Development Level

Tbio 11 | 10,625
Tdark 1 | 7,003

IMPC Term

increased Ly6C high monocyte n... 12 | 12
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat/hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

ovarian cancer 8 | 8,484
osteosarcoma 5 | 7,933
astrocytic glioma 4 | 2,241
glioblastoma 4 | 5,572
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
medulloblastoma, large-cell 4 | 6,234
psoriasis 4 | 6,685
Breast cancer 3 | 3,094
active Crohn's disease 3 | 918
atypical teratoid / rhabdoid tumor 3 | 4,369
ependymoma 3 | 2,514
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,289
lung cancer 3 | 4,466
oligodendroglioma 3 | 2,849
primitive neuroectodermal tumor 3 | 3,031
Carcinoma 2 | 2,147
Down syndrome 2 | 548
Intellectual disability 2 | 573
Multiple myeloma 2 | 1,327
adult high grade glioma 2 | 2,148
ductal carcinoma in situ 2 | 1,745
group 3 medulloblastoma 2 | 2,254
lung adenocarcinoma 2 | 2,713
pituitary cancer 2 | 1,972
spina bifida 2 | 1,064
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis and treatment for 6 months 2 | 686
ulcerative colitis 2 | 2,087
Aagenaes syndrome 1 | 2
Atopic dermatitis 1 | 944
Autistic Disorder 1 | 320
Benign paroxysmal positional nystagmus 1 | 13
Bipolar Disorder 1 | 266
CONGENITAL DISORDER OF GLYCOSYLATION, TYPE IIl 1 | 1
Campylobacteriosis 1 | 12
Cancer 1 | 2,346
Congenital disorder of glycosylation 1 | 53
Congenital hypothyroidism 1 | 20
Dental caries 1 | 67
Disease of anatomical entity 1 | 25
Fundus dystrophy 1 | 77
Gestational choriocarcinoma 1 | 3
Glaucoma 1 | 134
Goiter 1 | 27
Gonadal dysgenesis XX type deafness 1 | 4
Hypohidrosis 1 | 13
Hypothyroidism 1 | 89
Legionellosis 1 | 4
Leprosy 1 | 77
Localized scleroderma 1 | 9
MENTAL RETARDATION, AUTOSOMAL RECESSIVE 18 1 | 1
Major Depressive Disorder 1 | 106
Mental depression 1 | 58
Oculomotor nerve paralysis 1 | 2
PERRAULT SYNDROME 3 1 | 1
Perrault syndrome 1 | 12
Persian Gulf Syndrome 1 | 2
Poliomyelitis 1 | 11
Poor school performance 1 | 13
Posterior amorphous corneal dystrophy 1 | 9
Premature ovarian failure 1 | 64
Rheumatoid Arthritis 1 | 1,160
SHAHEEN SYNDROME 1 | 1
Schizophrenia 1 | 501
Sensorineural hearing loss 1 | 107
Skin lipoma 1 | 2
Thyroid Dyshormonogenesis 5 1 | 1
Trigeminal neuralgia 1 | 12
Type 2 diabetes mellitus 1 | 189
Weight Gain 1 | 87
active ulcerative colitis 1 | 477
acute quadriplegic myopathy 1 | 1,157
adrenocortical carcinoma 1 | 1,427
colon cancer 1 | 1,475
cutaneous lupus erythematosus 1 | 1,056
cystic fibrosis 1 | 1,665
diabetes mellitus 1 | 1,663
facioscapulohumeral dystrophy 1 | 286
group 4 medulloblastoma 1 | 1,875
head and neck cancer 1 | 270
hepatocellular carcinoma 1 | 532
invasive ductal carcinoma 1 | 2,950
juvenile dermatomyositis 1 | 1,189
lung carcinoma 1 | 2,844
malignant mesothelioma 1 | 3,162
nasopharyngeal carcinoma 1 | 1,056
non-small cell lung cancer 1 | 2,798
non-small cell lung carcinoma 1 | 413
pancreatic cancer 1 | 2,300
pancreatic carcinoma 1 | 567
pilocytic astrocytoma 1 | 3,086
posterior fossa group B ependymoma 1 | 1,530
primary pancreatic ductal adenocarcinoma 1 | 1,271
sonic hedgehog group medulloblastoma 1 | 1,482
substance-related disorder 1 | 105
tuberculosis 1 | 1,557
uncontrolled asthma 1 | 67
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 12 | 17,995
Cardiovascular System 12 | 17,958
Digestive Tract 12 | 18,473
Endocrine System 12 | 18,512
Female tissues 12 | 18,647
Liver and Pancreas 12 | 18,136
Male tissues 12 | 17,969
Nervous System 12 | 18,561
Respiratory system 12 | 17,484
Skin and soft tissues 12 | 18,115
Urinary Tract 12 | 18,444

Target Family

Enzyme 6 | 4,146
Non-IDG 4 | 11,971
Transcription Factor 2 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Polypeptide N-acetylgalactosaminyltransferase 18 GALNT18 Tdark Enzyme -0.28065 3.03 33
Mediator of RNA polymerase II transcription subunit 23 MED23 Tbio Enzyme -1.41952 30.0 128
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 AGAP1 Tbio Enzyme -0.77118 9.19 84
Methyl-CpG-binding domain protein 1 MBD1 Tbio Transcription Factor -2.19366 164.7 282
Conserved oligomeric Golgi complex subunit 6 COG6 Tbio Non-IDG -1.56291 38.9 67
Unconventional myosin-X MYO10 Tbio Non-IDG -1.43593 32.9 38
Dual oxidase maturation factor 2 DUOXA2 Tbio Enzyme -1.27171 17.0 74
Rho guanine nucleotide exchange factor 1 ARHGEF1 Tbio Non-IDG -2.86701 765.4 170
GDP-mannose 4,6 dehydratase GMDS Tbio Enzyme -2.00846 105.0 102
ATP-dependent Clp protease proteolytic subunit, mitochondrial CLPP Tbio Enzyme -2.64704 459.3 168