Development Level

Tbio 9 | 11,445
Tdark 3 | 6,588
Tchem 1 | 1,598
Tclin 1 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

hydroencephaly 14 | 14
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

osteosarcoma 8 | 7,950
Carcinoma 7 | 11,493
ovarian cancer 5 | 8,520
glioblastoma 4 | 5,792
non-small cell lung cancer 4 | 2,890
Astrocytoma, Pilocytic 3 | 3,081
ependymoma 3 | 4,679
group 3 medulloblastoma 3 | 4,104
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
lung cancer 3 | 4,740
medulloblastoma, large-cell 3 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Melanoma 2 | 711
Obesity 2 | 678
Split hand-foot malformation 2 | 18
acute quadriplegic myopathy 2 | 1,158
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
group 4 medulloblastoma 2 | 1,855
lung adenocarcinoma 2 | 2,716
pancreatic cancer 2 | 2,398
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
psoriasis 2 | 6,694
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Absent finger 1 | 4
Acquired metabolic disease 1 | 336
Amyotrophic lateral sclerosis 1 | 451
Arthritis 1 | 290
Atherosclerosis 1 | 291
Autistic Disorder 1 | 364
Breast Neoplasms 1 | 445
Carcinoma, squamous cell of head and neck 1 | 31
Claw hand 1 | 26
Colitis 1 | 54
Colorectal Neoplasms 1 | 243
Congenital stationary night blindness 1 | 29
Congenital stationary night blindness 1B 1 | 6
Cornelia de Lange syndrome 1 | 21
Decreased projection of maxilla 1 | 66
Decreased size of teeth 1 | 62
Decreased width of tooth 1 | 59
Deficiency of upper jaw bones 1 | 66
Dermatitis, Allergic Contact 1 | 67
EEC syndrome 1 | 8
Eaton-Lambert syndrome 1 | 40
Fatty liver disease 1 | 103
Gestational trophoblastic neoplasm 1 | 17
Hyperandrogenism 1 | 34
Hypertension 1 | 396
Hypodontia 1 | 81
Hypoplasia of the maxilla 1 | 66
Hypotrophic maxilla 1 | 66
Inflammatory Bowel Diseases 1 | 35
Inflammatory bowel disease 2 1 | 8
Inflammatory bowel disease 5 1 | 14
Latent syphilis 1 | 3
Mammary Neoplasms 1 | 425
Maxillary retrognathia 1 | 66
Microdontia (disorder) 1 | 59
Miller-Dieker lissencephaly syndrome 1 | 19
Missing more than six teeth 1 | 22
Mouth Neoplasms 1 | 55
Multiple Sclerosis 1 | 540
Neoplasm Recurrence, Local 1 | 37
Night Blindness 1 | 101
Night blindness, congenital stationary 1 | 16
Oligodontia 1 | 24
Osteoporosis 1 | 363
Pick disease 1 | 1,894
Polycystic ovary syndrome 1 | 360
Retrusion of upper jaw bones 1 | 66
Syndactyly of fingers 1 | 48
Syndactyly of the toes 1 | 45
Syndactyly, Mesoaxial Synostotic, with Phalangeal Reduction 1 | 1
Tooth agenesis 1 | 44
Urinary bladder cancer 1 | 36
acute myeloid leukemia 1 | 783
adrenocortical carcinoma 1 | 1,428
astrocytoma 1 | 1,146
axial spondyloarthropathy 1 | 28
breast carcinoma 1 | 1,638
chronic lymphosyte leukemia 1 | 204
chronic rhinosinusitis 1 | 512
cone-rod dystrophy 1 | 59
cystic fibrosis and chronic rhinosinusitis 1 | 214
dermatomyositis 1 | 966
head and neck cancer 1 | 271
hepatocellular carcinoma 1 | 547
interstitial lung disease 1 | 298
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
nasopharyngeal carcinoma 1 | 1,058
permanent atrial fibrillation 1 | 45
progressive supranuclear palsy 1 | 676
spina bifida 1 | 1,074
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 13 | 16,909
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Urinary Tract 13 | 16,678
Digestive Tract 12 | 17,369
Nervous System 12 | 16,725
Skin and soft tissues 12 | 17,230
Respiratory system 11 | 16,393
Cardiovascular System 10 | 15,192

Target Family

Non-IDG 9 | 12,091
Enzyme 3 | 4,145
Ion Channel 1 | 344
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Putative ADP-ribosylation factor-like protein 5C ARL5C Tdark Enzyme 0.00000 1.00 39
Rho guanine nucleotide exchange factor 15 ARHGEF15 Tbio Non-IDG -0.90240 8.54 26
Palmitoyltransferase ZDHHC3 ZDHHC3 Tbio Enzyme -1.42827 26.4 87
Class A basic helix-loop-helix protein 9 BHLHA9 Tbio Transcription Factor -1.06508 12.1 64
Phosphatidylinositol glycan anchor biosynthesis class U protein PIGU Tbio Non-IDG -0.98044 9.33 20
Disks large homolog 5 DLG5 Tbio Non-IDG -1.71553 56.2 60
Calcium-binding protein 4 CABP4 Tbio Non-IDG -1.57906 38.7 144
Nicotinamide phosphoribosyltransferase NAMPT Tchem Enzyme -2.94790 1054.3 667
Epidermal growth factor-like protein 8 EGFL8 Tdark Non-IDG -1.65003 39.7 50
Transmembrane emp24 domain-containing protein 10 TMED10 Tbio Non-IDG -1.46644 31.9 300