Development Level

Tbio 16 | 10,625
Tchem 1 | 1,890
Tclin 1 | 602
Tdark 1 | 7,003

IMPC Term

impaired righting response 19 | 19
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat/hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

psoriasis 12 | 6,685
glioblastoma 10 | 5,572
ovarian cancer 9 | 8,492
medulloblastoma, large-cell 8 | 6,234
osteosarcoma 8 | 7,933
pilocytic astrocytoma 8 | 3,086
Breast cancer 6 | 3,099
lung cancer 6 | 4,473
lung carcinoma 6 | 2,844
malignant mesothelioma 6 | 3,163
pituitary cancer 6 | 1,972
posterior fossa group A ependymoma 6 | 1,511
subependymal giant cell astrocytoma 6 | 2,287
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
oligodendroglioma 5 | 2,849
pediatric high grade glioma 5 | 2,712
atypical teratoid / rhabdoid tumor 4 | 4,369
colon cancer 4 | 1,475
ependymoma 4 | 2,514
interstitial cystitis 4 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
lung adenocarcinoma 4 | 2,714
primitive neuroectodermal tumor 4 | 3,031
Cancer 3 | 2,346
Retinitis pigmentosa 3 | 156
Rheumatoid Arthritis 3 | 1,171
adult high grade glioma 3 | 2,148
atypical teratoid/rhabdoid tumor 3 | 1,095
cutaneous lupus erythematosus 3 | 1,056
cystic fibrosis 3 | 1,670
esophageal adenocarcinoma 3 | 737
invasive ductal carcinoma 3 | 2,950
medulloblastoma 3 | 1,524
nasopharyngeal carcinoma 3 | 1,056
non-small cell lung cancer 3 | 2,798
pancreatic cancer 3 | 2,300
sonic hedgehog group medulloblastoma 3 | 1,482
ulcerative colitis 3 | 2,087
Blindness 2 | 84
Carcinoma 2 | 2,147
Cleft palate 2 | 125
Colorectal Neoplasms 2 | 217
Epilepsy 2 | 346
Hypertension 2 | 293
Hypertensive disease 2 | 193
Kidney disease 2 | 397
Liver Cirrhosis 2 | 101
Lung disease 2 | 136
Multiple myeloma 2 | 1,328
Nonsyndromic deafness 2 | 121
Pick disease 2 | 1,893
Sensorineural hearing loss 2 | 107
Spontaneous abortion 2 | 108
Substance Withdrawal Syndrome 2 | 55
Usher Syndrome, Type 1 2 | 7
Usher syndrome 2 | 34
X-linked cerebral adrenoleukodystrophy 2 | 115
astrocytic glioma 2 | 2,241
astrocytoma 2 | 1,493
breast carcinoma 2 | 1,614
diabetes mellitus 2 | 1,663
non primary Sjogren syndrome sicca 2 | 840
primary Sjogren syndrome 2 | 789
type II diabetes mellitus and post-ischemic heart failure 2 | 89
Acne vulgaris 1 | 16
Amnestic disorder 1 | 37
Ascariasis 1 | 7
Cardiac arrhythmia 1 | 26
Cholera 1 | 33
Deafness, Autosomal Recessive 18 1 | 1
Deafness, autosomal recessive, 18A 1 | 1
Diarrhea 1 | 155
Eosinophilic esophagitis 1 | 31
Gastroenteritis 1 | 46
Heart Diseases 1 | 42
Hypokalemia 1 | 40
Hypopituitarism 1 | 36
Hypotension 1 | 53
Ischemia 1 | 27
Kidney Failure, Chronic 1 | 45
Klippel-Feil syndrome 1 | 14
Lung Injury 1 | 20
Meniere's disease 1 | 25
Pain 1 | 70
Periodontal disease 1 | 37
Prevention of Radiation-Induced Nausea and Vomiting 1 | 7
Psychotic Disorders 1 | 20
Pulmonary Fibrosis 1 | 66
Refractive error 1 | 43
Schistosomiasis 1 | 38
Short bowel syndrome 1 | 16
Sick sinus syndrome 1 | 14
Small cell carcinoma of lung 1 | 45
Townes-Brocks syndrome 1 | 15
USHER SYNDROME, TYPE IC 1 | 1
Usher syndrome 1C 1 | 1
Usher syndrome type 1C 1 | 1
Usher syndrome, type 1C 1 | 1
rhinitis with controlled asthma 1 | 8

Tissue

Cardiovascular System 19 | 17,958
Digestive Tract 19 | 18,473
Endocrine System 19 | 18,512
Female tissues 19 | 18,647
Nervous System 19 | 18,561
Urinary Tract 19 | 18,444
Blood and immune system 18 | 17,995
Liver and Pancreas 18 | 18,136
Respiratory system 18 | 17,484
Skin and soft tissues 18 | 18,115
Male tissues 17 | 17,969

Target Family

Non-IDG 13 | 11,969
Enzyme 2 | 4,146
Ion Channel 1 | 341
Kinase 1 | 634
TF/Epigenetic 1 | 38
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Unconventional myosin-VIIa MYO7A Tbio Non-IDG -2.10835 131.7 114
Vasopressin-neurophysin 2-copeptin AVP Tbio Non-IDG -3.91847 8071.2 168
Harmonin USH1C Tbio Non-IDG -2.07484 115.8 173
Estradiol 17-beta-dehydrogenase 1 HSD17B1 Tchem Enzyme -2.33011 205.7 174
Cytochrome b-245 light chain CYBA Tbio Non-IDG -2.56763 358.8 154
Prefoldin subunit 6 PFDN6 Tbio Non-IDG -1.48185 28.0 49
N-chimaerin CHN1 Tbio Non-IDG -2.39897 241.1 189
Pre-mRNA-processing factor 6 PRPF6 Tbio Non-IDG -1.35844 27.6 163
Guanine nucleotide-binding protein G(o) subunit alpha GNAO1 Tbio Non-IDG -2.22825 154.8 177
Hyaluronan and proteoglycan link protein 1 HAPLN1 Tbio Non-IDG -2.16781 139.0 128