Development Level

Tbio 13 | 10,625
Tchem 2 | 1,890
Tdark 2 | 7,003

IMPC Phenotype

increased circulating free fat... 17 | 17
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat-hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

ovarian cancer 12 | 8,491
medulloblastoma, large-cell 7 | 6,234
glioblastoma 6 | 5,572
lung adenocarcinoma 6 | 2,714
osteosarcoma 6 | 7,933
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
invasive ductal carcinoma 5 | 2,950
lung cancer 5 | 4,473
subependymal giant cell astrocytoma 5 | 2,287
Multiple myeloma 4 | 1,327
breast carcinoma 4 | 1,614
diabetes mellitus 4 | 1,663
esophageal adenocarcinoma 4 | 737
malignant mesothelioma 4 | 3,163
medulloblastoma 4 | 1,524
non-small cell lung cancer 4 | 2,798
psoriasis 4 | 6,685
Cancer 3 | 2,346
adrenocortical carcinoma 3 | 1,427
atypical teratoid / rhabdoid tumor 3 | 4,369
interstitial cystitis 3 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
lung carcinoma 3 | 2,844
nasopharyngeal carcinoma 3 | 1,056
oligodendroglioma 3 | 2,849
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
pediatric high grade glioma 3 | 2,712
posterior fossa group B ependymoma 3 | 1,530
spina bifida 3 | 1,064
tuberculosis 3 | 1,563
ulcerative colitis 3 | 2,087
Adenocarcinoma 2 | 115
Alzheimer's disease 2 | 644
Breast cancer 2 | 3,098
Carcinoma 2 | 2,147
Common variable immunodeficiency 2 | 98
Crohn's disease 2 | 304
Duchenne muscular dystrophy 2 | 602
Lipid metabolism disorder 2 | 102
Schizophrenia 2 | 503
acute quadriplegic myopathy 2 | 1,157
astrocytoma 2 | 1,493
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
cystic fibrosis 2 | 1,670
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
juvenile dermatomyositis 2 | 1,189
nephrosclerosis 2 | 329
non primary Sjogren syndrome sicca 2 | 840
pilocytic astrocytoma 2 | 3,086
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,031
Age related macular degeneration 1 | 84
Aphasia 1 | 22
Brain disease 1 | 84
Candidiasis 1 | 48
Cardiomyopathy 1 | 110
Cardiovascular system disease 1 | 194
Carotid Artery Diseases 1 | 11
Cerebral amyloid angiopathy 1 | 9
Chylomicron retention disease 1 | 11
Combined oxidative phosphorylation deficiency 1 1 | 1
Coronary heart disease 1 | 59
Degenerative polyarthritis 1 | 93
Drug-Induced Liver Injury 1 | 118
Gastrointestinal Stromal Tumors 1 | 8
Hemophilia B 1 | 11
Hepatoencephalopathy due to combined oxidative phosphorylation deficiency type 1 1 | 1
Hyperglycemia 1 | 120
Hyperhomocysteinemia 1 | 34
Hyperlipidemia 1 | 25
Kidney cortex necrosis 1 | 2
Leigh disease 1 | 81
Leigh syndrome 1 | 34
Liver disease 1 | 219
Liver diseases 1 | 66
Lung Neoplasms 1 | 171
Lysosomal storage disease 1 | 11
MYELODYSPLASTIC SYNDROME 1 | 39
Microcephaly 1 | 149
Myocardial Infarction 1 | 126
Neoplastic Cell Transformation 1 | 81
Neoplastic Syndromes, Hereditary 1 | 48
Nerve Degeneration 1 | 73
Ovarian Cysts 1 | 34
Paraganglioma 1 | 12
Pathological accumulation of air in tissues 1 | 11
Persistent generalized lymphadenopathy 1 | 15
Phaeochromocytoma 1 | 20
Steatorrhea 1 | 20
Vitreous detachment 1 | 9
extra-adrenal pheochromocytoma 1 | 7
fascioscapulohumeral muscular dystrophy 1 | 100
head and neck cancer and chronic obstructive pulmonary disease 1 | 237
hereditary spastic paraplegia 1 | 313
non-inflammatory breast cancer 1 | 208
ovarian neoplasm 1 | 97
von Hippel-Lindau disease 1 | 11

Tissue

Blood and immune system 17 | 17,994
Cardiovascular System 17 | 17,957
Digestive Tract 17 | 18,472
Endocrine System 17 | 18,511
Female tissues 17 | 18,646
Liver and Pancreas 17 | 18,135
Male tissues 17 | 17,968
Nervous System 17 | 18,560
Respiratory system 17 | 17,483
Skin and soft tissues 17 | 18,114
Urinary Tract 17 | 18,443

Target Family

Non-IDG 9 | 11,969
Enzyme 7 | 4,146
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Intraflagellar transport protein 25 homolog HSPB11 Tbio Non-IDG -1.36468 21.9 56
DNA-directed RNA polymerases I, II, and III subunit RPABC3 POLR2H Tbio Enzyme -1.14104 13.5 159
AP-2 complex subunit alpha-2 AP2A2 Tbio Non-IDG -0.63932 4.63 109
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 RPN2 Tbio Enzyme -1.46978 30.0 91
Death-associated protein 1 DAP Tbio Non-IDG -2.28289 158.1 170
Integrin alpha-8 ITGA8 Tbio Non-IDG -1.30330 19.3 110
Rho guanine nucleotide exchange factor 4 ARHGEF4 Tbio Non-IDG -1.35105 25.1 107
Actin-binding LIM protein 1 ABLIM1 Tbio Non-IDG -1.05179 10.8 111
Peptidyl-prolyl cis-trans isomerase-like 3 PPIL3 Tbio Enzyme -0.79350 7.21 99
Coiled-coil domain-containing protein 120 CCDC120 Tdark Non-IDG -0.12494 1.42 86