Development Level

Tbio 34 | 11,651
Tchem 5 | 1,388
Tclin 2 | 612

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

increased circulating chloride... 41 | 41
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 27 | 11,493
glioblastoma 21 | 5,792
psoriasis 20 | 6,694
atypical teratoid / rhabdoid tumor 19 | 5,112
ovarian cancer 19 | 8,520
ependymoma 18 | 4,679
medulloblastoma, large-cell 18 | 6,241
osteosarcoma 18 | 7,950
lung cancer 16 | 4,740
Astrocytoma, Pilocytic 15 | 3,081
adult high grade glioma 15 | 3,801
group 3 medulloblastoma 15 | 4,104
primitive neuroectodermal tumor 13 | 3,035
astrocytic glioma 12 | 2,597
Kidney cancer 11 | 2,613
oligodendroglioma 11 | 2,850
subependymal giant cell astrocytoma 11 | 2,287
lung carcinoma 9 | 2,843
Autosomal recessive predisposition 8 | 1,442
Breast cancer 8 | 3,578
Pick disease 8 | 1,894
Schizophrenia 8 | 1,160
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
non-small cell lung cancer 8 | 2,890
pituitary cancer 8 | 1,972
Bipolar Disorder 7 | 666
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
Alzheimer's disease 6 | 658
Intellectual disability 6 | 1,016
lung adenocarcinoma 6 | 2,716
malignant mesothelioma 6 | 3,232
pancreatic cancer 6 | 2,398
primary pancreatic ductal adenocarcinoma 6 | 1,109
Cancer 5 | 2,499
Epilepsy 5 | 792
juvenile dermatomyositis 5 | 1,187
pediatric high grade glioma 5 | 1,064
Atopic dermatitis 4 | 952
Autistic Disorder 4 | 364
Disease Models, Animal 4 | 155
Large intestine cancer 4 | 126
Liver cancer 4 | 604
Multiple myeloma 4 | 1,332
Rheumatoid arthritis 4 | 1,191
adrenocortical carcinoma 4 | 1,428
astrocytoma 4 | 1,146
breast carcinoma 4 | 1,638
esophageal adenocarcinoma 4 | 737
gastric carcinoma 4 | 807
group 4 medulloblastoma 4 | 1,855
invasive ductal carcinoma 4 | 2,951
non primary Sjogren syndrome sicca 4 | 891
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Amyotrophic lateral sclerosis 3 | 451
Autism spectrum disorder 3 | 101
Constipation 3 | 181
Dementia 3 | 175
Depressive disorder 3 | 409
Failure to gain weight 3 | 365
Kidney disease 3 | 430
Major Depressive Disorder 3 | 301
Mental Depression 3 | 333
Mood Disorders 3 | 184
Motor neuron disease 3 | 49
Obesity 3 | 678
Parkinson's disease 3 | 392
Pediatric failure to thrive 3 | 365
Systemic lupus erythematosus 3 | 194
Vascular disease 3 | 319
Waldenstrons macroglobulinemia 3 | 765
acute myeloid leukemia 3 | 783
acute quadriplegic myopathy 3 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
cutaneous lupus erythematosus 3 | 1,057
diabetes mellitus 3 | 1,728
interstitial cystitis 3 | 2,312
tuberculosis 3 | 2,010
ulcerative colitis 3 | 1,819
Cerebrovascular disease 2 | 238
Down syndrome 2 | 499
Duchenne muscular dystrophy 2 | 601
Endometrial cancer 2 | 311
Hypertension 2 | 396
Melanoma 2 | 711
Multiple Sclerosis 2 | 540
Neurodegenerative disease 2 | 414
Polycystic ovary syndrome 2 | 360
Prostatic Neoplasms 2 | 495
Seizures 2 | 596
Skin cancer 2 | 469
Strabismus 2 | 270
aldosterone-producing adenoma 2 | 665
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
limb girdle muscular dystrophy 2A 2 | 213
nasopharyngeal carcinoma 2 | 1,058
periodontitis 2 | 293
progressive supranuclear palsy 2 | 676
sonic hedgehog group medulloblastoma 2 | 467

Tissue

Digestive Tract 40 | 17,369
Endocrine System 40 | 18,159
Liver and Pancreas 40 | 16,750
Skin and soft tissues 40 | 17,230
Blood and immune system 39 | 16,909
Female tissues 39 | 17,400
Male tissues 38 | 17,142
Nervous System 37 | 16,725
Urinary Tract 36 | 16,678
Cardiovascular System 35 | 15,192
Respiratory system 35 | 16,393

Target Family

Non-IDG 25 | 12,091
Enzyme 8 | 4,145
Transcription Factor 3 | 1,400
GPCR 2 | 408
Epigenetic 1 | 242
Ion Channel 1 | 344
Kinase 1 | 634

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
5-hydroxytryptamine receptor 7 HTR7 Tclin GPCR -4.15964 13643.7 259
Vimentin VIM Tbio Non-IDG -3.27433 1830.9 2236
Glutamate decarboxylase 2 GAD2 Tbio Enzyme -3.03047 1065.4 459
Disks large homolog 4 DLG4 Tchem Non-IDG -2.98766 883.9 559
Enteropeptidase TMPRSS15 Tchem Enzyme -2.78466 584.5 140
EH domain-containing protein 1 EHD1 Tbio Non-IDG -2.69664 478.0 113
Ectonucleoside triphosphate diphosphohydrolase 1 ENTPD1 Tbio Enzyme -2.68249 518.8 505
Polycystin-1 PKD1 Tbio Non-IDG -2.60276 379.9 123
Dachshund homolog 1 DACH1 Tbio Non-IDG -2.51016 323.1 190
Myosin-binding protein C, cardiac-type MYBPC3 Tbio Non-IDG -2.45618 287.6 139