Development Level

Tbio 52 | 11,445
Tchem 10 | 1,598
Tdark 10 | 6,588
Tclin 7 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125
GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

improved glucose tolerance 79 | 79
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 51 | 11,493
ovarian cancer 39 | 8,520
glioblastoma 36 | 5,792
osteosarcoma 33 | 7,950
medulloblastoma, large-cell 31 | 6,241
atypical teratoid / rhabdoid tumor 29 | 5,112
psoriasis 29 | 6,694
lung cancer 26 | 4,740
ependymoma 22 | 4,679
adult high grade glioma 21 | 3,801
malignant mesothelioma 20 | 3,232
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,955
pancreatic cancer 19 | 2,398
Astrocytoma, Pilocytic 18 | 3,081
group 3 medulloblastoma 18 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
lung adenocarcinoma 17 | 2,716
non-small cell lung cancer 17 | 2,890
Breast cancer 16 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
lung carcinoma 15 | 2,843
oligodendroglioma 15 | 2,850
primitive neuroectodermal tumor 15 | 3,035
invasive ductal carcinoma 14 | 2,951
Cancer 13 | 2,499
Kidney cancer 13 | 2,613
astrocytic glioma 13 | 2,597
Autosomal recessive predisposition 12 | 1,442
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
subependymal giant cell astrocytoma 11 | 2,287
adrenocortical carcinoma 10 | 1,428
diabetes mellitus 10 | 1,728
interstitial cystitis 10 | 2,312
pituitary cancer 10 | 1,972
colon cancer 9 | 1,478
cystic fibrosis 9 | 1,696
tuberculosis 9 | 2,010
Epilepsy 8 | 792
Schizophrenia 8 | 1,160
acute myeloid leukemia 8 | 783
group 4 medulloblastoma 8 | 1,855
Hypertension 7 | 396
Pick disease 7 | 1,894
ductal carcinoma in situ 7 | 1,745
juvenile dermatomyositis 7 | 1,187
primary pancreatic ductal adenocarcinoma 7 | 1,109
Bipolar Disorder 6 | 666
Liver cancer 6 | 604
Muscle hypotonia 6 | 571
Rheumatoid arthritis 6 | 1,191
active Crohn's disease 6 | 922
breast carcinoma 6 | 1,638
esophageal adenocarcinoma 6 | 737
pediatric high grade glioma 6 | 1,064
ulcerative colitis 6 | 1,819
Duchenne muscular dystrophy 5 | 601
Obesity 5 | 678
Parkinson's disease 5 | 392
Polycystic ovary syndrome 5 | 360
astrocytoma 5 | 1,146
cutaneous lupus erythematosus 5 | 1,057
spina bifida 5 | 1,074
Arthritis, Juvenile 4 | 126
Asthma 4 | 385
Atopic dermatitis 4 | 952
Depressive disorder 4 | 409
Juvenile arthritis 4 | 126
Multiple myeloma 4 | 1,332
Neuropathy 4 | 261
Orbital separation excessive 4 | 244
Seizures 4 | 596
Short stature 4 | 531
Skin cancer 4 | 469
Type 2 diabetes mellitus 4 | 272
acute quadriplegic myopathy 4 | 1,158
aldosterone-producing adenoma 4 | 665
gastric carcinoma 4 | 807
non-small cell lung carcinoma 4 | 317
sonic hedgehog group medulloblastoma 4 | 467
Allergic hypersensitivity disease 3 | 126
Alzheimer's disease 3 | 658
Cerebrovascular disease 3 | 238
Dementia 3 | 175
Endometriosis 3 | 540
Hepatomegaly 3 | 285
Hypoglycemia 3 | 152
Kidney disease 3 | 430
Major Depressive Disorder 3 | 301
Male infertility 3 | 206
Melanoma 3 | 711
Mental Depression 3 | 333
Mood Disorders 3 | 184
Prostatic Neoplasms 3 | 495
Unipolar Depression 3 | 250
active ulcerative colitis 3 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
fibroadenoma 3 | 559
gastric cancer 3 | 459
hepatocellular carcinoma 3 | 547
medulloblastoma 3 | 720

Tissue

Endocrine System 78 | 18,159
Liver and Pancreas 76 | 16,750
Digestive Tract 75 | 17,369
Female tissues 75 | 17,400
Skin and soft tissues 74 | 17,230
Male tissues 73 | 17,142
Urinary Tract 72 | 16,678
Blood and immune system 71 | 16,909
Cardiovascular System 70 | 15,192
Nervous System 70 | 16,725
Respiratory system 70 | 16,393

Target Family

Non-IDG 49 | 12,091
Enzyme 14 | 4,145
GPCR 4 | 408
Transporter 4 | 473
Kinase 3 | 634
Transcription Factor 3 | 1,400
Ion Channel 1 | 344
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
43 kDa receptor-associated protein of the synapse RAPSN Tbio Non-IDG -2.09902 132.1 134
Harmonin USH1C Tbio Non-IDG -2.10689 124.7 188
SLIT and NTRK-like protein 1 SLITRK1 Tbio Non-IDG -2.74906 555.5 206
Septin-5 SEPT5 Tbio Non-IDG -1.71017 49.4 178
Sn1-specific diacylglycerol lipase alpha DAGLA Tchem Enzyme -1.11500 11.4 129
C-X-C chemokine receptor type 2 CXCR2 Tchem GPCR -2.87313 723.9 643
Transmembrane protein 116 TMEM116 Tdark Non-IDG 1.00 0.10 14
ADP/ATP translocase 1 SLC25A4 Tbio Transporter -2.07841 114.8 103
Somatostatin SST Tbio Non-IDG -4.14886 13572.0 397
Serine/threonine-protein kinase N3 PKN3 Tbio Kinase -1.19026 15.5 133