Development Level

Tbio 39 | 10,625
Tchem 8 | 1,890
Tdark 5 | 7,003

Collection

Eligible Kinase Proteins 2 | 134
Eligible Ion Channel Proteins 1 | 117
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

increased bone mineral density 52 | 52
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat/hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

osteosarcoma 29 | 7,933
ovarian cancer 28 | 8,484
lung cancer 22 | 4,466
medulloblastoma, large-cell 22 | 6,234
glioblastoma 21 | 5,572
psoriasis 18 | 6,685
atypical teratoid / rhabdoid tumor 13 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,289
lung carcinoma 11 | 2,844
malignant mesothelioma 11 | 3,162
pilocytic astrocytoma 11 | 3,086
primitive neuroectodermal tumor 11 | 3,031
Breast cancer 10 | 3,094
Cancer 10 | 2,346
astrocytoma 10 | 1,493
group 4 medulloblastoma 10 | 1,875
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,956
pituitary cancer 10 | 1,972
subependymal giant cell astrocytoma 10 | 2,287
Carcinoma 9 | 2,147
cystic fibrosis 9 | 1,665
invasive ductal carcinoma 9 | 2,950
lung adenocarcinoma 9 | 2,713
pediatric high grade glioma 9 | 2,712
pancreatic cancer 8 | 2,300
primary pancreatic ductal adenocarcinoma 8 | 1,271
ulcerative colitis 8 | 2,087
Rheumatoid Arthritis 7 | 1,160
diabetes mellitus 7 | 1,663
gastric carcinoma 7 | 832
group 3 medulloblastoma 7 | 2,254
interstitial cystitis 7 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,988
spina bifida 7 | 1,064
adrenocortical carcinoma 6 | 1,427
ductal carcinoma in situ 6 | 1,745
non-small cell lung cancer 6 | 2,798
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
tuberculosis 6 | 1,557
Alzheimer's disease 5 | 644
adult high grade glioma 5 | 2,148
breast carcinoma 5 | 1,614
colon cancer 5 | 1,475
medulloblastoma 5 | 1,524
posterior fossa group B ependymoma 5 | 1,530
sonic hedgehog group medulloblastoma 5 | 1,482
Pick disease 4 | 1,893
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 499
cutaneous lupus erythematosus 4 | 1,056
ependymoma 4 | 2,514
esophageal adenocarcinoma 4 | 737
posterior fossa group A ependymoma 4 | 1,511
primary Sjogren syndrome 4 | 789
Atopic dermatitis 3 | 944
Duchenne muscular dystrophy 3 | 602
Intellectual disability 3 | 573
Neurodegenerative disease 3 | 383
Osteoporosis 3 | 257
active Crohn's disease 3 | 918
active ulcerative colitis 3 | 477
acute quadriplegic myopathy 3 | 1,157
astrocytic glioma 3 | 2,241
juvenile dermatomyositis 3 | 1,189
nasopharyngeal carcinoma 3 | 1,056
oligodendroglioma 3 | 2,849
tuberculosis and treatment for 6 months 3 | 686
Acquired metabolic disease 2 | 267
Becker muscular dystrophy 2 | 187
Colonic Neoplasms 2 | 126
Corneal disease 2 | 32
Heart conduction disease 2 | 65
Heart disease 2 | 279
Kluver-Bucy syndrome 2 | 6
Malignant neoplasm of prostate 2 | 67
Mammary Neoplasms 2 | 410
Mucopolysaccharidosis 2 | 24
Mucopolysaccharidosis III 2 | 6
Multiple myeloma 2 | 1,327
Obesity 2 | 616
Pain 2 | 70
Palmoplantar keratosis 2 | 36
Paraplegia 2 | 71
Parkinson's disease 2 | 364
Schizophrenia 2 | 501
Stomach Neoplasms 2 | 282
Vascular disease 2 | 281
Waldenstrons macroglobulinemia 2 | 765
atypical teratoid/rhabdoid tumor 2 | 1,095
chronic lymphosyte leukemia 2 | 232
chronic rhinosinusitis 2 | 512
dermatomyositis 2 | 933
head and neck cancer 2 | 270
hereditary spastic paraplegia 2 | 313
interstitial lung disease 2 | 291
nephrosclerosis 2 | 329
tuberculosis and treatment for 3 months 2 | 327
urothelial carcinoma 2 | 318
Diabetic Nephropathy 1 | 37
Hypokalemia 1 | 40
Lung Diseases, Interstitial 1 | 15

Tissue

Blood and immune system 52 | 17,995
Digestive Tract 52 | 18,473
Female tissues 52 | 18,647
Liver and Pancreas 52 | 18,136
Nervous System 52 | 18,561
Urinary Tract 52 | 18,444
Cardiovascular System 51 | 17,958
Endocrine System 51 | 18,512
Male tissues 51 | 17,969
Respiratory system 51 | 17,484
Skin and soft tissues 51 | 18,115

Target Family

Non-IDG 26 | 11,971
Enzyme 10 | 4,146
Transcription Factor 5 | 1,400
Kinase 4 | 634
Transporter 3 | 473
Epigenetic 2 | 242
GPCR 1 | 406
Ion Channel 1 | 341

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tumor necrosis factor receptor superfamily member 9 TNFRSF9 Tbio Non-IDG -2.71753 714.2 490
Zinc transporter ZIP5 SLC39A5 Tbio Transporter -1.03936 12.4 60
Testis development-related protein TDRP Tbio Non-IDG -0.57113 5.48 36
Histone-lysine N-methyltransferase SETD1A SETD1A Tbio Epigenetic -2.53375 346.3 108
Xylulose kinase XYLB Tbio Kinase -1.93370 89.0 67
Anaphase-promoting complex subunit CDC26 CDC26 Tbio Enzyme -0.67669 4.56 45
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein NOS1AP Tbio Enzyme -2.09236 133.4 142
Phospholipase DDHD1 DDHD1 Tbio Enzyme -1.15514 15.0 18
Protein spinster homolog 2 SPNS2 Tbio Non-IDG -1.29998 23.3 69
DNA-binding protein SATB1 SATB1 Tbio Transcription Factor -2.19863 197.9 293