Development Level

Tbio 67 | 10,625
Tchem 9 | 1,890
Tdark 9 | 7,003
Tclin 4 | 602

IMPC Term

hypoactivity 89 | 89
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat/hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

ovarian cancer 55 | 8,484
psoriasis 45 | 6,685
osteosarcoma 43 | 7,933
medulloblastoma, large-cell 41 | 6,234
glioblastoma 37 | 5,572
atypical teratoid / rhabdoid tumor 35 | 4,369
lung cancer 27 | 4,466
Breast cancer 25 | 3,094
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,289
oligodendroglioma 25 | 2,849
pilocytic astrocytoma 23 | 3,086
primitive neuroectodermal tumor 23 | 3,031
ependymoma 20 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,988
pediatric high grade glioma 19 | 2,712
invasive ductal carcinoma 18 | 2,950
lung carcinoma 18 | 2,844
Pick disease 17 | 1,893
adult high grade glioma 17 | 2,148
pancreatic cancer 17 | 2,300
subependymal giant cell astrocytoma 17 | 2,287
astrocytic glioma 16 | 2,241
interstitial cystitis 15 | 2,299
group 3 medulloblastoma 14 | 2,254
lung adenocarcinoma 14 | 2,713
malignant mesothelioma 14 | 3,162
medulloblastoma 14 | 1,524
non-small cell lung cancer 14 | 2,798
breast carcinoma 13 | 1,614
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,795
Cancer 12 | 2,346
Carcinoma 12 | 2,147
cystic fibrosis 12 | 1,665
ductal carcinoma in situ 12 | 1,745
pituitary cancer 12 | 1,972
sonic hedgehog group medulloblastoma 12 | 1,482
adrenocortical carcinoma 10 | 1,427
astrocytoma 10 | 1,493
diabetes mellitus 10 | 1,663
juvenile dermatomyositis 10 | 1,189
tuberculosis 10 | 1,557
ulcerative colitis 10 | 2,087
cutaneous lupus erythematosus 9 | 1,056
group 4 medulloblastoma 9 | 1,875
posterior fossa group A ependymoma 9 | 1,511
posterior fossa group B ependymoma 9 | 1,530
primary pancreatic ductal adenocarcinoma 9 | 1,271
Multiple myeloma 8 | 1,327
Rheumatoid Arthritis 8 | 1,160
gastric carcinoma 8 | 832
Obesity 7 | 616
colon cancer 7 | 1,475
Down syndrome 6 | 548
Waldenstrons macroglobulinemia 6 | 765
acute quadriplegic myopathy 6 | 1,157
dermatomyositis 6 | 933
Atopic dermatitis 5 | 944
Autistic Disorder 5 | 320
Intellectual disability 5 | 573
Schizophrenia 5 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 499
fibroadenoma 5 | 557
primary Sjogren syndrome 5 | 789
spina bifida 5 | 1,064
urothelial carcinoma 5 | 318
Acquired metabolic disease 4 | 267
Alzheimer's disease 4 | 644
IGA Glomerulonephritis 4 | 454
Liver Cirrhosis 4 | 101
Neurodegenerative disease 4 | 383
Retinitis pigmentosa 4 | 153
active ulcerative colitis 4 | 477
acute myeloid leukemia 4 | 780
aldosterone-producing adenoma 4 | 664
atypical teratoid/rhabdoid tumor 4 | 1,095
chronic rhinosinusitis 4 | 512
nephrosclerosis 4 | 329
progressive supranuclear palsy 4 | 674
tuberculosis and treatment for 6 months 4 | 686
Adenoid Cystic Carcinoma 3 | 99
Dementia 3 | 129
Hypertension 3 | 287
Hypertensive disease 3 | 193
Infertility 3 | 163
Kidney disease 3 | 396
Neuropathy 3 | 210
Parkinson's disease 3 | 364
Peripheral Neuropathy 3 | 303
Stomach Neoplasms 3 | 282
nasopharyngeal carcinoma 3 | 1,056
non-small cell lung carcinoma 3 | 413
pancreatic carcinoma 3 | 567
sarcoidosis 3 | 358
Atrial Fibrillation 2 | 110
Brain Ischemia 2 | 87
Diabetes Mellitus, Non-Insulin-Dependent 2 | 157
Mucopolysaccharidosis 2 | 24
Multiple Sclerosis 2 | 498
Vascular disease 2 | 281

Tissue

Blood and immune system 89 | 17,995
Digestive Tract 89 | 18,473
Endocrine System 89 | 18,512
Female tissues 89 | 18,647
Nervous System 89 | 18,561
Cardiovascular System 88 | 17,958
Liver and Pancreas 88 | 18,136
Male tissues 88 | 17,969
Skin and soft tissues 88 | 18,115
Urinary Tract 88 | 18,444
Respiratory system 86 | 17,484

Target Family

Non-IDG 43 | 11,971
Enzyme 29 | 4,146
Transcription Factor 7 | 1,400
Epigenetic 3 | 242
GPCR 2 | 406
TF/Epigenetic 2 | 38
Transporter 2 | 473
Kinase 1 | 634

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CD5 antigen-like CD5L Tbio Non-IDG -1.78447 64.4 287
Cytochrome b561 CYB561 Tbio Non-IDG -1.41910 20.4 45
Inactive ribonuclease-like protein 10 RNASE10 Tdark Enzyme -0.65321 4.33 16
Glycine amidinotransferase, mitochondrial GATM Tbio Enzyme -2.31313 210.4 193
ELMO domain-containing protein 2 ELMOD2 Tbio Non-IDG -0.39155 3.05 81
Leptin receptor LEPR Tclin Non-IDG -2.98449 751.7 530
Forkhead box protein P2 FOXP2 Tbio Transcription Factor -2.45964 292.2 303
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial CYP27B1 Tchem Enzyme -2.65191 464.3 66
Ubiquitin-conjugating enzyme E2 D3 UBE2D3 Tbio Non-IDG -1.23367 18.0 133
Mammalian ependymin-related protein 1 EPDR1 Tbio Non-IDG -1.11130 15.5 108