Development Level

Tbio 9 | 11,445
Tchem 2 | 1,598
Tclin 2 | 613
Tdark 2 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

increased circulating aspartat... 15 | 15
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 11 | 11,493
ovarian cancer 7 | 8,520
psoriasis 7 | 6,694
osteosarcoma 6 | 7,950
medulloblastoma, large-cell 5 | 6,241
Breast cancer 4 | 3,578
Kidney cancer 4 | 2,613
atypical teratoid / rhabdoid tumor 4 | 5,112
diabetes mellitus 4 | 1,728
ependymoma 4 | 4,679
glioblastoma 4 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
malignant mesothelioma 4 | 3,232
pituitary cancer 4 | 1,972
tuberculosis 4 | 2,010
Astrocytoma, Pilocytic 3 | 3,081
Cancer 3 | 2,499
Diabetes Mellitus, Non-Insulin-Dependent 3 | 145
Diabetes Mellitus, Type 2 3 | 142
Obesity 3 | 678
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
lung adenocarcinoma 3 | 2,716
lung cancer 3 | 4,740
primitive neuroectodermal tumor 3 | 3,035
Acquired metabolic disease 2 | 336
Ataxia, Appendicular 2 | 25
Ataxia, Truncal 2 | 21
Atrophy of cerebellum 2 | 103
Autosomal recessive predisposition 2 | 1,442
Bipolar Disorder 2 | 666
Cerebellar Ataxia 2 | 304
Cerebellar degeneration 2 | 103
Fatty liver disease 2 | 103
Infratentorial atrophy 2 | 103
Leukemia 2 | 104
Neurodegenerative disease 2 | 414
Parkinson's disease 2 | 392
Schizophrenia 2 | 1,160
Type 2 diabetes mellitus 2 | 272
acute myeloid leukemia 2 | 783
adult high grade glioma 2 | 3,801
aldosterone-producing adenoma 2 | 665
astrocytic glioma 2 | 2,597
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
ductal carcinoma in situ 2 | 1,745
group 4 medulloblastoma 2 | 1,855
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
ulcerative colitis 2 | 1,819
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 1 | 21
Absence of secondary sex characteristics 1 | 22
CHOLESTASIS, PROGRESSIVE FAMILIAL INTRAHEPATIC, 5 1 | 1
Calculus in biliary tract 1 | 2
Cerebellar Dysmetria 1 | 56
Cholelithiasis Prevention 1 | 1
Cholestasis of pregnancy 1 | 5
Ciliopathy 1 | 71
Cone dystrophy 1 | 71
Deglutition Disorders 1 | 132
Delayed Puberty 1 | 97
Diabetes Mellitus, Experimental 1 | 108
Diabetes Mellitus, Noninsulin-Dependent 1 | 31
Dysmetric saccades 1 | 9
Extravasation of Diagnostic and Therapeutic Materials 1 | 6
Fatty Liver 1 | 70
Fibrosis 1 | 44
Fundus dystrophy 1 | 83
Gestational diabetes 1 | 26
Glucose Intolerance 1 | 19
Granulosa cell tumor 1 | 6
Gynecomastia 1 | 64
Hyperglycemia 1 | 137
Hyperlipidemia 1 | 43
Hypertriglyceridemia result 1 | 37
Impaired glucose tolerance 1 | 28
Insulin Resistance 1 | 72
Intestinal Neoplasms 1 | 12
Intrahepatic cholestasis 1 | 20
Low serum estradiol levels 1 | 22
Multiple system atrophy 1 | 29
Muscle Cramp 1 | 55
Muscle Rigidity 1 | 49
PARKINSON DISEASE, LATE-ONSET 1 | 20
Postural instability 1 | 19
Primary cholangitis 1 | 2
Primary hypogonadism 1 | 37
Primary physiologic amenorrhea 1 | 55
Progressive cerebellar ataxia 1 | 13
Progressive intrahepatic cholestasis 1 | 4
Restless legs syndrome 1 | 27
Small testicle 1 | 75
Spinocerebellar ataxia type 1 1 | 16
Spinocerebellar ataxia type 2 1 | 23
ventricular septal defect 1 | 20

Tissue

Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678
Blood and immune system 14 | 16,909
Cardiovascular System 14 | 15,192
Nervous System 14 | 16,725

Target Family

Non-IDG 9 | 12,091
Kinase 2 | 634
Enzyme 1 | 4,145
Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Anoctamin-10 ANO10 Tbio Non-IDG -1.22069 14.6 54
Protein AF-9 MLLT3 Tbio Non-IDG -1.99555 93.8 210
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit DDOST Tchem Enzyme -1.60313 44.1 140
Zinc transporter 8 SLC30A8 Tbio Transporter -2.20313 168.0 122
Transcription factor GATA-5 GATA5 Tbio Transcription Factor -1.95925 86.1 183
Leptin receptor LEPR Tclin Non-IDG -3.01833 782.6 615
Leucine-rich repeat serine/threonine-protein kinase 1 LRRK1 Tbio Kinase -1.33128 18.1 134
AP-3 complex subunit sigma-2 AP3S2 Tdark Non-IDG -0.27930 1.66 66
Protein FAM104A FAM104A Tdark Non-IDG 0.00000 0.00000 5
TBC1 domain family member 22A TBC1D22A Tbio Non-IDG -0.34282 1.72 112