Development Level

Tbio 41 | 11,445
Tdark 7 | 6,588
Tchem 4 | 1,598
Tclin 1 | 613

Collection

Ion Channel: IDG Consortium (T... 2 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

hydrometra 53 | 53
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 26 | 11,493
ovarian cancer 24 | 8,520
osteosarcoma 22 | 7,950
psoriasis 19 | 6,694
atypical teratoid / rhabdoid tumor 15 | 5,112
medulloblastoma, large-cell 13 | 6,241
interstitial cystitis 12 | 2,312
lung cancer 12 | 4,740
Autosomal recessive predisposition 11 | 1,442
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
glioblastoma 10 | 5,792
invasive ductal carcinoma 10 | 2,951
lung carcinoma 10 | 2,843
group 3 medulloblastoma 9 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
lung adenocarcinoma 9 | 2,716
non-small cell lung cancer 9 | 2,890
Breast cancer 8 | 3,578
group 4 medulloblastoma 8 | 1,855
malignant mesothelioma 8 | 3,232
Astrocytoma, Pilocytic 7 | 3,081
Cancer 7 | 2,499
Kidney cancer 7 | 2,613
adult high grade glioma 7 | 3,801
Schizophrenia 6 | 1,160
cutaneous lupus erythematosus 6 | 1,057
ependymoma 6 | 4,679
oligodendroglioma 6 | 2,850
Muscle hypotonia 5 | 571
breast carcinoma 5 | 1,638
cystic fibrosis 5 | 1,696
diabetes mellitus 5 | 1,728
ductal carcinoma in situ 5 | 1,745
pancreatic cancer 5 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pituitary cancer 5 | 1,972
subependymal giant cell astrocytoma 5 | 2,287
ulcerative colitis 5 | 1,819
Carcinoma, Hepatocellular 4 | 228
Dull intelligence 4 | 645
Intellectual disability 4 | 1,016
Liver carcinoma 4 | 240
Low intelligence 4 | 645
Melanoma 4 | 711
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Nystagmus 4 | 317
Pick disease 4 | 1,894
Poor school performance 4 | 645
adrenocortical carcinoma 4 | 1,428
astrocytic glioma 4 | 2,597
colon cancer 4 | 1,478
posterior fossa group A ependymoma 4 | 468
primary Sjogren syndrome 4 | 735
primitive neuroectodermal tumor 4 | 3,035
Arthralgia 3 | 90
Arthritis 3 | 290
Asthma 3 | 385
Cognitive delay 3 | 608
Conductive hearing loss 3 | 123
Edema 3 | 81
Global developmental delay 3 | 608
Hepatomegaly 3 | 285
Hypertensive disease 3 | 292
Kidney Diseases 3 | 114
Kidney damage 3 | 25
Low set ears 3 | 181
Low-set, posteriorly rotated ears 3 | 110
Mental and motor retardation 3 | 608
Myalgia 3 | 54
Pancreatitis 3 | 123
Posteriorly rotated ear 3 | 61
Prostatic Neoplasms 3 | 495
Rheumatoid arthritis 3 | 1,191
Short neck 3 | 140
Short stature 3 | 531
Splenomegaly 3 | 190
active Crohn's disease 3 | 922
acute quadriplegic myopathy 3 | 1,158
cystic fibrosis and chronic rhinosinusitis 3 | 214
esophageal adenocarcinoma 3 | 737
fibroadenoma 3 | 559
juvenile dermatomyositis 3 | 1,187
nasopharyngeal carcinoma 3 | 1,058
sonic hedgehog group medulloblastoma 3 | 467
spina bifida 3 | 1,074
Alzheimer's disease 2 | 658
Arthritis, Juvenile 2 | 126
Atherosclerosis 2 | 291
Atopic dermatitis 2 | 952
Broad flat nasal bridge 2 | 236
Decreased joint mobility 2 | 53
Delayed bone age 2 | 136
Failure to gain weight 2 | 365
Hypersensitivity reaction type II disease 2 | 253
Hypertension 2 | 396
Nasal bridge wide 2 | 236
Pediatric failure to thrive 2 | 365
tuberculosis 2 | 2,010

Tissue

Endocrine System 51 | 18,159
Female tissues 51 | 17,400
Male tissues 51 | 17,142
Skin and soft tissues 51 | 17,230
Blood and immune system 50 | 16,909
Digestive Tract 50 | 17,369
Liver and Pancreas 49 | 16,750
Urinary Tract 49 | 16,678
Respiratory system 48 | 16,393
Nervous System 46 | 16,725
Cardiovascular System 41 | 15,192

Target Family

Non-IDG 28 | 12,091
Enzyme 15 | 4,145
Ion Channel 3 | 344
Epigenetic 2 | 242
Kinase 2 | 634
Transcription Factor 2 | 1,400
GPCR 1 | 408

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pannexin-2 PANX2 Tbio Ion Channel -1.77864 56.1 126
Transmembrane protein 160 TMEM160 Tdark Non-IDG 0.38 0.37 10
Growth/differentiation factor 2 GDF2 Tbio Non-IDG -2.16825 176.4 239
Poly(ADP-ribose) glycohydrolase PARG Tchem Enzyme -2.32776 229.4 126
ETS domain-containing transcription factor ERF ERF Tbio Transcription Factor -2.42588 268.8 257
Neuroguidin NGDN Tbio Non-IDG -2.22456 133.1 93
Poly(A) RNA polymerase, mitochondrial MTPAP Tbio Enzyme -1.36829 24.0 68
Platelet glycoprotein Ib beta chain GP1BB Tbio Non-IDG -1.79873 57.4 87
Protein ABHD11 ABHD11 Tbio Enzyme -0.85496 5.74 96
Stromal cell-derived factor 1 CXCL12 Tbio Non-IDG -3.48446 3085.9 607