Development Level

Tbio 11 | 11,445
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

increased circulating fructosa... 13 | 13
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

osteosarcoma 6 | 7,950
Carcinoma 5 | 11,493
atypical teratoid / rhabdoid tumor 5 | 5,112
ovarian cancer 5 | 8,520
psoriasis 5 | 6,694
ependymoma 4 | 4,679
glioblastoma 4 | 5,792
group 3 medulloblastoma 4 | 4,104
lung cancer 4 | 4,740
medulloblastoma, large-cell 4 | 6,241
Astrocytoma, Pilocytic 3 | 3,081
Breast cancer 3 | 3,578
Cancer 3 | 2,499
Kidney cancer 3 | 2,613
Pick disease 3 | 1,894
adult high grade glioma 3 | 3,801
astrocytic glioma 3 | 2,597
colon cancer 3 | 1,478
ductal carcinoma in situ 3 | 1,745
gastric carcinoma 3 | 807
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
primitive neuroectodermal tumor 3 | 3,035
Autosomal recessive predisposition 2 | 1,442
Cognitive delay 2 | 608
Global developmental delay 2 | 608
Hepatomegaly 2 | 285
Malabsorption 2 | 82
Mental and motor retardation 2 | 608
Obesity 2 | 678
Short stature 2 | 531
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
acute myeloid leukemia 2 | 783
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
group 4 medulloblastoma 2 | 1,855
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primary Sjogren syndrome 2 | 735
tuberculosis 2 | 2,010
urothelial carcinoma 2 | 318
Abnormal pigmentation 1 | 25
Abnormality of female internal genitalia 1 | 13
Abnormality of the fingernails 1 | 51
Abnormality of the pharynx 1 | 19
Absence of secondary sex characteristics 1 | 22
Advanced bone age 1 | 35
Anorectal Malformations 1 | 8
Aplasia/Hypoplasia of the skin 1 | 16
Bone marrow hypocellularity 1 | 20
Cocaine Dependence 1 | 51
DYSKERATOSIS CONGENITA, AUTOSOMAL RECESSIVE 3 1 | 1
DYSKERATOSIS CONGENITA, AUTOSOMAL RECESSIVE, 3 1 | 1
Delayed Puberty 1 | 97
Dental caries 1 | 164
Diabetes Mellitus, Experimental 1 | 108
Dyskeratosis congenita 1 | 24
Endomyocardial Fibrosis 1 | 13
Esophageal Stenosis 1 | 15
Fatty Liver 1 | 70
Fatty liver disease 1 | 103
Fibrosis 1 | 44
Gestational diabetes 1 | 26
Gingival Diseases 1 | 19
Glucose Intolerance 1 | 19
Granulosa cell tumor 1 | 6
Gynecomastia 1 | 64
Hyperglycemia 1 | 137
Hyperlipidemia 1 | 43
Hyperpigmented macules 1 | 42
Hypertriglyceridemia result 1 | 37
Hypodontia 1 | 81
Hypoplastic-absent toenails 1 | 11
Impaired glucose tolerance 1 | 28
Insulin Resistance 1 | 72
Large elongated pulp chamber 1 | 14
Leukokeratosis 1 | 19
Leukoplakia, Oral 1 | 20
Low serum estradiol levels 1 | 22
Malignant Squamous Cell Neoplasm 1 | 17
Panic disorder 1 | 61
Periodontal Diseases 1 | 21
Peroxisome Biogenesis Disorder 1A (Zellweger) 1 | 12
Primary hypogonadism 1 | 37
Primary physiologic amenorrhea 1 | 55
Rotting teeth 1 | 73
Rough bone trabeculation 1 | 11
Sickle Cell Anemia 1 | 53
Skin Ulcer 1 | 48
Small testicle 1 | 75
Taurodontism 1 | 14
Tracheoesophageal Fistula 1 | 36
Urethral Stricture 1 | 18
hypopigmented skin patch 1 | 59
uncontrolled asthma 1 | 56

Tissue

Blood and immune system 13 | 16,909
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678
Cardiovascular System 12 | 15,192
Nervous System 12 | 16,725
Respiratory system 12 | 16,393

Target Family

Enzyme 6 | 4,145
Non-IDG 5 | 12,091
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytochrome b561 CYB561 Tbio Non-IDG -1.41422 21.1 62
Pleckstrin homology domain-containing family G member 1 PLEKHG1 Tdark Non-IDG -0.01154 0.50 56
Polypeptide N-acetylgalactosaminyltransferase 18 GALNT18 Tbio Enzyme -0.54647 3.29 37
Leptin receptor LEPR Tclin Non-IDG -3.01833 782.6 615
Peroxisomal biogenesis factor 3 PEX3 Tbio Non-IDG -1.79362 72.7 79
Protein FAM53B FAM53B Tbio Non-IDG -1.70473 50.6 24
Kynurenine formamidase AFMID Tbio Enzyme -1.65562 44.8 67
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial SIRT4 Tbio Epigenetic -2.14139 133.9 254
Telomerase Cajal body protein 1 WRAP53 Tbio Enzyme -1.50893 31.5 58
A-kinase anchor protein 9 AKAP9 Tbio Enzyme -2.22554 169.7 142