oligodendroglioma 4 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Autosomal recessive predisposition 3 | 1,442
Diarrhea 3 | 253
Hypertensive disease 3 | 292
Kidney cancer 3 | 2,613
Kidney disease 3 | 430
Meniere's disease 3 | 24
Multiple myeloma 3 | 1,332
Obesity 3 | 678
Vascular disease 3 | 319
cystic fibrosis 3 | 1,696
ductal carcinoma in situ 3 | 1,745
gastric carcinoma 3 | 807
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
medulloblastoma 3 | 720
pancreatic carcinoma 3 | 562
pediatric high grade glioma 3 | 1,064
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
ulcerative colitis 3 | 1,819
urothelial carcinoma 3 | 318
Animal Mammary Neoplasms 2 | 136
Atopic dermatitis 2 | 952
Bladder Neoplasm 2 | 112
Brain Edema 2 | 50
Breast Neoplasms 2 | 445
Cardiac Arrhythmia 2 | 103
Choanal Atresia 2 | 42
Cognitive delay 2 | 608
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Downward slant of palpebral fissure 2 | 158
Dull intelligence 2 | 645
Female infertility 2 | 30
Global developmental delay 2 | 608
Hyperglycemia 2 | 137
Hypoglycemia 2 | 152
Hypothyroidism 2 | 122
Infertility 2 | 188
Infertility, Female 2 | 28
Insulin Resistance 2 | 72
Intellectual disability 2 | 1,016
Low intelligence 2 | 645
Major Depressive Disorder 2 | 301
Mammary Neoplasms 2 | 425
Mammary Neoplasms, Animal 2 | 136
Mammary Neoplasms, Experimental 2 | 154
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Oligohydramnios 2 | 52
Pain 2 | 103
Poor school performance 2 | 645
Schizophrenia 2 | 1,160
Short nose 2 | 132
Small nose 2 | 132
Unipolar Depression 2 | 250
Urinary Bladder Neoplasms 2 | 114
acute myeloid leukemia 2 | 783
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
colon cancer 2 | 1,478
cutaneous lupus erythematosus 2 | 1,057
hepatocellular carcinoma 2 | 547
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
malignant mesothelioma 2 | 3,232
pituitary cancer 2 | 1,972
primary Sjogren syndrome 2 | 735
primary pancreatic ductal adenocarcinoma 2 | 1,109

Tissue

Blood and immune system 27 | 16,909
Endocrine System 27 | 18,159
Digestive Tract 25 | 17,369
Female tissues 25 | 17,400
Skin and soft tissues 25 | 17,230
Urinary Tract 25 | 16,678
Liver and Pancreas 24 | 16,750
Male tissues 24 | 17,142
Nervous System 22 | 16,725
Respiratory system 22 | 16,393
Cardiovascular System 21 | 15,192

Target Family

Non-IDG 17 | 12,091
Enzyme 7 | 4,145
Epigenetic 1 | 242
GPCR 1 | 408
Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Aquaporin-1 AQP1 Tbio Non-IDG -3.08125 1107.4 374
Serine protease 27 PRSS27 Tbio Enzyme -2.20602 159.4 151
C-X-C chemokine receptor type 2 CXCR2 Tchem GPCR -2.87313 723.9 643
Calpain-12 CAPN12 Tdark Non-IDG -0.45780 3.51 74
SKI/DACH domain-containing protein 1 SKIDA1 Tdark Non-IDG -0.23045 1.67 0
Leptin receptor LEPR Tclin Non-IDG -3.01833 782.6 615
Estradiol 17-beta-dehydrogenase 11 HSD17B11 Tbio Enzyme -0.99026 11.0 141
Calsequestrin-1 CASQ1 Tbio Non-IDG -1.96476 86.8 103
Extracellular serine/threonine protein kinase FAM20C FAM20C Tbio Enzyme -2.32591 210.3 90
Estrogen receptor beta ESR2 Tclin Nuclear Receptor -3.57388 3765.2 1096