Development Level

Tbio 53 | 11,445
Tdark 9 | 6,588
Tchem 7 | 1,598
Tclin 6 | 613

Collection

Ion Channel: IDG Consortium (T... 2 | 99
GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

impaired glucose tolerance 75 | 75
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 59 | 11,493
ovarian cancer 42 | 8,520
osteosarcoma 37 | 7,950
psoriasis 35 | 6,694
glioblastoma 27 | 5,792
medulloblastoma, large-cell 27 | 6,241
lung cancer 24 | 4,740
Kidney cancer 23 | 2,613
Breast cancer 20 | 3,578
atypical teratoid / rhabdoid tumor 20 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
Cancer 17 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
adult high grade glioma 16 | 3,801
ependymoma 16 | 4,679
subependymal giant cell astrocytoma 16 | 2,287
group 3 medulloblastoma 15 | 4,104
lung carcinoma 15 | 2,843
invasive ductal carcinoma 14 | 2,951
lung adenocarcinoma 14 | 2,716
malignant mesothelioma 14 | 3,232
Autosomal recessive predisposition 13 | 1,442
interstitial cystitis 13 | 2,312
Epilepsy 12 | 792
Intellectual disability 12 | 1,016
Pick disease 12 | 1,894
breast carcinoma 12 | 1,638
acute myeloid leukemia 11 | 783
Seizures 10 | 596
diabetes mellitus 10 | 1,728
primitive neuroectodermal tumor 10 | 3,035
ulcerative colitis 10 | 1,819
Astrocytoma, Pilocytic 9 | 3,081
Cognitive delay 9 | 608
Global developmental delay 9 | 608
Mental and motor retardation 9 | 608
Obesity 9 | 678
Schizophrenia 9 | 1,160
astrocytic glioma 9 | 2,597
ductal carcinoma in situ 9 | 1,745
group 4 medulloblastoma 9 | 1,855
non-small cell lung cancer 9 | 2,890
Atopic dermatitis 8 | 952
Small head 8 | 374
oligodendroglioma 8 | 2,850
pediatric high grade glioma 8 | 1,064
Bipolar Disorder 7 | 666
Muscle hypotonia 7 | 571
cutaneous lupus erythematosus 7 | 1,057
pancreatic cancer 7 | 2,398
pituitary cancer 7 | 1,972
posterior fossa group A ependymoma 7 | 468
Dull intelligence 6 | 645
Fetal Growth Retardation 6 | 189
Infant, Small for Gestational Age 6 | 176
Intrauterine retardation 6 | 176
Liver cancer 6 | 604
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Poor school performance 6 | 645
Prostatic Neoplasms 6 | 495
Rheumatoid arthritis 6 | 1,191
colon cancer 6 | 1,478
gastric carcinoma 6 | 807
spina bifida 6 | 1,074
Acquired scoliosis 5 | 281
Curvature of spine 5 | 282
Duchenne muscular dystrophy 5 | 601
Failure to gain weight 5 | 365
Pediatric failure to thrive 5 | 365
adrenocortical carcinoma 5 | 1,428
nasopharyngeal carcinoma 5 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
primary Sjogren syndrome 5 | 735
Attention deficit hyperactivity disorder 4 | 278
Endometrial cancer 4 | 311
Hydrocephalus 4 | 152
Hyperreflexia 4 | 209
Hypertension 4 | 396
Melanoma 4 | 711
Motor delay 4 | 147
Neurodegenerative disease 4 | 414
Neuropathy 4 | 261
No development of motor milestones 4 | 147
Prenatal onset 4 | 139
Short nose 4 | 132
Short stature 4 | 531
Skin cancer 4 | 469
Small nose 4 | 132
Strabismus 4 | 270
Vascular disease 4 | 319
acute quadriplegic myopathy 4 | 1,158
astrocytoma 4 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
cystic fibrosis 4 | 1,696
dermatomyositis 4 | 966
juvenile dermatomyositis 4 | 1,187
non primary Sjogren syndrome sicca 4 | 891

Tissue

Endocrine System 72 | 18,159
Digestive Tract 71 | 17,369
Female tissues 70 | 17,400
Male tissues 70 | 17,142
Liver and Pancreas 69 | 16,750
Nervous System 69 | 16,725
Respiratory system 69 | 16,393
Skin and soft tissues 69 | 17,230
Urinary Tract 67 | 16,678
Blood and immune system 66 | 16,909
Cardiovascular System 66 | 15,192

Target Family

Non-IDG 37 | 12,091
Enzyme 11 | 4,145
Transcription Factor 6 | 1,400
Ion Channel 5 | 344
Epigenetic 4 | 242
Transporter 4 | 473
GPCR 3 | 408
Kinase 3 | 634
TF/Epigenetic 2 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
Sodium/potassium-transporting ATPase subunit alpha-4 ATP1A4 Tclin Transporter -1.73566 51.3 5
Aquaporin-1 AQP1 Tbio Non-IDG -3.08125 1107.4 374
Bromodomain adjacent to zinc finger domain protein 2A BAZ2A Tchem TF/Epigenetic -2.07564 115.2 51
Calcium and integrin-binding protein 1 CIB1 Tbio Non-IDG -2.08897 121.1 264
Follistatin-related protein 1 FSTL1 Tbio Non-IDG -1.98038 117.5 265
Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 Tbio Ion Channel -1.46356 25.4 471
CTD small phosphatase-like protein CTDSPL Tbio Enzyme -2.17507 152.7 141
Serine/threonine-protein kinase N3 PKN3 Tbio Kinase -1.19026 15.5 133
Histone-lysine N-methyltransferase NSD3 NSD3 Tbio Epigenetic -1.36629 23.0 234