Development Level

Tbio 6 | 10,625
Tdark 3 | 7,003
Tchem 1 | 1,890
Tclin 1 | 602

IMPC Term

increased circulating fructosa... 11 | 11
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat/hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

atypical teratoid / rhabdoid tumor 6 | 4,369
osteosarcoma 6 | 7,933
ovarian cancer 6 | 8,484
glioblastoma 5 | 5,572
medulloblastoma, large-cell 5 | 6,234
psoriasis 5 | 6,685
Cancer 3 | 2,346
Carcinoma 3 | 2,147
Pick disease 3 | 1,893
adult high grade glioma 3 | 2,148
astrocytic glioma 3 | 2,241
colon cancer 3 | 1,475
ductal carcinoma in situ 3 | 1,745
gastric carcinoma 3 | 832
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
invasive ductal carcinoma 3 | 2,950
lung adenocarcinoma 3 | 2,713
lung cancer 3 | 4,466
medulloblastoma 3 | 1,524
pilocytic astrocytoma 3 | 3,086
posterior fossa group B ependymoma 3 | 1,530
primitive neuroectodermal tumor 3 | 3,031
Breast cancer 2 | 3,094
Metabolic syndrome X 2 | 155
Obesity 2 | 616
acute myeloid leukemia 2 | 780
cystic fibrosis 2 | 1,665
diabetes mellitus 2 | 1,663
ependymoma 2 | 2,514
group 4 medulloblastoma 2 | 1,875
malignant mesothelioma 2 | 3,162
oligodendroglioma 2 | 2,849
pancreatic cancer 2 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
primary Sjogren syndrome 2 | 789
tuberculosis 2 | 1,557
Acquired metabolic disease 1 | 267
Adrenoleukodystrophy, Neonatal 1 | 13
Amyotrophic Lateral Sclerosis 1 | 431
Anorexia nervosa 1 | 59
Arsenic Poisoning 1 | 59
Atopic dermatitis 1 | 944
Blood pressure finding 1 | 56
Cardiovascular system disease 1 | 194
Cocaine dependence 1 | 24
Dermatologic disorders 1 | 65
Diabetes Mellitus, Experimental 1 | 106
Diabetes Mellitus, Non-Insulin-Dependent 1 | 157
Fatty liver disease 1 | 84
Female infertility 1 | 28
Fibrosis 1 | 40
Gaucher disease type 3 1 | 76
Gestational Diabetes 1 | 17
Gout 1 | 93
Hyperglycemia 1 | 120
Hyperinsulinism 1 | 63
Hyperlipidemia 1 | 25
Hypertension 1 | 287
Hypertensive disease 1 | 193
Hypogonadism 1 | 70
Immunologic Deficiency Syndromes 1 | 16
Infantile Refsum Disease (disorder) 1 | 13
Infantile refsum disease 1 | 19
Infertility 1 | 163
Insulin Resistance 1 | 48
Kidney Diseases 1 | 86
Long QT syndrome 1 | 52
Long Qt Syndrome 11 1 | 1
Lung Neoplasms 1 | 171
Macroglobulinemia 1 | 17
Mammary Neoplasms 1 | 410
Panic disorder 1 | 55
Peripheral Neuropathy 1 | 303
Peroxisomal disease 1 | 20
Peroxisome biogenesis disorders 1 | 11
Pontocerebellar hypoplasia 1 | 29
Rhizomelic chondrodysplasia punctata 1 | 11
Romano-Ward Syndrome 1 | 12
Schistosomiasis 1 | 38
Systemic arterial pressure 1 | 56
Testicular cancer 1 | 24
Type 2 diabetes mellitus 1 | 189
Zellweger Syndrome 1 | 38
active Crohn's disease 1 | 918
active ulcerative colitis 1 | 477
adrenocortical carcinoma 1 | 1,427
astrocytoma 1 | 1,493
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 499
breast carcinoma 1 | 1,614
facioscapulohumeral dystrophy 1 | 286
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,988
non-small cell lung cancer 1 | 2,798
non-small cell lung carcinoma 1 | 413
pancreatic carcinoma 1 | 567
pituitary cancer 1 | 1,972
primary pancreatic ductal adenocarcinoma 1 | 1,271
progressive supranuclear palsy 1 | 674
spina bifida 1 | 1,064
substance-related disorder 1 | 105
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 11 | 17,995
Cardiovascular System 11 | 17,958
Digestive Tract 11 | 18,473
Endocrine System 11 | 18,512
Female tissues 11 | 18,647
Liver and Pancreas 11 | 18,136
Male tissues 11 | 17,969
Nervous System 11 | 18,561
Respiratory system 11 | 17,484
Skin and soft tissues 11 | 18,115
Urinary Tract 11 | 18,444

Target Family

Non-IDG 5 | 11,971
Enzyme 3 | 4,146
Epigenetic 1 | 242
Kinase 1 | 634
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytochrome b561 CYB561 Tbio Non-IDG -1.41910 20.4 45
Ras-related protein Rab-5C RAB5C Tbio Enzyme -1.13458 11.1 135
Polypeptide N-acetylgalactosaminyltransferase 18 GALNT18 Tdark Enzyme -0.28065 3.03 33
Leptin receptor LEPR Tclin Non-IDG -2.98449 751.7 530
Pleckstrin homology domain-containing family G member 1 PLEKHG1 Tdark Non-IDG 0.28 0.50 44
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial SIRT4 Tchem Epigenetic -2.02454 115.1 229
ADP-dependent glucokinase ADPGK Tbio Kinase -0.75433 6.95 123
A-kinase anchor protein 9 AKAP9 Tbio Enzyme -2.17812 161.8 105
Nuclear transcription factor Y subunit alpha NFYA Tbio Transcription Factor -2.04745 102.7 156
Peroxisomal biogenesis factor 3 PEX3 Tbio Non-IDG -1.74952 66.8 68