Development Level

Tbio 18 | 11,651
Tdark 5 | 6,593
Tchem 2 | 1,388
Tclin 1 | 612

IMPC Phenotype

impaired righting response 26 | 26
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 16 | 11,493
psoriasis 15 | 6,694
osteosarcoma 14 | 7,950
ovarian cancer 14 | 8,519
glioblastoma 13 | 5,792
Astrocytoma, Pilocytic 11 | 3,081
ependymoma 11 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
medulloblastoma, large-cell 11 | 6,241
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,290
Breast cancer 9 | 3,577
lung adenocarcinoma 9 | 2,716
lung cancer 9 | 4,740
lung carcinoma 9 | 2,843
adult high grade glioma 8 | 3,801
interstitial cystitis 8 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,954
non-small cell lung cancer 8 | 2,890
atypical teratoid / rhabdoid tumor 7 | 5,112
colon cancer 7 | 1,478
Cancer 6 | 2,499
invasive ductal carcinoma 6 | 2,950
malignant mesothelioma 6 | 3,232
pancreatic cancer 6 | 2,398
pituitary cancer 6 | 1,972
Kidney cancer 5 | 2,613
Schizophrenia 5 | 1,160
cystic fibrosis 5 | 1,695
group 3 medulloblastoma 5 | 4,104
oligodendroglioma 5 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
primary Sjogren syndrome 5 | 735
subependymal giant cell astrocytoma 5 | 2,287
Autosomal recessive predisposition 4 | 1,442
Colorectal Neoplasms 4 | 243
Liver Cirrhosis 4 | 181
Rheumatoid arthritis 4 | 1,191
Sensorineural Hearing Loss (disorder) 4 | 284
breast carcinoma 4 | 1,637
cutaneous lupus erythematosus 4 | 1,057
esophageal adenocarcinoma 4 | 737
group 4 medulloblastoma 4 | 1,855
nasopharyngeal carcinoma 4 | 1,058
primitive neuroectodermal tumor 4 | 3,035
ulcerative colitis 4 | 1,819
Atopic dermatitis 3 | 952
Cataract 3 | 297
Cognitive delay 3 | 608
Diarrhea 3 | 253
Dull intelligence 3 | 645
Electroretinogram abnormal 3 | 95
Gaucher disease type 1 3 | 180
Global developmental delay 3 | 608
Hypertension 3 | 396
Hypertensive disease 3 | 292
Intellectual disability 3 | 1,016
Lens Opacities 3 | 231
Low intelligence 3 | 645
Lung disease 3 | 142
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Poor school performance 3 | 645
Retinitis Pigmentosa 3 | 226
active Crohn's disease 3 | 922
acute myeloid leukemia 3 | 783
astrocytic glioma 3 | 2,597
diabetes mellitus 3 | 1,728
ductal carcinoma in situ 3 | 1,744
pediatric high grade glioma 3 | 1,064
Abortion, Spontaneous 2 | 109
Acquired metabolic disease 2 | 336
Anteverted nostril 2 | 191
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Difficulties with night vision 2 | 87
Duchenne muscular dystrophy 2 | 601
Hepatomegaly 2 | 285
Inflammatory bowel disease 2 | 151
Kidney disease 2 | 430
Melanoma 2 | 711
Motor delay 2 | 147
Multiple Sclerosis 2 | 540
Night Blindness 2 | 101
No development of motor milestones 2 | 147
Pick disease 2 | 1,894
Spontaneous abortion 2 | 113
Usher syndrome 2 | 32
active ulcerative colitis 2 | 764
adrenocortical carcinoma 2 | 1,428
atypical teratoid/rhabdoid tumor 2 | 357
juvenile dermatomyositis 2 | 1,187
medulloblastoma 2 | 720
non diabetic and post-ischemic heart failure 2 | 200
pancreatic carcinoma 2 | 562
posterior fossa group A ependymoma 2 | 468
primary pancreatic ductal adenocarcinoma 2 | 1,108
spina bifida 2 | 1,074
tuberculosis 2 | 2,010
type II diabetes mellitus and post-ischemic heart failure 2 | 88

Tissue

Blood and immune system 26 | 16,909
Endocrine System 26 | 18,159
Skin and soft tissues 26 | 17,230
Female tissues 25 | 17,400
Liver and Pancreas 25 | 16,750
Male tissues 25 | 17,142
Urinary Tract 25 | 16,678
Digestive Tract 24 | 17,369
Respiratory system 24 | 16,393
Cardiovascular System 23 | 15,192
Nervous System 23 | 16,725

Target Family

Non-IDG 19 | 12,091
Enzyme 4 | 4,145
Kinase 1 | 634
Transcription Factor 1 | 1,400
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Vasopressin-neurophysin 2-copeptin AVP Tbio Non-IDG -3.92570 8381.2 203
Cytochrome b-245 light chain CYBA Tbio Non-IDG -2.58058 376.0 164
Pre-mRNA-processing factor 6 PRPF6 Tbio Non-IDG -1.39926 24.5 171
Estradiol 17-beta-dehydrogenase 1 HSD17B1 Tchem Enzyme -2.36315 220.8 198
N-chimaerin CHN1 Tbio Non-IDG -2.41669 255.8 297
Serpin B5 SERPINB5 Tbio Non-IDG -3.04576 1104.8 385
Outer dense fiber protein 3-like protein 2 ODF3L2 Tdark Non-IDG 0.60 0.18 24
E3 ubiquitin-protein ligase RNF25 RNF25 Tbio Enzyme -2.54549 332.4 118
Prefoldin subunit 6 PFDN6 Tbio Non-IDG -1.56814 35.1 59
Leptin receptor LEPR Tclin Non-IDG -3.01833 782.6 615