Development Level

Tbio 93 | 11,445
Tdark 31 | 6,588
Tclin 13 | 613
Tchem 11 | 1,598

Collection

GPCR: IDG Consortium (Targets) 3 | 126
GPCR: IDG Consortium (Complete... 1 | 25
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

hyperactivity 148 | 148
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 97 | 11,493
medulloblastoma, large-cell 76 | 6,241
ovarian cancer 72 | 8,520
glioblastoma 69 | 5,792
osteosarcoma 65 | 7,950
atypical teratoid / rhabdoid tumor 62 | 5,112
ependymoma 58 | 4,679
psoriasis 57 | 6,694
adult high grade glioma 54 | 3,801
group 3 medulloblastoma 51 | 4,104
Astrocytoma, Pilocytic 44 | 3,081
oligodendroglioma 43 | 2,850
primitive neuroectodermal tumor 39 | 3,035
astrocytic glioma 38 | 2,597
lung cancer 38 | 4,740
malignant mesothelioma 35 | 3,232
Breast cancer 33 | 3,578
lung carcinoma 32 | 2,843
subependymal giant cell astrocytoma 30 | 2,287
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 27 | 2,955
Pick disease 26 | 1,894
pituitary cancer 26 | 1,972
invasive ductal carcinoma 24 | 2,951
non-small cell lung cancer 24 | 2,890
Kidney cancer 23 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
lung adenocarcinoma 23 | 2,716
Cancer 22 | 2,499
pancreatic cancer 22 | 2,398
cystic fibrosis 17 | 1,696
Schizophrenia 16 | 1,160
group 4 medulloblastoma 16 | 1,855
interstitial cystitis 16 | 2,312
tuberculosis 16 | 2,010
Autosomal recessive predisposition 15 | 1,442
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
Epilepsy 14 | 792
spina bifida 14 | 1,074
Intellectual disability 13 | 1,016
adrenocortical carcinoma 13 | 1,428
acute myeloid leukemia 12 | 783
colon cancer 12 | 1,478
ductal carcinoma in situ 12 | 1,745
primary pancreatic ductal adenocarcinoma 12 | 1,109
Muscle hypotonia 11 | 571
Rheumatoid arthritis 11 | 1,191
breast carcinoma 11 | 1,638
diabetes mellitus 11 | 1,728
fibroadenoma 11 | 559
pediatric high grade glioma 11 | 1,064
progressive supranuclear palsy 11 | 676
Cognitive delay 10 | 608
Dull intelligence 10 | 645
Global developmental delay 10 | 608
Low intelligence 10 | 645
Mental Retardation 10 | 645
Mental and motor retardation 10 | 608
Mental deficiency 10 | 645
Nystagmus 10 | 317
Poor school performance 10 | 645
active ulcerative colitis 10 | 764
astrocytoma 10 | 1,146
medulloblastoma 10 | 720
Bipolar Disorder 9 | 666
Parkinson's disease 9 | 392
aldosterone-producing adenoma 9 | 665
juvenile dermatomyositis 9 | 1,187
Attention deficit hyperactivity disorder 8 | 278
Depressive disorder 8 | 409
Endometriosis 8 | 540
esophageal adenocarcinoma 8 | 737
non primary Sjogren syndrome sicca 8 | 891
ulcerative colitis 8 | 1,819
Alcoholic Intoxication, Chronic 7 | 289
Mental Depression 7 | 333
Multiple Sclerosis 7 | 540
Neurodegenerative disease 7 | 414
Optic Atrophy 7 | 242
Prostatic Neoplasms 7 | 495
chronic rhinosinusitis 7 | 512
cutaneous lupus erythematosus 7 | 1,057
Broad flat nasal bridge 6 | 236
Cerebral atrophy 6 | 178
Nasal bridge wide 6 | 236
Obesity 6 | 678
Seizures 6 | 596
active Crohn's disease 6 | 922
dermatomyositis 6 | 966
nasopharyngeal carcinoma 6 | 1,058
tuberculosis and treatment for 6 months 6 | 409
Atopic dermatitis 5 | 952
Down syndrome 5 | 499
Duchenne muscular dystrophy 5 | 601
Hypertension 5 | 396
Melanoma 5 | 711
Multiple myeloma 5 | 1,332
acute quadriplegic myopathy 5 | 1,158
atypical teratoid/rhabdoid tumor 5 | 357
gastric carcinoma 5 | 807

Tissue

Endocrine System 146 | 18,159
Digestive Tract 143 | 17,369
Female tissues 143 | 17,400
Skin and soft tissues 143 | 17,230
Liver and Pancreas 142 | 16,750
Nervous System 142 | 16,725
Blood and immune system 141 | 16,909
Male tissues 140 | 17,142
Respiratory system 134 | 16,393
Urinary Tract 133 | 16,678
Cardiovascular System 132 | 15,192

Target Family

Non-IDG 84 | 12,091
Enzyme 31 | 4,145
GPCR 8 | 408
Ion Channel 8 | 344
Transcription Factor 5 | 1,400
Kinase 4 | 634
Epigenetic 3 | 242
Transporter 3 | 473
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
F-box only protein 11 FBXO11 Tbio Non-IDG -1.53905 34.1 258
Beta-citrylglutamate synthase B RIMKLB Tdark Enzyme -0.33579 2.63 48
Transmembrane protein 14A TMEM14A Tbio Non-IDG -0.33645 3.05 17
Pre-mRNA-splicing factor RBM22 RBM22 Tbio Non-IDG -0.84549 7.65 130
Mitochondrial import inner membrane translocase subunit Tim22 TIMM22 Tbio Enzyme -0.80456 5.81 19
Potassium voltage-gated channel subfamily D member 3 KCND3 Tclin Ion Channel -2.34610 217.9 162
Choline transporter-like protein 1 SLC44A1 Tbio Transporter -1.60796 43.9 212
Bcl-2-binding component 3 BBC3 Tbio Non-IDG -2.02081 88.0 559
Probable G-protein coupled receptor 22 GPR22 Tdark GPCR -0.60233 4.92 193