Development Level

Tbio 81 | 10,625
Tdark 18 | 7,003
Tchem 15 | 1,890
Tclin 5 | 602

IMPC Term

increased circulating alkaline... 119 | 119
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat/hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

ovarian cancer 64 | 8,492
psoriasis 62 | 6,685
glioblastoma 56 | 5,572
medulloblastoma, large-cell 56 | 6,234
osteosarcoma 56 | 7,933
atypical teratoid / rhabdoid tumor 38 | 4,369
pilocytic astrocytoma 38 | 3,086
lung cancer 37 | 4,473
pediatric high grade glioma 36 | 2,712
primitive neuroectodermal tumor 32 | 3,031
malignant mesothelioma 31 | 3,163
lung adenocarcinoma 29 | 2,714
intraductal papillary-mucinous carcinoma (IPMC) 28 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 27 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,289
invasive ductal carcinoma 27 | 2,950
astrocytic glioma 26 | 2,241
oligodendroglioma 26 | 2,849
subependymal giant cell astrocytoma 26 | 2,287
Breast cancer 24 | 3,099
non-small cell lung cancer 24 | 2,798
Cancer 23 | 2,346
lung carcinoma 22 | 2,844
ependymoma 21 | 2,514
group 3 medulloblastoma 19 | 2,254
pituitary cancer 19 | 1,972
Pick disease 18 | 1,893
breast carcinoma 18 | 1,614
cystic fibrosis 18 | 1,670
adult high grade glioma 17 | 2,148
posterior fossa group A ependymoma 17 | 1,511
ductal carcinoma in situ 16 | 1,745
adrenocortical carcinoma 15 | 1,427
pancreatic cancer 15 | 2,300
ulcerative colitis 15 | 2,087
medulloblastoma 14 | 1,524
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,795
Carcinoma 13 | 2,147
colon cancer 13 | 1,475
diabetes mellitus 13 | 1,663
juvenile dermatomyositis 13 | 1,189
tuberculosis 13 | 1,563
acute myeloid leukemia 12 | 785
acute quadriplegic myopathy 12 | 1,157
group 4 medulloblastoma 12 | 1,875
interstitial cystitis 12 | 2,299
primary pancreatic ductal adenocarcinoma 11 | 1,271
nasopharyngeal carcinoma 10 | 1,056
sonic hedgehog group medulloblastoma 10 | 1,482
spina bifida 10 | 1,064
Atopic dermatitis 9 | 944
active Crohn's disease 9 | 918
cutaneous lupus erythematosus 9 | 1,056
dermatomyositis 9 | 967
esophageal adenocarcinoma 9 | 737
Alzheimer's disease 8 | 644
astrocytoma 8 | 1,493
posterior fossa group B ependymoma 8 | 1,530
Down syndrome 7 | 548
Multiple myeloma 7 | 1,328
Parkinson's disease 7 | 364
Rheumatoid Arthritis 7 | 1,171
Schizophrenia 7 | 503
active ulcerative colitis 7 | 477
aldosterone-producing adenoma 7 | 664
atypical teratoid/rhabdoid tumor 7 | 1,095
non primary Sjogren syndrome sicca 7 | 840
primary Sjogren syndrome 7 | 789
Duchenne muscular dystrophy 6 | 602
Intellectual disability 6 | 573
Multiple Sclerosis 6 | 498
non-inflammatory breast cancer 6 | 208
Amyotrophic Lateral Sclerosis 5 | 432
Kidney disease 5 | 397
Neurodegenerative disease 5 | 383
Neuropathy 5 | 210
Peripheral Neuropathy 5 | 303
Prostatic Neoplasms 5 | 471
Vascular disease 5 | 281
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 499
gastric carcinoma 5 | 832
mucosa-associated lymphoid tissue lymphoma 5 | 480
tuberculosis and treatment for 6 months 5 | 686
Asthma 4 | 349
Colorectal Neoplasms 4 | 217
Diabetes Mellitus, Non-Insulin-Dependent 4 | 161
Endometriosis 4 | 535
Epilepsy 4 | 346
Glaucoma 4 | 135
Hypertension 4 | 293
Hyperthyroidism 4 | 50
IGA Glomerulonephritis 4 | 454
Leber congenital amaurosis 4 | 72
Mammary Neoplasms 4 | 410
Obesity 4 | 616
Polycystic Ovary Syndrome 4 | 335
fibroadenoma 4 | 557
non-small cell lung carcinoma 4 | 413
sarcoidosis 4 | 368
nephrosclerosis 3 | 329

Tissue

Cardiovascular System 118 | 17,958
Digestive Tract 118 | 18,473
Liver and Pancreas 118 | 18,136
Nervous System 118 | 18,561
Blood and immune system 117 | 17,995
Endocrine System 117 | 18,512
Male tissues 117 | 17,969
Skin and soft tissues 117 | 18,115
Urinary Tract 117 | 18,444
Female tissues 116 | 18,647
Respiratory system 116 | 17,484

Target Family

Non-IDG 70 | 11,969
Enzyme 24 | 4,146
Transcription Factor 7 | 1,400
Transporter 7 | 473
Epigenetic 4 | 242
Kinase 4 | 634
GPCR 2 | 408
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein Hook homolog 3 HOOK3 Tbio Non-IDG -1.18684 0.00000 55
Protein FAM134C FAM134C Tdark Non-IDG 0.30 0.44 50
DnaJ homolog subfamily C member 17 DNAJC17 Tdark Non-IDG -0.04079 1.12 105
HBS1-like protein HBS1L Tbio Non-IDG -2.52098 316.2 144
Transmembrane protein 106B TMEM106B Tbio Non-IDG -1.43965 28.5 82
Unconventional myosin-VIIa MYO7A Tbio Non-IDG -2.10835 131.7 114
Osteoclast stimulatory transmembrane protein OCSTAMP Tdark Non-IDG -0.77309 6.79 11
N-acetylgalactosamine kinase GALK2 Tbio Kinase -1.24033 16.1 163
Protein BEX2 BEX2 Tbio Non-IDG -1.33698 24.3 36
BTB/POZ domain-containing protein 9 BTBD9 Tbio Non-IDG -1.30579 21.1 87